Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Michelle M Williams"'
Autor:
Michelle M Williams, Jessica Christenson, Sabrina Hafeez, Li-Wei Kuo, Lyndsey Crump, Nicole S Spoelstra, Kathleen I O’Neill, Jill E Slansky, Jennifer K Richer
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/ecfd8e22ec824c0497c291b7846eb28c
Autor:
Toru Hanamura, Jessica L. Christenson, Kathleen I. O’Neill, Emmanuel Rosas, Nicole S. Spoelstra, Michelle M. Williams, Jennifer K. Richer
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-15 (2021)
Abstract Purpose Accumulating evidence has attracted attention to the androgen receptor (AR) as a biomarker and therapeutic target in breast cancer. We hypothesized that AR activity within the tumor has clinical implications and investigated whether
Externí odkaz:
https://doaj.org/article/0371be8231394e019312e132cfe5dbce
Autor:
Allison M Porman, Justin T Roberts, Emily D Duncan, Madeline L Chrupcala, Ariel A Levine, Michelle A Kennedy, Michelle M Williams, Jennifer K Richer, Aaron M Johnson
Publikováno v:
PLoS Biology, Vol 20, Iss 11, p e3001885 (2022)
N6-methyladenosine (m6A) modification of RNA regulates normal and cancer biology, but knowledge of its function on long noncoding RNAs (lncRNAs) remains limited. Here, we reveal that m6A regulates the breast cancer-associated human lncRNA HOTAIR. Map
Externí odkaz:
https://doaj.org/article/64ddea15eef444408f11c50b7522ba53
Autor:
Michelle M. Williams, Jessica L. Christenson, Kathleen I. O’Neill, Sabrina A. Hafeez, Claire L. Ihle, Nicole S. Spoelstra, Jill E. Slansky, Jennifer K. Richer
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-13 (2021)
Abstract Many immune suppressive mechanisms utilized by triple negative breast cancer (TNBC) are regulated by oncogenic epithelial-to-mesenchymal transition (EMT). How TNBC EMT impacts innate immune cells is not fully understood. To determine how TNB
Externí odkaz:
https://doaj.org/article/60e89acc1885465fafd6cd0d4bea2bf5
Publikováno v:
American journal of physiology. Cell physiology. 323(6)
Metastatic cancer is difficult to treat and is responsible for the majority of cancer-related deaths. After cancer cells initiate metastasis and successfully seed a distant site, resident cells in the tissue play a key role in determining how metasta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b4d20cb0e33b922470f2b0737b2c2d9
https://pubmed.ncbi.nlm.nih.gov/36252127
https://pubmed.ncbi.nlm.nih.gov/36252127
Autor:
Michelle M. Williams, Sabrina A. Hafeez, Jessica L. Christenson, Kathleen I. O’Neill, Nia G. Hammond, Jennifer K. Richer
Publikováno v:
Pharmaceuticals, Vol 14, Iss 11, p 1122 (2021)
Approval of checkpoint inhibitors for treatment of metastatic triple negative breast cancer (mTNBC) has opened the door for the use of immunotherapies against this disease. However, not all patients with mTNBC respond to current immunotherapy approac
Externí odkaz:
https://doaj.org/article/e2edb5704120464694919c5e63ee7665
Autor:
Michelle M. Williams, David B. Vaught, Meghan Morrison Joly, Donna J. Hicks, Violeta Sanchez, Philip Owens, Bushra Rahman, David L. Elion, Justin M. Balko, Rebecca S. Cook
Publikováno v:
Breast Cancer Research, Vol 19, Iss 1, Pp 1-14 (2017)
Abstract Background During pregnancy, as the mammary gland prepares for synthesis and delivery of milk to newborns, a luminal mammary epithelial cell (MEC) subpopulation proliferates rapidly in response to systemic hormonal cues that activate STAT5A.
Externí odkaz:
https://doaj.org/article/52b99fc4988f4463a8d1cbe4035ebc1c
Autor:
Meghan Morrison Joly, Michelle M. Williams, Donna J. Hicks, Bayley Jones, Violeta Sanchez, Christian D. Young, Dos D. Sarbassov, William J. Muller, Dana Brantley-Sieders, Rebecca S. Cook
Publikováno v:
Breast Cancer Research, Vol 19, Iss 1, Pp 1-15 (2017)
Abstract Background The importance of the mTOR complex 2 (mTORC2) signaling complex in tumor progression is becoming increasingly recognized. HER2-amplified breast cancers use Rictor/mTORC2 signaling to drive tumor formation, tumor cell survival and
Externí odkaz:
https://doaj.org/article/398ec463dfb44d96a8fde76022898ffd
Autor:
Jennifer K. Richer, Joel R. Eisner, Anthony Elias, Elaina T. Van Patten, Jordan Reese, G. Devon Trahan, Kenneth L. Jones, Nicole S. Spoelstra, Michelle M. Williams, Kathleen I. O'Neill, Jessica L. Christenson
Single-cell RNAseq of AR expressing MDA-MB-453 TNBC cells. scRNAseq was performed on untreated MDA-MB-453 cells cultured in full serum media. Cells were divided in groups based on their expression of AR, ARLow and ARHigh. (A) tSNE plot of AR levels i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bbf37a51d74bc33ff7d21665e1ab4ca
https://doi.org/10.1158/1535-7163.22522315.v1
https://doi.org/10.1158/1535-7163.22522315.v1
Autor:
Jennifer K. Richer, James R. Lambert, Diana M. Cittelly, Aik-Choon Tan, Jimin Shin, Greg D. Degala, Angelo D'Alessandro, Travis Nemkov, Michael A. Gordon, Michelle M. Williams, Kathleen I. O'Neill, Lisa I. Greene, Jessica L. Christenson, Thomas J. Rogers
Comparison of Gene Signatures following miR-200c Restoration in TNBC Cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55e2e34fce6fd246f0255ad336746aaa
https://doi.org/10.1158/1541-7786.22515610.v1
https://doi.org/10.1158/1541-7786.22515610.v1