Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Michelle M, Collins"'
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 9, Iss 1, p 13 (2022)
Cardiac arrhythmia, or irregular heart rhythm, is associated with morbidity and mortality and is described as one of the most important future public health challenges. Therefore, developing new models of cardiac arrhythmia is critical for understand
Externí odkaz:
https://doaj.org/article/81be4bdd1606495f9d492c5c453af62c
Autor:
Sébastien Gauvrit, Alethia Villasenor, Boris Strilic, Philip Kitchen, Michelle M. Collins, Rubén Marín-Juez, Stefan Guenther, Hans-Martin Maischein, Nana Fukuda, Maurice A. Canham, Joshua M. Brickman, Clifford W. Bogue, Padma-Sheela Jayaraman, Didier Y. R. Stainier
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
VEGFC, its receptor FLT4, and transcriptional effector PROX1 control formation of the lymphatic system but how is unclear. Here, the authors show that the transcription factor hematopoietically expressed homeobox (HHEX) regulates VEGFC, FLT4 and PROX
Externí odkaz:
https://doaj.org/article/3601d02f4c94462c8cb4148709279b67
Autor:
Manuel Vicente, Jussep Salgado-Almario, Michelle M. Collins, Antonio Martínez-Sielva, Masafumi Minoshima, Kazuya Kikuchi, Beatriz Domingo, Juan Llopis
Publikováno v:
Biomedicines, Vol 9, Iss 10, p 1294 (2021)
Zebrafish embryos and larvae have emerged as an excellent model in cardiovascular research and are amenable to live imaging with genetically encoded biosensors to study cardiac cell behaviours, including calcium dynamics. To monitor calcium ion level
Externí odkaz:
https://doaj.org/article/a69f151cb9d6462ba63580279f1eb6da
Correction: Loss of the Mia40a oxidoreductase leads to hepato-pancreatic insufficiency in zebrafish.
Autor:
Anna M Sokol, Barbara Uszczynska-Ratajczak, Michelle M Collins, Michal Bazala, Ulrike Topf, Pia R Lundegaard, Sreedevi Sugunan, Stefan Guenther, Carsten Kuenne, Johannes Graumann, Sherine S L Chan, Didier Y R Stainier, Agnieszka Chacinska
Publikováno v:
PLoS Genetics, Vol 15, Iss 1, p e1007972 (2019)
[This corrects the article DOI: 10.1371/journal.pgen.1007743.].
Externí odkaz:
https://doaj.org/article/7b73b7d754a74cebb5b5c4b59e3956f3
Autor:
Anna M Sokol, Barbara Uszczynska-Ratajczak, Michelle M Collins, Michal Bazala, Ulrike Topf, Pia R Lundegaard, Sreedevi Sugunan, Stefan Guenther, Carsten Kuenne, Johannes Graumann, Sherine S L Chan, Didier Y R Stainier, Agnieszka Chacinska
Publikováno v:
PLoS Genetics, Vol 14, Iss 11, p e1007743 (2018)
Development and function of tissues and organs are powered by the activity of mitochondria. In humans, inherited genetic mutations that lead to progressive mitochondrial pathology often manifest during infancy and can lead to death, reflecting the in
Externí odkaz:
https://doaj.org/article/23383a47843e48fcb904a69659560535
Autor:
Michelle M Collins, Hans-Martin Maischein, Pascale Dufourcq, Marine Charpentier, Patrick Blader, Didier YR Stainier
Publikováno v:
eLife, Vol 7 (2018)
Pitx2c, a homeodomain transcription factor, is classically known for its left-right patterning role. However, an early wave of pitx2 expression occurs at the onset of gastrulation in several species, indicating a possible earlier role that remains re
Externí odkaz:
https://doaj.org/article/81769231a235401ebcf627e31dd2e6a3
Autor:
Manuel Vicente, Jussep Salgado-Almario, Ariel A. Valiente-Gabioud, Michelle M. Collins, Pierre Vincent, Beatriz Domingo, Juan Llopis
Publikováno v:
Journal of molecular and cellular cardiology. 173
The phospholamban mutation Arg 9 to Cys (R9C) has been found to cause a dilated cardiomyopathy in humans and in transgenic mice, with ventricular dilation and premature death. Emerging evidence suggests that phospholamban R9C is a loss-of-function mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b301cfd42b5646bc388534a0e1726f1
https://pubmed.ncbi.nlm.nih.gov/36273660
https://pubmed.ncbi.nlm.nih.gov/36273660
Publikováno v:
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease, Vol 9, Iss 13, p 13 (2022)
Journal of Cardiovascular Development and Disease, Vol 9, Iss 13, p 13 (2022)
Cardiac arrhythmia, or irregular heart rhythm, is associated with morbidity and mortality and is described as one of the most important future public health challenges. Therefore, developing new models of cardiac arrhythmia is critical for understand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b9a770fb5dec17e0056aa11300e91f4
https://pubmed.ncbi.nlm.nih.gov/35050223
https://pubmed.ncbi.nlm.nih.gov/35050223
Autor:
Stefan Guenther, Gustav Ahlberg, Rubén Marín-Juez, Hadil El-Sammak, Ylva Hellsten, Janett Piesker, Camilla Vestergaard Hansen, Pia R. Lundegaard, Anna M. Sokol, Didier Y.R. Stainier, Morten S. Olesen, Michelle M. Collins
Publikováno v:
Proceedings of the National Academy of Sciences. 116:24115-24121
Atrial fibrillation (AF) is the most common type of cardiac arrhythmia. The major AF susceptibility locus 4q25 establishes long-range interactions with the promoter of PITX2 , a transcription factor gene with critical functions during cardiac develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19279ee4599d38ced4dd671eaaf5c329
https://doi.org/10.1073/pnas.1913905116
https://doi.org/10.1073/pnas.1913905116
Autor:
Manuel Vicente, Juan Llopis, Kazuya Kikuchi, Michelle M. Collins, Masafumi Minoshima, Antonio Martínez-Sielva, Jussep Salgado-Almario, Beatriz Domingo
The zebrafish embryo has emerged as an excellent model in cardiovascular research. The existing techniques to monitor Ca2+ in the heart based on fluorescent Ca2+ biosensors are limited due to phototoxicity and photobleaching. To overcome these issues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f410ee42a21619c4bc4524a4d847b6c
https://doi.org/10.1101/2021.05.06.442917
https://doi.org/10.1101/2021.05.06.442917
