Zobrazeno 1 - 10 of 18 pro vyhledávání: '"Michelle M. Shimogawa"'
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Akademický článek
FAP106 is an interaction hub for assembling microtubule inner proteins at the cilium inner junction
Autor: Michelle M. Shimogawa, Angeline S. Wijono, Hui Wang, Jiayan Zhang, Jihui Sha, Natasha Szombathy, Sabeeca Vadakkan, Paula Pelayo, Keya Jonnalagadda, James Wohlschlegel, Z. Hong Zhou, Kent L. Hill
Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Motility of pathogenic protozoa depends on flagella (synonymous with cilia) with axonemes containing nine doublet microtubules (DMTs) and two singlet microtubules. Microtubule inner proteins (MIPs) within DMTs influence axoneme stability and
Externí odkaz: https://doaj.org/article/743b9fffbf724d74a32dfd2a0cc1187a
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3
FAP106 is an interaction hub required for assembly of conserved and lineage-specific microtubule inner proteins at the cilium inner junction
Autor: Michelle M. Shimogawa, Angeline S. Wijono, Hui Wang, Jiayan Zhang, Jihui Sha, Natasha Szombathy, Sabeeca Vadakkan, Paula Pelayo, Keya Jonnalagadda, James Wohlschlegel, Z. Hong Zhou, Kent L. Hill
Motility of pathogenic protozoa depends on flagella (synonymous with cilia) with axonemes containing nine doublet microtubules (DMTs) and two singlet microtubules. Microtubule inner proteins (MIPs) within DMTs influence axoneme stability and motility
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::706ce78396af52dc3bdc9a91235879a5
https://doi.org/10.1101/2022.11.11.516029
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5
Abstract P407: Role Of Cyclic AMP During The Intracellular Infection Cycle Of Trypanosoma Cruzi
Autor: Kent L. Hill, Daniel E. Vélez-Ramírez, Michelle M. Shimogawa
Publikováno v: Circulation Research. 129
Trypanosoma cruzi is the causative agent of Chagas disease, a vector-borne disease. In the 1990s the distribution of the vector, a hematophagous triatomine, and consequently the parasite, was from the southeast tropical regions of Mexico to South Ame
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c3e7e8ee51339ff6fc9bf8d7b1915ab0
https://doi.org/10.1161/res.129.suppl_1.p407
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6
APEX2 proximity proteomics resolves flagellum subdomains and identifies flagellum tip-specific proteins in Trypanosoma brucei
Autor: Kent L. Hill, Shima Rayatpisheh, Michelle M. Shimogawa, Sunayan S. Ray, Samuel Dean, James A. Wohlschlegel, Marcus Gallagher-Jones, Andrew Lopez, Daniel E. Vélez-Ramírez, Gerasimos Langousis
Publikováno v: mSphere
mSphere, vol 6, iss 1
mSphere, Vol 6, Iss 1 (2021)
Sleeping sickness is a neglected tropical disease caused by the protozoan parasite Trypanosoma brucei. The disease disrupts the sleep-wake cycle, leading to coma and death if left untreated. T. brucei motility, transmission, and virulence depend on i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58cec03547055cdea391852f1b666166
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7
Motility-based label-free detection of parasites in bodily fluids using holographic speckle analysis and deep learning
Autor: Yi Luo, Michelle M. Shimogawa, Kent L. Hill, Aydogan Ozcan, Tairan Liu, Hongda Wang, Sener Yalcin, Yibo Zhang, Hatice Ceylan Koydemir, Yujia Huang, Vittorio Bianco, Bijie Bai, Ilker Oguz, Rohan Nadkarni, Bohan Zhang, Alexander Guziak, Yilin Luo, Zhensong Wei
Publikováno v: Light: Science & Applications, Vol 7, Iss 1, Pp 1-18 (2018)
Light, science & applications, vol 7, iss 1
Light, Science & Applications
Parasitic infections constitute a major global public health issue. Existing screening methods that are based on manual microscopic examination often struggle to provide sufficient volumetric throughput and sensitivity to facilitate early diagnosis.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c187be17694a274818d0faba0c2d080f
http://link.springer.com/article/10.1038/s41377-018-0110-1
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9
Parasite motility is critical for virulence of African trypanosomes
Autor: Aydogan Ozcan, Michelle M. Shimogawa, Sunayan S. Ray, Yibo Zhang, Kent L. Hill, Quanjie Geng, Neville K. Kisalu
Publikováno v: Scientific reports, vol 8, iss 1
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
African trypanosomes, Trypanosoma brucei spp., are lethal pathogens that cause substantial human suffering and limit economic development in some of the world’s most impoverished regions. The name Trypanosoma (“auger cell”) derives from the par
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446a677547e67469ec147a77b37e1d3e
https://escholarship.org/uc/item/70d1760h
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10
Loss of the BBSome perturbs endocytic trafficking and disrupts virulence of Trypanosoma brucei
Autor: Kent L. Hill, Michelle M. Shimogawa, Gerasimos Langousis, Maxence V. Nachury, Edwin A. Saada, Andrew R. Nager, James A. Wohlschlegel, William D. Barshop, Ajay A. Vashisht, Roberto Spreafico
Publikováno v: Langousis, G; Shimogawa, MM; Saada, EA; Vashisht, AA; Spreafico, R; Nager, AR; et al.(2016). Loss of the BBSome perturbs endocytic trafficking and disrupts virulence of Trypanosoma brucei. Proceedings of the National Academy of Sciences of the United States of America, 113(3), 632-637. doi: 10.1073/pnas.1518079113. UCLA: Retrieved from: http://www.escholarship.org/uc/item/4gd4611j
© 2016, National Academy of Sciences. All rights reserved. Cilia (eukaryotic flagella) are present in diverse eukaryotic lineages and have essential motility and sensory functions. The cilium's capacity to sense and transduce extracellular signals d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::223abd0e6c1a72c1d5e8058af7e8a703
https://doi.org/10.1073/pnas.1518079113
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