Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Michelle M. Becker"'
Autor:
Nianshuang Wang, Osnat Rosen, Lingshu Wang, Hannah L. Turner, Laura J. Stevens, Kizzmekia S. Corbett, Charles A. Bowman, Jesper Pallesen, Wei Shi, Yi Zhang, Kwanyee Leung, Robert N. Kirchdoerfer, Michelle M. Becker, Mark R. Denison, James D. Chappell, Andrew B. Ward, Barney S. Graham, Jason S. McLellan
Publikováno v:
Cell Reports, Vol 28, Iss 13, Pp 3395-3405.e6 (2019)
Summary: Middle East respiratory syndrome coronavirus (MERS-CoV) emerged into the human population in 2012 and has caused substantial morbidity and mortality. Potently neutralizing antibodies targeting the receptor-binding domain (RBD) on MERS-CoV sp
Externí odkaz:
https://doaj.org/article/9e6ee1ff44574d099fc62bbef6bec225
Autor:
Megan Culler Freeman, Christopher T. Peek, Michelle M. Becker, Everett Clinton Smith, Mark R. Denison
Publikováno v:
mBio, Vol 5, Iss 4 (2014)
ABSTRACT Macropinocytosis is exploited by many pathogens for entry into cells. Coronaviruses (CoVs) such as severe acute respiratory syndrome (SARS) CoV and Middle East respiratory syndrome CoV are important human pathogens; however, macropinocytosis
Externí odkaz:
https://doaj.org/article/ed2ee7acc73d4ae1857ac8007863e319
Autor:
Sudhakar Agnihothram, Boyd L. Yount, Eric F. Donaldson, Jeremy Huynh, Vineet D. Menachery, Lisa E. Gralinski, Rachel L. Graham, Michelle M. Becker, Sakshi Tomar, Trevor D. Scobey, Heather L. Osswald, Alan Whitmore, Robin Gopal, Arun K. Ghosh, Andrew Mesecar, Maria Zambon, Mark Heise, Mark R. Denison, Ralph S. Baric
Publikováno v:
mBio, Vol 5, Iss 2 (2014)
ABSTRACT Cross-species transmission of zoonotic coronaviruses (CoVs) can result in pandemic disease outbreaks. Middle East respiratory syndrome CoV (MERS-CoV), identified in 2012, has caused 182 cases to date, with ~43% mortality, and no small animal
Externí odkaz:
https://doaj.org/article/e9cfa1a0b1b145eba9f257143e0e07a0
Autor:
James D. Chappell, Barney S. Graham, Kizzmekia S. Corbett, Jason S. McLellan, Yi Zhang, Andrew B. Ward, Jesper Pallesen, Mark R. Denison, Kwanyee Leung, Nianshuang Wang, Charles A. Bowman, Osnat Rosen, Laura J. Stevens, Wei Shi, Robert N. Kirchdoerfer, Michelle M. Becker, Hannah L. Turner, Lingshu Wang
Publikováno v:
Cell Reports, Vol 28, Iss 13, Pp 3395-3405.e6 (2019)
Cell Reports
Cell Reports
Summary: Middle East respiratory syndrome coronavirus (MERS-CoV) emerged into the human population in 2012 and has caused substantial morbidity and mortality. Potently neutralizing antibodies targeting the receptor-binding domain (RBD) on MERS-CoV sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e974aac78c280fba7e8ed75f59dc8316
http://www.sciencedirect.com/science/article/pii/S2211124719311003
http://www.sciencedirect.com/science/article/pii/S2211124719311003
Publikováno v:
Environmental Research. 161:364-369
Background In 1997 the U.S. Environmental Protection Agency set the first annual National Ambient Air Quality Standard (NAAQS) for fine particulate matter (PM2.5). Although the weight of scientific evidence has determined that a causal relationship e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::771d50496a0737aaa3bbec5aa56e9511
https://doi.org/10.1016/j.envres.2017.11.025
https://doi.org/10.1016/j.envres.2017.11.025
Autor:
Wei Shi, Robert N. Kirchdoerfer, Erica L. Andres, Barney S. Graham, Mark R. Denison, James D. Chappell, Michelle M. Becker, Arminja N. Kettenbach, Jesper Pallesen, Jason S. McLellan, Andrew B. Ward, Lingshu Wang, Wing-Pui Kong, Kizzmekia S. Corbett, Hannah L. Turner, Christopher A. Cottrell, Daniel Wrapp, Nianshuang Wang
Publikováno v:
Proceedings of the National Academy of Sciences
Middle East respiratory syndrome coronavirus (MERS-CoV) is a lineage C betacoronavirus that since its emergence in 2012 has caused outbreaks in human populations with case-fatality rates of ∼36%. As in other coronaviruses, the spike (S) glycoprotei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bfc90f2f360e461036d377470949f9f
Autor:
Wei Shi, Kathleen M. Tatti, Neeltje van Doremalen, Vincent J. Munster, Jason S. McLellan, M. Gordon Joyce, Lia M. Haynes, Misook Choe, Kayvon Modjarrad, Kevin O. Saunders, Kizzmekia S. Corbett, Robert S. Fischer, Tongqing Zhou, Masaru Kanekiyo, Peter D. Kwong, Nianshuang Wang, James D. Chappell, John R. Mascola, Yi Zhang, Mark R. Denison, Lingshu Wang, Michelle M. Becker, Barney S. Graham, Joseph Van Galen, Rosemarie D. Mason, Wing-Pui Kong
Publikováno v:
Journal of virology. 92(10)
Middle East respiratory syndrome coronavirus (MERS-CoV) causes a highly lethal pulmonary infection with ∼35% mortality. The potential for a future pandemic originating from animal reservoirs or health care-associated events is a major public health
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c374e1cf2756c9a8e827978841440f
https://pubmed.ncbi.nlm.nih.gov/29514901
https://pubmed.ncbi.nlm.nih.gov/29514901
Autor:
Meagan Bolles, Michelle M. Becker, Lance D. Eckerle, Mark R. Denison, Ralph S. Baric, Rachel L. Graham
Publikováno v:
Nature medicine
Nature Medicine
Nature Medicine
Live-attenuated RNA virus vaccines are efficacious but subject to reversion to virulence. Among RNA viruses, replication fidelity is recognized as a key determinant of virulence and escape from antiviral therapy; increased fidelity is attenuating for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d1086af981c49a7c368b110d622239c
https://doi.org/10.1038/nm.2972
https://doi.org/10.1038/nm.2972
Publikováno v:
Virus Evolution: Current Research and Future Directions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34ccd760b852be1bdac5e4a82dac28de
https://doi.org/10.21775/9781910190234.12
https://doi.org/10.21775/9781910190234.12
Autor:
Larissa B. Thackray, Mark R. Denison, Brian C. Miller, Herbert W. Virgin, Michelle M. Becker, Zijiang Zhao, Teresa M Lynn, Eric Ward, Noboru Mizushima
Publikováno v:
Autophagy
Macroautophagy (herein autophagy) is a cellular process, requiring ATG5, by which cells deliver double membrane-bound packets containing cytoplasm or cytoplasmic organelles to the lysosome. This process has been reported in some cases to be antiviral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f60ff1e43037a20f15c2d610f94bb954