Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Michelle M Denomme"'
Autor:
Michelle M Denomme, Jason C Parks, Blair R McCallie, Nathan I McCubbin, William B Schoolcraft, Mandy G Katz-Jaffe
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229904 (2020)
The placental epigenome plays a critical role in regulating mammalian growth and development. Alterations to placental methylation, often observed at imprinted genes, can lead to adverse pregnancy complications such as intrauterine growth restriction
Externí odkaz:
https://doaj.org/article/a1477e38a2ec4f6b94cee179f4435a45
Autor:
Michelle M Denomme, Blair R McCallie, Jason C Parks, William B Schoolcraft, Mandy G Katz-Jaffe
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156980 (2016)
Epigenetic mechanisms such as DNA methylation regulate genomic imprinting and account for the distinct non-equivalence of the parental genomes in the embryo. Chromosomal aneuploidy, a major cause of infertility, distorts this highly regulated dispari
Externí odkaz:
https://doaj.org/article/3cbe2b76598a47b99220f53810d8f2ac
Autor:
Michelle M. Denomme, Blair R. McCallie, Mary E. Haywood, Jason C. Parks, William B. Schoolcraft, Mandy G. Katz-Jaffe
Publikováno v:
Human Genomics, Vol 18, Iss 1, Pp 1-14 (2024)
Abstract Background Advanced paternal age (APA) is associated with adverse outcomes to offspring health, including increased risk for neurodevelopmental disorders. The aim of this study was to investigate the methylome and transcriptome of the first
Externí odkaz:
https://doaj.org/article/ab129e965f4a4f02bf55ec054ab6a50f
Autor:
Michelle M Denomme, Carlee R White, Carolina eGillio-Meina, William A MacDonald, Bonnie J Deroo, Gerald M Kidder, Mellissa RW Mann
Publikováno v:
Frontiers in Genetics, Vol 3 (2012)
Growth and maturation of healthy oocytes within follicles requires bidirectional signaling and intercellular gap junctional communication. Aberrant endocrine signaling and loss of gap junctional communication between the oocyte and granulosa cells le
Externí odkaz:
https://doaj.org/article/a2385e95c87a4befbea2dad99566f38e
Autor:
William B. Schoolcraft, Mary E. Haywood, Michelle M. Denomme, Mandy G. Katz-Jaffe, Blair R. McCallie
Publikováno v:
Fertility and Sterility. 116:309-318
Objective To evaluate the epigenetic consequence of a prolonged disease state of infertility in euploid blastocysts. Design Methylome analysis as well as targeted imprinted methylation and expression analysis on individual human euploid blastocysts e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f29901417beb6314a5a19693b2c82c
https://doi.org/10.1016/j.fertnstert.2021.01.040
https://doi.org/10.1016/j.fertnstert.2021.01.040
Autor:
Rachel Makloski, Jason C. Parks, Michelle M Denomme, Darren K. Griffin, Mandy G. Katz-Jaffe, Mary E. Haywood, William B. Schoolcraft, Blair R. McCallie
Publikováno v:
J Assist Reprod Genet
PURPOSE: To investigate the biological networks associated with DOR in young women and the subsequent molecular impact on preimplantation embryos. METHODS: Whole peripheral blood was collected from patients: young women presenting with diminished ova
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa0c28a899ce0c4e09c679391e0bf5c3
https://doi.org/10.1007/s10815-021-02155-8
https://doi.org/10.1007/s10815-021-02155-8
Publikováno v:
Fertility and Sterility. 118:e346
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bd2f26a65323647ad83046775ae4b00
https://doi.org/10.1016/j.fertnstert.2022.09.145
https://doi.org/10.1016/j.fertnstert.2022.09.145
Autor:
William B. Schoolcraft, Jason C. Parks, Mary E. Haywood, Michelle M. Denomme, Mandy G. Katz-Jaffe
Publikováno v:
Aging Cell
Paternal aging and the prevalence of neurodevelopmental disorders in offspring are well documented. Yet, the underlying mechanism and the mode of inheritance have not been conclusively established. Advancing paternal age is a subtle and varying pheno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e567c6730c4f4c968583f9d7c730386
https://doi.org/10.1111/acel.13178
https://doi.org/10.1111/acel.13178
Autor:
Blair R. McCallie, Jason C. Parks, William B. Schoolcraft, Michelle M. Denomme, Nathan McCubbin, Mandy G. Katz-Jaffe
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 3, p e0229904 (2020)
PLoS ONE, Vol 15, Iss 3, p e0229904 (2020)
The placental epigenome plays a critical role in regulating mammalian growth and development. Alterations to placental methylation, often observed at imprinted genes, can lead to adverse pregnancy complications such as intrauterine growth restriction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::301fcfa3de7ef791dd5b30c75ad483b7
http://europepmc.org/articles/PMC7059926
http://europepmc.org/articles/PMC7059926
Publikováno v:
Fertility and Sterility. 116:e330
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ac63e578508fd292f00919d197a9e10
https://doi.org/10.1016/j.fertnstert.2021.07.891
https://doi.org/10.1016/j.fertnstert.2021.07.891