Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Michelle Møhlenberg"'
Publikováno v:
Yang, K, Guo, J, Møhlenberg, M & Zhou, H 2023, ' SARS-CoV-2 surveillance in medical and industrial wastewater-a global perspective : a narrative review ', Environmental Science and Pollution Research, vol. 30, no. 23, pp. 63323-63334 . https://doi.org/10.1007/s11356-023-26571-8
The novel coronavirus SARS-CoV-2 has spread at an unprecedented rate since late 2019, leading to the global COVID-19 pandemic. During the pandemic, being able to detect SARS-CoV-2 in human populations with high coverage quickly is a huge challenge. A
Publikováno v:
Møhlenberg, M, O’Brien, T R & Hartmann, R 2022, ' The role of IFNL4 in liver inflammation and progression of fibrosis ', Genes and Immunity, vol. 23, no. 3-4, pp. 111-117 . https://doi.org/10.1038/s41435-022-00173-9
The discovery that genetic variation within the interferon lambda locus has a profound effect on the outcome of hepatitis C virus (HCV) treatment and spontaneous clearance of HCV is one of the great triumphs of genomic medicine. Subsequently, the IFN
Publikováno v:
Wang, L, Møhlenberg, M, Wang, P & Zhou, H 2023, ' Immune evasion of neutralizing antibodies by SARS-CoV-2 Omicron ', Cytokine & Growth Factor Reviews, vol. 70, pp. 13-25 . https://doi.org/10.1016/j.cytogfr.2023.03.001
Since its emergence at the end of 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the infection of more than 600 million people worldwide and has significant damage to global medical, economic, and political structures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a6810171a928f3457c29e919329ad28
https://pure.au.dk/portal/da/publications/immune-evasion-of-neutralizing-antibodies-by-sarscov2-omicron(175ea71d-9458-4b3a-8dd5-4888223fcb20).html
https://pure.au.dk/portal/da/publications/immune-evasion-of-neutralizing-antibodies-by-sarscov2-omicron(175ea71d-9458-4b3a-8dd5-4888223fcb20).html
Autor:
Michelle Møhlenberg, Peter Lykke Eriksen, Tea Lund Laursen, Mette Bak Nielsen, Stephen Jacques Hamilton Dutoit, Henning Grønbæk, Rune Hartmann, Karen Louise Thomsen
Publikováno v:
Møhlenberg, M, Eriksen, P L, Laursen, T L, Nielsen, M B, Hamilton-Dutoit, S J, Grønbæk, H, Hartmann, R & Thomsen, K L 2022, ' The presence of interferon affects the progression of non-alcoholic fatty liver disease ', Genes and Immunity, vol. 23, no. 5, pp. 157–165 . https://doi.org/10.1038/s41435-022-00176-6
Inflammation and metabolic dysfunction are hallmarks of the progression of non-alcoholic fatty liver disease (NAFLD), which is the fastest-growing liver disease worldwide. Emerging evidence indicates that innate immune mechanisms are essential driver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e5212ef9ec61f8f3d2e88ebe0894f0b
https://pure.au.dk/portal/da/publications/the-presence-of-interferon-affects-the-progression-of-nonalcoholic-fatty-liver-disease(bdc6285f-2b0a-4fb2-bc61-d4d82f9305d6).html
https://pure.au.dk/portal/da/publications/the-presence-of-interferon-affects-the-progression-of-nonalcoholic-fatty-liver-disease(bdc6285f-2b0a-4fb2-bc61-d4d82f9305d6).html
Autor:
Hao Zhou, Michelle Møhlenberg, Jigarji C. Thakor, Hardeep Singh Tuli, Pengfei Wang, Yehuda G. Assaraf, Kuldeep Dhama, Shibo Jiang
Publikováno v:
Zhou, H, Møhlenberg, M, Thakor, J C, Tuli, H S, Wang, P, Assaraf, Y G, Dhama, K & Jiang, S 2022, ' Sensitivity to Vaccines, Therapeutic Antibodies, and Viral Entry Inhibitors and Advances To Counter the SARS-CoV-2 Omicron Variant ', Clinical Microbiology Reviews, vol. 35, no. 3, cmr.00014-22 . https://doi.org/10.1128/cmr.00014-22
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) keeps evolving and mutating into newer variants over time, which gain higher transmissibility, disease severity, and spread in communities at a faster rate, resulting in multiple waves of s
Autor:
Ole Schmeltz Søgaard, Stine S F Nielsen, Thomas R. O'Brien, Martin Tolstrup, Mariane H. Schleimann, Mads Kjolby, Ida Monrad, Giacomo S. Frattari, Line K. Vibholm, Michelle Møhlenberg, Jesper Damsgaard Gunst, Rikke Olesen, Rune Hartmann
Publikováno v:
Møhlenberg, M, Monrad, I, Vibholm, L K, Nielsen, S S F, Frattari, G S, Schleimann, M H, Olesen, R, Kjølby, M, Gunst, J D, Søgaard, O S, O'Brien, T R, Tolstrup, M & Hartmann, R 2021, ' The Impact of IFNλ4 on the Adaptive Immune Response to SARS-CoV-2 Infection ', Journal of Interferon & Cytokine Research, vol. 41, no. 11, pp. 407-414 . https://doi.org/10.1089/jir.2021.0106
J Interferon Cytokine Res
Møhlenberg, M, Monrad, I, Vibholm, L K, Nielsen, S S F, Frattari, G S, Schleimann, M H, Olesen, R, Kjolby, M, Gunst, J D, Søgaard, O S, O'Brien, T R, Tolstrup, M & Hartmann, R 2021, ' The Impact of IFNλ4 on the Adaptive Immune Response to SARS-CoV-2 Infection ', Journal of Interferon and Cytokine Research, vol. 41, no. 11, pp. 407-414 . https://doi.org/10.1089/jir.2021.0106
J Interferon Cytokine Res
Møhlenberg, M, Monrad, I, Vibholm, L K, Nielsen, S S F, Frattari, G S, Schleimann, M H, Olesen, R, Kjolby, M, Gunst, J D, Søgaard, O S, O'Brien, T R, Tolstrup, M & Hartmann, R 2021, ' The Impact of IFNλ4 on the Adaptive Immune Response to SARS-CoV-2 Infection ', Journal of Interferon and Cytokine Research, vol. 41, no. 11, pp. 407-414 . https://doi.org/10.1089/jir.2021.0106
Genetic polymorphisms at the IFNL4 loci are known to influence the clinical outcome of several different infectious diseases. Best described is the association between the IFNL4 genotype and hepatitis C virus clearance. However, an influence of the I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fbd5c74c21631c4acab331eea151b90
https://vbn.aau.dk/da/publications/b0e9df5a-d6fd-4e4c-a50e-ea6970a8ee34
https://vbn.aau.dk/da/publications/b0e9df5a-d6fd-4e4c-a50e-ea6970a8ee34
Autor:
Line S. Reinert, David Olagnier, Rune Hartmann, Jan J. Enghild, Jacob Thyrsted, Louise Dalskov, Michelle Møhlenberg, Hans Jürgen Hoffmann, Ebbe Toftgaard Poulsen, Søren Helbo Skaarup, Christian K. Holm, Julia Blay-Cadanet, Birgitte Holst Folkersen
Publikováno v:
Dalskov, L, Møhlenberg, M, Thyrsted, J, Blay-Cadanet, J, Poulsen, E T, Folkersen, B H, Skaarup, S H, Olagnier, D, Reinert, L, Enghild, J J, Hoffmann, H J, Holm, C K & Hartmann, R 2020, ' SARS-CoV-2 evades immune detection in alveolar macrophages ', EMBO Reports, vol. 21, no. 12, e51252 . https://doi.org/10.15252/embr.202051252
EMBO Reports
EMBO Reports
Respiratory infections, like the current COVID‐19 pandemic, target epithelial cells in the respiratory tract. Alveolar macrophages (AMs) are tissue‐resident macrophages located within the lung. They play a key role in the early phases of an immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58699028dd2de6427a7c8d16dd2fc9ed
https://pure.au.dk/portal/da/publications/sarscov2-evades-immune-detection-in-alveolar-macrophages(21d4f04d-d1d3-4007-b139-36bbc8b4568d).html
https://pure.au.dk/portal/da/publications/sarscov2-evades-immune-detection-in-alveolar-macrophages(21d4f04d-d1d3-4007-b139-36bbc8b4568d).html
Autor:
Ewa Terczyńska-Dyla, Nanna Hougaard Hansen, Anders Lade Nielsen, Rune Hartmann, Ronald Dijkman, Michelle Møhlenberg, Hans Henrik Gad, Laura Laloli, Hao Zhou, Kasper G. Winther, Johan Vad-Nielsen
Publikováno v:
Zhou, H, Møhlenberg, M, Terczyńska-Dyla, E, Winther, K G, Hansen, N H, Vad-Nielsen, J, Laloli, L, Dijkman, R, Nielsen, A L, Gad, H H & Hartmann, R 2020, ' The IFNL4 Gene Is a Noncanonical Interferon Gene with a Unique but Evolutionarily Conserved Regulation ', Journal of Virology, vol. 94, no. 5, pp. e01535-19 . https://doi.org/10.1128/JVI.01535-19
Zhou, Hao; Møhlenberg, Michelle; Terczyńska-Dyla, Ewa; Winther, Kasper Grønbjerg; Hansen, Nanna Hougaard; Vad-Nielsen, Johan; Laloli, Laura; Dijkman, Ronald; Nielsen, Anders Lade; Gad, Hans Henrik; Hartmann, Rune (2020). The IFNL4 gene is a non-canonical interferon gene with a unique but evolutionarily conserved regulation. Journal of virology, 94(5) American Society for Microbiology 10.1128/JVI.01535-19
Zhou, Hao; Møhlenberg, Michelle; Terczyńska-Dyla, Ewa; Winther, Kasper Grønbjerg; Hansen, Nanna Hougaard; Vad-Nielsen, Johan; Laloli, Laura; Dijkman, Ronald; Nielsen, Anders Lade; Gad, Hans Henrik; Hartmann, Rune (2020). The IFNL4 gene is a non-canonical interferon gene with a unique but evolutionarily conserved regulation. Journal of virology, 94(5) American Society for Microbiology 10.1128/JVI.01535-19
Interferon lambda 4 (IFN-λ4) is a recently identified enigmatic member of the interferon (IFN) lambda family. Genetic data suggest that the IFNL4 gene acts in a proviral and anti-inflammatory manner in patients. However, the protein is indistinguish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882d9cc8e9adf1bcbf4f2c8af55cd5c3
Autor:
Hao, Zhou, Michelle, Møhlenberg, Ewa, Terczyńska-Dyla, Kasper Grønbjerg, Winther, Nanna Hougaard, Hansen, Johan, Vad-Nielsen, Laura, Laloli, Ronald, Dijkman, Anders Lade, Nielsen, Hans Henrik, Gad, Rune, Hartmann
Publikováno v:
J Virol
Interferon lambda 4 (IFN-λ4) is a recently identified enigmatic member of the interferon (IFN) lambda family. Genetic data suggest that the IFNL4 gene acts in a proviral and anti-inflammatory manner in patients. However, the protein is indistinguish
Publikováno v:
Møhlenberg, M, Gad, H H & Hartmann, R 2019, ' The Influence of the rs30461 Single Nucleotide Polymorphism on IFN-l1 Activity and Secretion ' Journal of Interferon & Cytokine Research .
Møhlenberg, M, Gad, H H & Hartmann, R 2019, ' The Influence of the rs30461 Single Nucleotide Polymorphism on IFN-λ1 Activity and Secretion ', Journal of Interferon & Cytokine Research, vol. 39, no. 10, pp. 661-667 . https://doi.org/10.1089/jir.2019.0051
Møhlenberg, M, Gad, H H & Hartmann, R 2019, ' The Influence of the rs30461 Single Nucleotide Polymorphism on IFN-λ1 Activity and Secretion ', Journal of Interferon & Cytokine Research, vol. 39, no. 10, pp. 661-667 . https://doi.org/10.1089/jir.2019.0051
Genetic variation within the IFNL loci is associated with several diseases and evidence indicates that the IFNL genes have been subjects of strong selection during recent human evolution. The nonsynonymous rs30461 single nucleotide polymorphism (SNP)