Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Michelle M. Aarts"'
Autor:
Naghmeh Lesani, Melanie Ratnam, Michelle M. Aarts, Jonathan H. Chan, Elena Sidorova-Darmos, James H. Eubanks
Publikováno v:
International Journal of Developmental Neuroscience. 69:23-31
TRPM7 and TRPM2 are non-specific cation channels of the Transient Receptor Potential channel superfamily. Each channel has gained attention for their potential to mediate oxidative and anoxic cell death (Rama and Garcia, 2016; Naziroglu, 2011a; Abiri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::506ede05ccc5a38a7284a0dfad25814b
https://doi.org/10.1016/j.ijdevneu.2018.05.008
https://doi.org/10.1016/j.ijdevneu.2018.05.008
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 33:1937-1943
Since the most significant ischemic sequelae occur within hours of stroke, it is necessary to understand how neuronal function changes during this time. While histologic and behavioral models show the extent of stroke-related damage, only in vivo rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112d92bb8ce3fcd4c6441966e4419492
https://doi.org/10.1038/jcbfm.2013.153
https://doi.org/10.1038/jcbfm.2013.153
Publikováno v:
Journal of Neurosurgery. 118:1098-1106
Object The postischemic brain has greater susceptibility to epileptogenic activity than physiologically healthy tissue. Epileptiform discharges are thought to exacerbate postischemic brain function. The aim of this study was to develop an in vivo foc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b47b40b26f82cb5698266cefb9ea9d1
https://doi.org/10.3171/2013.1.jns121059
https://doi.org/10.3171/2013.1.jns121059
Autor:
Michelle M. Aarts, Suhail Asrar
Publikováno v:
Channels. 7:6-16
Ischemic stroke is one of the leading causes of disability and death in the world. Elucidation of the underlying mechanisms associated with neuronal death during this detrimental process has been of significant interest in the field of research. One
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc12b2130aa493c1da324057608b3ad
https://doi.org/10.4161/chan.22824
https://doi.org/10.4161/chan.22824
Autor:
Robert A. Cornell, Kirill Kiselyov, Jaime García-Añoveros, Emily R. Liman, Diana M. Bautista, Michelle M. Aarts
Publikováno v:
The Journal of Neuroscience. 28:11778-11784
At the 2008 Annual Meeting of the Society for Neuroscience, a Mini-Symposium entitled “Contributions of TRP Channels to Neurological Disease” included talks from six heads of newly established laboratories, each with a unique research focus, mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fcbc9a0ec5cd3b6437a60c172383937
https://doi.org/10.1523/jneurosci.3929-08.2008
https://doi.org/10.1523/jneurosci.3929-08.2008
Autor:
Dong Chuan Wu, Michelle M. Aarts, Yu Tian Wang, Ted Weita Lai, Lidong Liu, Ann Marie Craig, Yitao Liu, Tak Pan Wong, Amanda Rooyakkers, Michael Tymianski, Jie Lu
Publikováno v:
The Journal of Neuroscience. 27:2846-2857
Well-documented experimental evidence from bothin vitroandin vivomodels of stroke strongly supports the critical involvement of NMDA receptor-mediated excitotoxicity in neuronal damage after stroke. Despite this, the results of clinical trials testin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eed58a4b0035e5a887baec42d775ebfd
https://doi.org/10.1523/jneurosci.0116-07.2007
https://doi.org/10.1523/jneurosci.0116-07.2007
Autor:
Michael Tymianski, Michelle M. Aarts
Publikováno v:
Current Molecular Medicine. 4:137-147
The central role of glutamate receptors in mediating excitotoxic neuronal death in stroke, epilepsy and trauma has been well established. Glutamate is the major excitatory amino acid transmitter within the CNS and it's signaling is mediated by a numb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2873fe7256636ef1216b502bfdb4415
https://doi.org/10.2174/1566524043479202
https://doi.org/10.2174/1566524043479202
Autor:
Zhi-Gang Xiong, Michael Tymianski, John F. MacDonald, Waldy Cerwinski, Wen Li Wei, Koji Iihara, Mark Arundine, Michelle M. Aarts
Publikováno v:
Cell. 115:863-877
Excitotoxicity in brain ischemia triggers neuronal death and neurological disability, and yet these are not prevented by antiexcitotoxic therapy (AET) in humans. Here, we show that in neurons subjected to prolonged oxygen glucose deprivation (OGD), A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb0ce6834772d7a2a0fc15209b8d14fc
https://doi.org/10.1016/s0092-8674(03)01017-1
https://doi.org/10.1016/s0092-8674(03)01017-1
Autor:
Dashen Wang, David Goltzman, Michelle M. Aarts, Michael C. Naski, Li Cheng, Janet E. Henderson, David M. Ornitz
Publikováno v:
Journal of Bone and Mineral Research. 15:155-165
A G380R substitution in the transmembrane-spanning region of FGFR3 (FGFR3Ach) results in constitutive receptor kinase activity and is the most common cause of achondroplastic dwarfism in humans. The epiphyseal growth plates of affected individuals ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea037cf2abe2f54e15f193cc4d22e97
https://doi.org/10.1359/jbmr.2000.15.1.155
https://doi.org/10.1359/jbmr.2000.15.1.155
Publikováno v:
Journal of Bone and Mineral Research. 14:1493-1503
Previous work has identified the parathyroid hormone-related protein (PTHrP) nucleolar targeting signal (NTS) as both necessary and sufficient for localization of PTHrP to the nucleus and nucleolus of a variety of cells where it is believed to partic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc4186fd304d176afa0851064b7737fe
https://doi.org/10.1359/jbmr.1999.14.9.1493
https://doi.org/10.1359/jbmr.1999.14.9.1493