Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Michelle M. Kameda-Smith"'
Autor:
Michelle M. Kameda-Smith, Helen Zhu, En-Ching Luo, Yujin Suk, Agata Xella, Brian Yee, Chirayu Chokshi, Sansi Xing, Frederick Tan, Raymond G. Fox, Ashley A. Adile, David Bakhshinyan, Kevin Brown, William D. Gwynne, Minomi Subapanditha, Petar Miletic, Daniel Picard, Ian Burns, Jason Moffat, Kamil Paruch, Adam Fleming, Kristin Hope, John P. Provias, Marc Remke, Yu Lu, Tannishtha Reya, Chitra Venugopal, Jüri Reimand, Robert J. Wechsler-Reya, Gene W. Yeo, Sheila K. Singh
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
MYC amplification is an independent prognostic factor for the most aggressive subgroup (Group 3) of pediatric medulloblastoma (G3 MB). Here, the authors highlight the role of the RNA-binding protein, Musashi-1 (MSI1) in G3 MB and identify MSI1-bound
Externí odkaz:
https://doaj.org/article/3eace71e4f774decb598d79c690ed3aa
Autor:
Branavan Manoranjan, Chitra Venugopal, David Bakhshinyan, Ashley A. Adile, Laura Richards, Michelle M. Kameda-Smith, Owen Whitley, Anna Dvorkin-Gheva, Minomi Subapanditha, Neil Savage, Nazanin Tatari, Dillon McKenna, Blessing Bassey-Archibong, Neil Winegarden, Robin Hallett, John P. Provias, Blake Yarascavitch, Olufemi Ajani, Adam Fleming, Gary D. Bader, Trevor J. Pugh, Bradley W. Doble, Sheila K. Singh
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The Wnt molecular subgroup of medulloblastoma is associated with better prognosis than the other molecular subgroups. Here, the authors show that activating Wnt signaling impairs tumor development and improves survival in Group 3 and Group 4 medullob
Externí odkaz:
https://doaj.org/article/90b86d3d0f9c41078f2e0a70337929d5
Autor:
Ashley A. Adile, Michelle M. Kameda-Smith, David Bakhshinyan, Laura Banfield, Sabra K. Salim, Forough Farrokhyar, Adam J. Fleming
Publikováno v:
Systematic Reviews, Vol 9, Iss 1, Pp 1-9 (2020)
Abstract Background Central nervous system tumors remain the leading cause of cancer-related mortality amongst children with solid tumors, with medulloblastoma (MB) representing the most common pediatric brain malignancy. Despite best current therapi
Externí odkaz:
https://doaj.org/article/34293094f61d4862ae0face0faf10346
Autor:
Michelle M. Kameda-Smith, Helen Zhu, En-Ching Luo, Yujin Suk, Agata Xella, Brian Yee, Chirayu Chokshi, Sansi Xing, Frederick Tan, Raymond G. Fox, Ashley A. Adile, David Bakhshinyan, Kevin Brown, William D. Gwynne, Minomi Subapanditha, Petar Miletic, Daniel Picard, Ian Burns, Jason Moffat, Kamil Paruch, Adam Fleming, Kristin Hope, John P. Provias, Marc Remke, Yu Lu, Tannishtha Reya, Chitra Venugopal, Jüri Reimand, Robert J. Wechsler-Reya, Gene W. Yeo, Sheila K. Singh
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/a3f8e3d5b4894e4aa4350454d71f0f4e
Autor:
Sara Badodi, Adrian Dubuc, Xinyu Zhang, Gabriel Rosser, Mariane Da Cunha Jaeger, Michelle M. Kameda-Smith, Anca Sorana Morrissy, Paul Guilhamon, Philipp Suetterlin, Xiao-Nan Li, Loredana Guglielmi, Ashirwad Merve, Hamza Farooq, Mathieu Lupien, Sheila K. Singh, M. Albert Basson, Michael D. Taylor, Silvia Marino
Publikováno v:
Cell Reports, Vol 21, Iss 10, Pp 2772-2784 (2017)
Summary: We describe molecular convergence between BMI1 and CHD7 in the initiation of medulloblastoma. Identified in a functional genomic screen in mouse models, a BMI1High;CHD7Low expression signature within medulloblastoma characterizes patients wi
Externí odkaz:
https://doaj.org/article/60f4f3d022f54adf9316a3789fd48058
Autor:
Michelle M. Kameda-Smith, Malavan Ragulojan, Shannon Hart, Taylor R. Duda, Mark A. MacLean, Jonathan Chainey, Minoo Aminnejad, Michael Rizzuto, David Bergeron, Mathew Eagles, Alan Chalil, Anne-Mare Langlois, Charles Gariepy, Amit Persad, Mohammed Hasen, Alick Wang, Lior Elkaim, Sean Christie, Forough Farrokhyar, Kesava Reddy
Publikováno v:
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques. :1-8
Objective: Intracerebral abscess is a life-threatening condition for which there are no current, widely accepted neurosurgical management guidelines. The purpose of this study was to investigate Canadian practice patterns for the medical and surgical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb393096f0e41f9d11633efb3ae5708
https://doi.org/10.1017/cjn.2022.299
https://doi.org/10.1017/cjn.2022.299
Publikováno v:
Critical Reviews in Biomedical Engineering. 49:13-70
Acute ischemic stroke (AIS) is a significant cause of global morbidity and mortality, with functional implications for quality of life and long-term disability. The limitations of intravenous thrombolytic therapy for the treatment of AIS, especially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac15a2cef28dc89ad19c2cc0ee562c46
https://doi.org/10.1615/critrevbiomedeng.2022042563
https://doi.org/10.1615/critrevbiomedeng.2022042563
Autor:
Michelle M. Kameda-Smith, Taylor Duda, Donald B. Duncan, Malavan Ragulojan, Yongkyung Jung, Forough Farrokhyar, Cheryl Main, Kesava Reddy
Publikováno v:
World neurosurgery. 165
This study analyzed patient, radiologic, and clinical factors associated with operative brain abscesses and patients' functional outcomes.A retrospective analysis was conducted of neurosurgical cases of brain abscesses from 2009 to 2019 at a Canadian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c056650c8222c7f65f93613449be8183
https://pubmed.ncbi.nlm.nih.gov/35798293
https://pubmed.ncbi.nlm.nih.gov/35798293
Autor:
Matthew E. Eagles, Mark A. MacLean, Michelle M. Kameda-Smith, Taylor Duda, Amit R. L. Persad, Alysa Almojuela, Rakan Bokhari, Christian Iorio-Morin, Lior M. Elkaim, Michael A. Rizzuto, Stephen P. Lownie, Sean D. Christie, Jeanne Teitelbaum
Publikováno v:
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques.
Introduction:Delayed cerebral ischemia (DCI) is a complication of aneurysmal subarachnoid hemorrhage (aSAH) and is associated with significant morbidity and mortality. There is little high-quality evidence available to guide the management of DCI. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a611ad4a87f980a0ac46aed504143447
https://pubmed.ncbi.nlm.nih.gov/35477442
https://pubmed.ncbi.nlm.nih.gov/35477442
Autor:
David Bakhshinyan, Ashley A. Adile, Jeff Liu, William D. Gwynne, Yujin Suk, Stefan Custers, Ian Burns, Mohini Singh, Nicole McFarlane, Minomi K. Subapanditha, Maleeha A. Qazi, Parvez Vora, Michelle M. Kameda-Smith, Neil Savage, Kim L. Desmond, Nazanin Tatari, Damian Tran, Mathieu Seyfrid, Kristin Hope, Nicholas A. Bock, Chitra Venugopal, Gary D. Bader, Sheila K. Singh
Publikováno v:
Science Advances
Description
Gene expression profiling of medulloblastoma cells undergoing therapy identifies BPIFB4 as a novel target for recurrent disease.
Medulloblastoma (MB) remains a leading cause of cancer-related mortality among children. The paucit
Gene expression profiling of medulloblastoma cells undergoing therapy identifies BPIFB4 as a novel target for recurrent disease.
Medulloblastoma (MB) remains a leading cause of cancer-related mortality among children. The paucit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff934887f48ef8f639df88ddc2b49cd
http://europepmc.org/articles/PMC8654291
http://europepmc.org/articles/PMC8654291