Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Michelle M. Clark"'
Autor:
David Dimmock, Julie A. Cakici, Sara A. Caylor, Michelle M. Clark, Cinnamon S. Bloss, Christina Clarke, Mary Gaughran, Cynthia Triplett, Stephen F. Kingsmore
Publikováno v:
Am J Hum Genet
Rapid diagnostic genomic sequencing recently became feasible for infants in intensive care units (ICUs). However, research regarding parents’ perceived utility, adequacy of consent, and potential harms and benefits is lacking. Herein we report resu
Autor:
Lauge Farnaes, Kelly Watkins, David Dimmock, Jeffrey J. Gold, James C. Perry, Matthew N. Bainbridge, Nicole G. Coufal, Benjamin Briggs, Ami Doshi, Matthew R. Williams, Michele Feddock, Michelle M. Clark, Shareef Nahas, Elizabeth Ingulli, Stephen F. Kingsmore, Erica Sanford, Nathaly M. Sweeney, Shimul Chowdhury
Publikováno v:
Pediatric Critical Care Medicine. 20:1007-1020
Objectives:Genetic disorders are a leading contributor to mortality in the neonatal ICU and PICU in the United States. Although individually rare, there are over 6,200 single-gene diseases, which may preclude a genetic diagnosis prior to ICU admissio
Autor:
Narayanan Veeraraghavan, Michelle M. Clark, John J. Nigro, Charlotte A. Hobbs, Sara A. Caylor, David Dimmock, Nathaly M. Sweeney, Shareef Nahas, Yan Ding, Julie A. Cakici, Sergey Batalov, Stephen F. Kingsmore, Shimul Chowdhury
Publikováno v:
NPJ Genomic Medicine
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-1 (2021)
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-1 (2021)
Congenital heart disease (CHD) is the most common congenital anomaly and a major cause of infant morbidity and mortality. While morbidity and mortality are highest in infants with underlying genetic conditions, molecular diagnoses are ascertained in
Autor:
David Dimmock, Cinnamon S. Bloss, Yan Ding, Kiely N. James, Katarzyna A. Ellsworth, Narayanan Veeraraghavan, Matthew N. Bainbridge, Amy S. Kimball, Jaime Barea, Christina Clarke, Jerica Lenberg, Shareef Nahas, Shimul Chowdhury, Erica Sanford, Patrick Mulrooney, Nathaly M. Sweeney, Sergey Batalov, Lauge Farnaes, Jennie Le, Cynthia Cheung, Mary Gaughran, Leila Schwanemann, Daniken Orendain, Maria Ortiz-Arechiga, Charlotte A. Hobbs, Marva Evans, Kelly Watkins, Marilyn C. Jones, Joshua J.A. Braun, Meredith S. Wright, Terence C. Wong, Carlos Diaz, Mari Tokita, Miguel Del Campo, Brian Lane, Stephen F. Kingsmore, Christian Hansen, Lisa Salz, Michelle M. Clark, Nicole G. Coufal, Casey Cohenmeyer, Joe Gleeson, Seema Rego, Kristen Wigby, Jennifer Friedman, Zaira Bezares, Mark Speziale, Sara A. Caylor, Lance Prince, Richard S. Song, Jose Honold, Albert Oriol, Catherine Yamada, Annette Feigenbaum, Lucitia Van Der Kraan, Sandra Leibel, Denise Suttner, Dana Mashburn, Laurel Moyer, Julie A. Cakici, Lynne M. Bird, Charles Sauer, Daeheon Oh, Iris Reyes, Gail Knight, Michele Feddock, Jeanne Carroll
Publikováno v:
Am J Hum Genet
The second Newborn Sequencing in Genomic Medicine and Public Health (NSIGHT2) study was a randomized, controlled trial of rapid whole-genome sequencing (rWGS) or rapid whole-exome sequencing (rWES) in infants with diseases of unknown etiology in inte
Publikováno v:
The journal of allergy and clinical immunology. In practice. 9(1)
Measurement of genetic diseases as a cause of mortality in infants receiving whole genome sequencing
Autor:
David Dimmock, Audrey Henderson, Christian Hansen, Christina D. Chambers, Charlotte A. Hobbs, Stephen F. Kingsmore, Laura Jeliffe-Pawlowski, Mallory J Owen, Michelle M. Clark
Publikováno v:
npj Genomic Medicine, Vol 5, Iss 1, Pp 1-10 (2020)
NPJ Genomic Medicine
NPJ genomic medicine, vol 5, iss 1
NPJ Genomic Medicine
NPJ genomic medicine, vol 5, iss 1
Understanding causes of infant mortality shapes public health policy and prioritizes diseases for investments in surveillance, intervention and medical research. Rapid genomic sequencing has created a novel opportunity to decrease infant mortality as
Autor:
David Dimmock, Dorjee Tamang, Sarah White, Peter Schols, Michelle M. Clark, Zaira Bezares, Richard S. Song, Sandra Leibel, Denise Suttner, Jennie Le, Charlotte A. Hobbs, Casey Cohenmeyer, Katarzyna A. Ellsworth, Brian Lane, Amber Hildreth, Lauge Farnaes, Kelly Watkins, Kiely N. James, Terence C. Wong, Cinnamon S. Bloss, Nicole G. Coufal, Laura Puckett, Mari Tokita, Lance Prince, Amy S. Kimball, Narayanan Veeraraghavan, Shareef Nahas, Cyrielle Kint, Yan Ding, Paulina Ordonez, Jaime Barea, Erica Sanford, Kristen Wigby, Daniken Orendain, Maria Ortiz-Arechiga, Meredith S. Wright, Dana Mashburn, Sara A. Caylor, Nathaly M. Sweeney, Joshua J.A. Braun, Christina Clarke, Audra Wise, Lisa Salz, Charles Sauer, Jenni Friedman, George Chiang, Jerica Lenberg, Mark Speziale, Laurel Moyer, Michele Feddock, Jeanne Carroll, Patrick Mulrooney, Raymond Hovey, Stephen F. Kingsmore, Marva Evans, Sergey Batalov, Albert Oriol, Joe Gleeson, Jose Honold, Carlos Diaz, Mary Gaughran, Julie A. Cakici, Crystal Le, Catherine Yamada, Shimul Chowdhury, Gail Knight, Matthew N. Bainbridge, Lucitia Van Der Kraan, Daeheon Oh, Iris Reyes
Publikováno v:
American journal of human genetics, vol 105, iss 4
The second Newborn Sequencing in Genomic Medicine and Public Health study was a randomized, controlled trial of the effectiveness of rapid whole-genome or -exome sequencing (rWGS or rWES, respectively) in seriously ill infants with diseases of unknow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93db546ed65a145dd456f452b1b6a911
https://escholarship.org/uc/item/9h05k7vh
https://escholarship.org/uc/item/9h05k7vh
Autor:
Michael J. Yaszemski, Sun H. Peck, Michelle M. Clark, Andre J. van Wijnen, Yang Lin, Abdel Moneim Mohamed Ali, Wei Wang, Scott M. Riester, Lachlan J. Smith, William E. Krauss, Matthew P. Abdel, Ahmad Nassr, Lin Cong, Paul M. Huddleston, Bradford L. Currier, Wenchun Qu, Mohamad Bydon, Annalise N. Larson, Mark E. Morrey
Publikováno v:
Journal of Orthopaedic Research®. 36:1356-1369
Degenerative disk disease of the spine is a major cause of back pain and disability. Optimization of regenerative medical therapies for degenerative disk disease requires a deep mechanistic understanding of the factors controlling the structural inte
Autor:
Sara A. Caylor, Shareef Nahas, David Dimmock, John J. Nigro, Shimul Chowdhury, Stephen F. Kingsmore, Michelle M. Clark, Narayanan Veeraraghavan, Julie A. Cakici, Yan Ding, Nathaly M. Sweeney, Sergey Batalov, Charlotte A. Hobbs
Publikováno v:
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-1 (2021)
NPJ Genomic Medicine
NPJ Genomic Medicine
Autor:
Håkon K. Gjessing, Michelle M. Clark, Ashley Moffett, Olympe Chazara, Per Magnus, Eric M. Sobel, Janet S. Sinsheimer
Publikováno v:
Human Heredity. 81:181-193
Background/Aims: Maternal and offspring cell contact at the site of placentation presents a plausible setting for maternal-fetal genotype (MFG) interactions affecting fetal growth. We test hypotheses regarding killer cell immunoglobulin-like receptor