Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Michelle M van Rossum"'
Autor:
Kalijn F. Bol, Gerty Schreibelt, Martine Bloemendal, Wouter W. van Willigen, Simone Hins-de Bree, Anna L. de Goede, Annemiek J. de Boer, Kevin J. H. Bos, Tjitske Duiveman-de Boer, Michel A. M. Olde Nordkamp, Tom G. M. van Oorschot, Carlijn J. Popelier, Jeanne M. Pots, Nicole M. Scharenborg, Mandy W. M. M. van de Rakt, Valeska de Ruiter, Wilmy S. van Meeteren, Michelle M. van Rossum, Sandra J. Croockewit, Bouke J. Koeneman, Jeroen H. A. Creemers, Inge M. N. Wortel, Caroline Angerer, Mareke Brüning, Katja Petry, Andrzej Dzionek, Astrid A. van der Veldt, Dirk J. van Grünhagen, Johanna E. M. Werner, Johannes J. Bonenkamp, John B. A. G. Haanen, Marye J. Boers-Sonderen, Rutger H. T. Koornstra, Martijn F. Boomsma, Erik H. J. Aarntzen, Martin Gotthardt, James Nagarajah, Theo J. M. de Witte, Carl G. Figdor, Johannes H. W. de Wilt, Johannes Textor, Jan Willem B. de Groot, Winald R. Gerritsen, I. Jolanda M. de Vries
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Autologous natural dendritic cells (nDCs) treatment can induce tumor-specific immune responses and clinical responses in cancer patients. In this phase III clinical trial (NCT02993315), 148 patients with resected stage IIIB/C melanoma were r
Externí odkaz:
https://doaj.org/article/245269452ff04a81b46a9a6846fb6516
Autor:
Patrick A M Jansen, Diana Rodijk-Olthuis, Edward J Hollox, Marijke Kamsteeg, Geuranne S Tjabringa, Gys J de Jongh, Ivonne M J J van Vlijmen-Willems, Judith G M Bergboer, Michelle M van Rossum, Elke M G J de Jong, Martin den Heijer, Andrea W M Evers, Mieke Bergers, John A L Armour, Patrick L J M Zeeuwen, Joost Schalkwijk
Publikováno v:
PLoS ONE, Vol 4, Iss 3, p e4725 (2009)
BackgroundPrevious studies have extensively documented antimicrobial and chemotactic activities of beta-defensins. Human beta-defensin-2 (hBD-2) is strongly expressed in lesional psoriatic epidermis, and recently we have shown that high beta-defensin
Externí odkaz:
https://doaj.org/article/b6b1e9ff82104ec2b1aca2b327370234
Autor:
Patrick L J M Zeeuwen, Gys J de Jongh, Diana Rodijk-Olthuis, Marijke Kamsteeg, Renate M Verhoosel, Michelle M van Rossum, Pieter S Hiemstra, Joost Schalkwijk
Publikováno v:
PLoS ONE, Vol 3, Iss 6, p e2301 (2008)
In the past decades, chronic inflammatory diseases such as psoriasis, atopic dermatitis, asthma, Crohn's disease and celiac disease were generally regarded as immune-mediated conditions involving activated T-cells and proinflammatory cytokines produc
Externí odkaz:
https://doaj.org/article/3a890d0f22654e63b80a26295f97a3b9
Autor:
Gosse J. Adema, Cornelis J. A. Punt, Carl G. Figdor, I. Jolanda M. de Vries, Kris Thielemans, Roel Mus, Danita H. Schuurhuis, Tjitske Duiveman-de Boer, Joannes F. M. Jacobs, Willeke A. M. Blokx, Michelle M. van Rossum, Johannes H. W. de Wilt, Alexandra J. Croockewit, W. Joost Lesterhuis, Kalijn Bol, Gerty Schreibelt, Erik H. J. G. Aarntzen
PDF file, 1359K, Vaccine characteristics of first cycle of all patients. (A) Expression of HLA-ABC, HLA-DR/DP, HLA-DQ, CD80, CD86, CD83, and CCR7 was analyzed by flow cytometry. (B) Tumor antigen expression by DCs 2-4 hrs after electroporation with m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9972bd46e8e67d96947535baab7380c
https://doi.org/10.1158/1078-0432.22454445
https://doi.org/10.1158/1078-0432.22454445
Autor:
Carl G. Figdor, Cornelis J.A. Punt, Gosse J. Adema, Sophie Lucas, Otto C. Boerman, Wim J.G. Oyen, Roel Mus, Michelle M. van Rossum, Sandra Croockewit, Annemiek J. de Boer, Mandy W.M.M. van de Rakt, Nicole M. Scharenborg, Joannes F.M. Jacobs, Erik H.J.G. Aarntzen, Annechien J.A. Lambeck, Gerty Schreibelt, I. Jolanda M. de Vries, W. Joost Lesterhuis
PDF file - 41K, Clinical protocol and immunization schedule.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e8f6b0408be93f19ee1f70b11151f57
https://doi.org/10.1158/1078-0432.22442606.v1
https://doi.org/10.1158/1078-0432.22442606.v1
Autor:
Gosse J. Adema, Cornelis J. A. Punt, Carl G. Figdor, I. Jolanda M. de Vries, Kris Thielemans, Roel Mus, Danita H. Schuurhuis, Tjitske Duiveman-de Boer, Joannes F. M. Jacobs, Willeke A. M. Blokx, Michelle M. van Rossum, Johannes H. W. de Wilt, Alexandra J. Croockewit, W. Joost Lesterhuis, Kalijn Bol, Gerty Schreibelt, Erik H. J. G. Aarntzen
PDF file, 96K, Detection of tumor-specific T cells in SKIL cultures does not require challenge with defined epitopes. Tetramer analysis of SKILs cultured from biopsies of DTH reactions to DCs pulsed with tumor peptides (upper plots) or DCs electropor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b4ecc83c583c748182584f602a6fdd
https://doi.org/10.1158/1078-0432.22454442.v1
https://doi.org/10.1158/1078-0432.22454442.v1
Autor:
Gosse J. Adema, Cornelis J. A. Punt, Carl G. Figdor, I. Jolanda M. de Vries, Kris Thielemans, Roel Mus, Danita H. Schuurhuis, Tjitske Duiveman-de Boer, Joannes F. M. Jacobs, Willeke A. M. Blokx, Michelle M. van Rossum, Johannes H. W. de Wilt, Alexandra J. Croockewit, W. Joost Lesterhuis, Kalijn Bol, Gerty Schreibelt, Erik H. J. G. Aarntzen
Purpose: Electroporation of dendritic cells (DC) with mRNA encoding tumor-associated antigens (TAA) has multiple advantages compared to peptide loading. We investigated the immunologic and clinical responses to vaccination with mRNA-electroporated DC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0f20607083d68d6b75c913531bcc4e
https://doi.org/10.1158/1078-0432.c.6522750.v1
https://doi.org/10.1158/1078-0432.c.6522750.v1
Autor:
Carl G. Figdor, Cornelis J.A. Punt, Gosse J. Adema, Sophie Lucas, Otto C. Boerman, Wim J.G. Oyen, Roel Mus, Michelle M. van Rossum, Sandra Croockewit, Annemiek J. de Boer, Mandy W.M.M. van de Rakt, Nicole M. Scharenborg, Joannes F.M. Jacobs, Erik H.J.G. Aarntzen, Annechien J.A. Lambeck, Gerty Schreibelt, I. Jolanda M. de Vries, W. Joost Lesterhuis
PDF file - 55K, Consort flow chart.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a939f8952daaef6474d303f364d8f30e
https://doi.org/10.1158/1078-0432.22442603.v1
https://doi.org/10.1158/1078-0432.22442603.v1
Autor:
Gosse J. Adema, Cornelis J. A. Punt, Carl G. Figdor, I. Jolanda M. de Vries, Kris Thielemans, Roel Mus, Danita H. Schuurhuis, Tjitske Duiveman-de Boer, Joannes F. M. Jacobs, Willeke A. M. Blokx, Michelle M. van Rossum, Johannes H. W. de Wilt, Alexandra J. Croockewit, W. Joost Lesterhuis, Kalijn Bol, Gerty Schreibelt, Erik H. J. G. Aarntzen
PDF file, 149K, CONSORT flow chart.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595a4d8dee7924abc9129d7e8cfd7422
https://doi.org/10.1158/1078-0432.22454448
https://doi.org/10.1158/1078-0432.22454448
Autor:
I. Jolanda M. de Vries, Carl G. Figdor, Cornelis J.A. Punt, Winald R. Gerritsen, Christian U. Blank, Sander Kelderman, Joannes F.M. Jacobs, Rutger H.T. Koornstra, Sandra A.J. Croockewit, Roel D.M. Mus, Marieke E.B. Welzen, Michelle M. van Rossum, Willeke A.M. Blokx, Katja Petry, Gregor Winkels, Jurjen Tel, Tom G.M. van Oorschot, Michel A.M. Olde Nordkamp, Jeanette M. Pots, Annemiek J. de Boer, Nicole M. Scharenborg, Mandy W.M.M. van de Rakt, Tjitske Duiveman-de Boer, Erik H.J.G. Aarntzen, Florian Wimmers, Harm Westdorp, Kalijn F. Bol, Gerty Schreibelt
Supplementary Figure 3. KLH-specific immune responses before and after DC vaccination. (A) KLH-specific T cell proliferation was analyzed before the first vaccination and after each DC vaccination during the first vaccination cycle in peripheral bloo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce748475936725a8bb47b16d85c4c40
https://doi.org/10.1158/1078-0432.22457933.v1
https://doi.org/10.1158/1078-0432.22457933.v1