Molecular model of naphthalene-induced DNA damage in the murine lung

Autor: Simon G. Royce, Mimi L.K. Tang, Michelle M. Tang, Assam El-Osta, Tom C. Karagiannis, Christian Orlowski, Xuelei Li

Publikováno v: Humanexperimental toxicology. 31(1)

Airway epithelial damage and repair represents a novel therapeutic target in asthma and chronic obstructive pulmonary disease. An established mouse model of airway epithelial damage involves the Clara cell cytotoxicity of parenterally administered na

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a75ed16818edc33a298149b03ad5da17
https://pubmed.ncbi.nlm.nih.gov/21508073

Trichostatin A accentuates doxorubicin-induced hypertrophy in cardiac myocytes

Autor: Jun Okabe, Lisa Chang, Michelle M. Tang, Ann J E Lin, Katherine Ververis, Tom C. Karagiannis, Assam El-Osta

Publikováno v: Aging (Albany NY)

Histone deacetylase inhibitors represent a new class of anticancer therapeutics and the expectation is that they will be most effective when used in combination with conventional cancer therapies, such as the anthracycline, doxorubicin. The dose-limi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3d37e1ebc188e90f456e75511395be
https://pubmed.ncbi.nlm.nih.gov/20930262

Quantitation of γH2AX Foci in Tissue Samples

Autor: Simon G. Royce, George T. Georgiadis, Li-Jeen Mah, Michelle M. Tang, Assam El-Osta, Raja S. Vasireddy, Tom C. Karagiannis

DNA double-strand breaks (DSBs) are particularly lethal and genotoxic lesions, that can arise either by endogenous (physiological or pathological) processes or by exogenous factors, particularly ionizing radiation and radiomimetic compounds. Phosphor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::138fcc8f717b0418c8a0517e77ef4358
https://europepmc.org/articles/PMC3156060/

Amiodarone-Induced Anaphylaxis.

Autor: Tang M; Department of Biomedical Sciences, Rocky Vista University College of Osteopathic Medicine, Ivins, UT, USA., Nunna N; Department of Biomedical Sciences, Rocky Vista University College of Osteopathic Medicine, Ivins, UT, USA., Zhong Q; Department of Biomedical Sciences, Rocky Vista University College of Osteopathic Medicine, Ivins, UT, USA.

Publikováno v: Journal of pharmacy practice [J Pharm Pract] 2024 Aug 13, pp. 8971900241273241. Date of Electronic Publication: 2024 Aug 13.

Large-scale validation of skin prion seeding activity as a biomarker for diagnosis of prion diseases.

Autor: Zhang W; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.; Department of Neurology, The First Hospital of Jilin University, Changchun, 130021, Jilin Province, China., Orrú CD; Laboratory of Persistent Viral Diseases, NIH/NIAID Rocky Mountain Laboratories, 903 S 4 St., Hamilton, MT, 59840, USA., Foutz A; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA., Ding M; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.; Department of Neurology, The First Hospital of Jilin University, Changchun, 130021, Jilin Province, China., Yuan J; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA., Shah SZA; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA., Zhang J; Department of Population and Quantitative Health Science, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA., Kotobelli K; National Prion Disease Pathology Surveillance Center, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA., Gerasimenko M; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA., Gilliland T; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA., Chen W; National Prion Disease Pathology Surveillance Center, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA., Tang M; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA., Cohen M; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA., Safar J; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA., Xu B; Department of Pharmaceutical Sciences, North Carolina Central University, Durham, NC, 27707, USA., Hong DJ; Institute of Neurology and Department of Neurology, Jiangxi Academy of Clinical Medical Sciences, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, Jiangxi Province, China., Cui L; Department of Neurology, The First Hospital of Jilin University, Changchun, 130021, Jilin Province, China., Hughson AG; Laboratory of Persistent Viral Diseases, NIH/NIAID Rocky Mountain Laboratories, 903 S 4 St., Hamilton, MT, 59840, USA., Schonberger LB; Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA, 30329, USA., Tatsuoka C; Department of Medicine, University of Pittsburgh, Pittsburgh, PA, 15232, USA., Chen SG; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, 35233, USA., Greenlee JJ; Virus and Prion Research Unit, National Animal Disease Center, USDA, Agricultural Research Service, 1920 Dayton Avenue, Ames, IA, 50010, USA., Wang Z; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA., Appleby BS; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.; National Prion Disease Pathology Surveillance Center, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.; Department of Neurology, University Hospitals Cleveland Medical Center and Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA., Caughey B; Laboratory of Persistent Viral Diseases, NIH/NIAID Rocky Mountain Laboratories, 903 S 4 St., Hamilton, MT, 59840, USA. bcaughey@niaid.nih.gov., Zou WQ; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA. wenquanzou@ncu.edu.cn.; National Prion Disease Pathology Surveillance Center, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA. wenquanzou@ncu.edu.cn.; Institute of Neurology and Department of Neurology, Jiangxi Academy of Clinical Medical Sciences, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, Jiangxi Province, China. wenquanzou@ncu.edu.cn.; Department of Neurology, University Hospitals Cleveland Medical Center and Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA. wenquanzou@ncu.edu.cn.

Publikováno v: Acta neuropathologica [Acta Neuropathol] 2024 Jan 17; Vol. 147 (1), pp. 17. Date of Electronic Publication: 2024 Jan 17.