Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Michelle M. Lian"'
Autor:
Yi Jayne Tan, Alisa C. W. Yong, Jia Nee Foo, Michelle M. Lian, Weng Khong Lim, Jacqueline Dominguez, Zhi Hui Fong, Kaavya Narasimhalu, Hui Jin Chiew, Kok Pin Ng, Simon K. S. Ting, Nagaendran Kandiah, Adeline S. L. Ng
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 4, Pp 568-578 (2023)
Abstract Objective Frontotemporal dementia (FTD) encompasses a spectrum of neurodegenerative disorders, including behavioural variant FTD (bvFTD), semantic variant primary progressive aphasia (svPPA) and non‐fluent variant PPA (nfvPPA). While a str
Externí odkaz:
https://doaj.org/article/7f489c93b3ec4a15afdbc836d867afa0
Autor:
Jacqueline Dominguez, Jeryl Tan Yu, Yi Jayne Tan, Arlene Ng, Ma Fe De Guzman, Boots Natividad, Ma Luisa Daroy, Jemellee Cano, Justine Yu, Michelle M. Lian, Li Zeng, Weng Khong Lim, Jia Nee Foo, Adeline S. L. Ng
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Frontotemporal Dementia (FTD) is a common cause of Young Onset Dementia and has diverse clinical manifestations involving behavior, executive function, language and motor function, including parkinsonism. Up to 50% of FTD patients report a positive f
Externí odkaz:
https://doaj.org/article/4afb50e68e1c44d0ae5e01ca165644ac
Autor:
Zhiyong Chen, Yi Jayne Tan, Michelle M. Lian, Moses Tandiono, Jia Nee Foo, Weng Khong Lim, Nagaendran Kandiah, Eng-King Tan, Adeline S. L. Ng
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Leukodystrophies are a diverse group of genetic disorders that selectively involve the white matter of the brain and are a frequent cause of young-onset cognitive impairment. Genetic diagnosis is challenging. Data on the utility of incorporating brai
Externí odkaz:
https://doaj.org/article/b9a4a51bf4ec409c9ba639daf29f93d2
Autor:
Jia Nee Foo, David L. Silver, Minni Chua, Markus Rennie Wenk, Chew Egy, Zheng X, Federico Torta, Ho Qwc, Yusuf Ali, Michelle M. Lian, Per Olof Berggren, Sneha Muralidharan, Olga Stelmashenko
Western type diets are linked to obesity and diabetes partly because of their high saturated fatty acid (SFA) content. We found that SFAs, but not unsaturated fatty acids (USFAs), reduced the number of lipid droplets (LDs) within pancreatic β-cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03142a02c6f9bc08971b84483b36966a
https://doi.org/10.1101/2021.02.28.433270
https://doi.org/10.1101/2021.02.28.433270
Autor:
Wutian Wu, Vincent Po Hen Lin, Sing Yian Chew, Michelle M. Lian, Jia Nee Foo, Na Zhang, Ulla Milbreta, Jiah Shin Chin, Junquan Lin, Kunyu Zhang, Elaine Guo Yan Chew
Publikováno v:
Advanced Science
Advanced Science, Vol 8, Iss 15, Pp n/a-n/a (2021)
Advanced Science, Vol 8, Iss 15, Pp n/a-n/a (2021)
Current treatment approaches toward spinal cord injuries (SCI) have mainly focused on overcoming the inhibitory microenvironment that surrounds lesion sites. Unfortunately, the mere modulation of the cell/tissue microenvironment is often insufficient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc226dba1687ae1107109d7d32fc1e7a
https://hdl.handle.net/10356/150957
https://hdl.handle.net/10356/150957
Autor:
Qingfeng Chen, Josep M. Campistol, Pin Li, Jia Nee Foo, Bingrui Zhou, Tian Zhang, Mingliang Fang, Elaine Guo Yan Chew, Jian Hui Low, Yun Xia, Kylie Su Mei Yong, Meng Liu, Emi Aizawa, Chiea Chuen Khor, Concepcion Rodriguez Esteban, Michelle M. Lian, Keiichiro Suzuki, Juan Carlos Izpisua Belmonte
Publikováno v:
Cell Stem Cell
Summary Human pluripotent stem cell-derived kidney organoids recapitulate developmental processes and tissue architecture, but intrinsic limitations, such as lack of vasculature and functionality, have greatly hampered their application. Here we esta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f821560395e2b81ccb73fe36d96f5b
https://europepmc.org/articles/PMC6731150/
https://europepmc.org/articles/PMC6731150/
Autor:
Manuel Irimia, Byrappa Venkatesh, Sydney Brenner, Masanori Kasahara, Jeremy B. Swann, Yoichi Sutoh, Yuko Ohta, Wesley C. Warren, Brian J. Raney, Shawn Hoon, Richard K. Wilson, Vydianathan Ravi, Shufen Ho, Patrick Minx, LaDeana W. Hillier, Sumanty Tohari, Vamshidhar Gangu, Belen Lorente-Galdos, Alice Tay, Michelle M. Lian, Ashish K. Maurya, Scott William Roy, Igor Kondrychyn, Philip W. Ingham, Alison P. Lee, Zhi Wei Lim, Martin F. Flajnik, Vladimir Korzh, Kiat Whye Kong, Javier Quilez, Thomas Boehm, Boon-Hui Tay, Tomas Marques-Bonet
Publikováno v:
Nature
The emergence of jawed vertebrates (gnathostomes) from jawless vertebrates was accompanied by major morphological and physiological innovations, such as hinged jaws, paired fins and immunoglobulin-based adaptive immunity. Gnathostomes subsequently di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1171b3e00ac1979fef5bb1e87df93d9c
https://doi.org/10.1038/s41586-020-2967-4
https://doi.org/10.1038/s41586-020-2967-4
Autor:
Yin Xia Chao, Louis C.S. Tan, Rong Peng, Yongping Chen, Ai Huey Tan, Kyuyoung Song, Jing Yang, Anne Y.Y. Chan, Yuming Xu, Yaping Yan, Changhe Shi, Jianjun Liu, Juei-Jueng Lin, Lulu Jiang, Mike A. Nalls, Wing Lok Au, Shen-Yang Lim, Michelle M. Lian, Zhong Pei, Huifang Shang, Wataru Satake, Eng-King Tan, Azlina Ahmad Annuar, Wee-Yang Meah, Vincent Mok, Chun-Feng Liu, Cheng-Jie Mao, Kumar M. Prakash, Baorong Zhang, Jia Nee Foo, Ling Chen, Yih-Ru Wu, Jia Lun Lim, Chiea Chuen Khor, Beom S. Jeon, Woon-Puay Koh, Cornelis Blauwendraat, Kin Y. Mok, Tatsushi Toda, Renshi Xu, Ebonne Yulin Ng, Elaine Guo Yan Chew, Shi Qi Mok, Sun Ju Chung, Moses Tandiono
Publikováno v:
JAMA Neurology. 77:746
Importance Large-scale genome-wide association studies in the European population have identified 90 risk variants associated with Parkinson disease (PD); however, there are limited studies in the largest population worldwide (ie, Asian). Objectives
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2450b40df715ae53eca4fb2fc2d157fa
https://doi.org/10.1001/jamaneurol.2020.0428
https://doi.org/10.1001/jamaneurol.2020.0428
Autor:
Huanming Yang, Boon-Hui Tay, Hao Yu, Michelle M. Lian, Guojie Zhang, Hailin Pan, Vydianathan Ravi, Byrappa Venkatesh, Cai Li, Alison P. Lee, Sydney Brenner, Jian Wang
Publikováno v:
Pan, H, Yu, H, Ravi, V, Li, C, Lee, A P, Lian, M M, Tay, B-H, Brenner, S, Wang, J, Yang, H, Zhang, G & Venkatesh, B 2016, ' The genome of the largest bony fish, ocean sunfish ( Mola mola ), provides insights into its fast growth rate ', GigaScience, vol. 5, 36 . https://doi.org/10.1186/s13742-016-0144-3
GigaScience
GigaScience
Background The ocean sunfish (Mola mola), which can grow up to a length of 2.7 m and weigh 2.3 tons, is the world’s largest bony fish. It has an extremely fast growth rate and its endoskeleton is mainly composed of cartilage. Another unique feature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54c7912b19006adf15b498b247624463
https://doi.org/10.1186/s13742-016-0144-3
https://doi.org/10.1186/s13742-016-0144-3
Autor:
Nisha E. Pillai, Wei-Ping Yu, Michelle M. Lian, Boon-Hui Tay, Sumanty Tohari, Byrappa Venkatesh, Sydney Brenner, Vydianathan Ravi
Publikováno v:
Molecular biology and evolution. 33(2)
The brain, comprising billions of neurons and intricate neural networks, is arguably the most complex organ in vertebrates. The diversity of individual neurons is fundamental to the neuronal network complexity and the overall function of the vertebra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b10622266e0f77f8fe77b81f41581fd
https://pubmed.ncbi.nlm.nih.gov/26545918
https://pubmed.ncbi.nlm.nih.gov/26545918