Výsledky vyhledávání - "Michelle Lesimple"

Xenopus as a model to study alternative splicing in vivo

Autor: Agnès Méreau, Serge Hardy, Michelle Lesimple, Hubert Lerivray, Caroline Le Sommer

Publikováno v: Biology of the Cell. 99:55-65

An increasing number of genes are being identified for which the corresponding mRNAs contain different combinations of the encoded exons. This highly regulated exon choice, or alternative splicing, is often tissue-specific and potentially could diffe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b330cd3d558446e7553e38b369e64ec5
https://doi.org/10.1042/bc20060073

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Oligomerization of EDEN-BP is required for specific mRNA deadenylation and binding

Autor: Bertrand Cosson, Ounissa Aït-Ahmed, Michelle Lesimple, Carole Gautier-Courteille, Luc Paillard, Dominique Maniey, H. Beverley Osborne

Publikováno v: Biology of the Cell
Biology of the Cell, Wiley, 2006, 98 (11), pp.653-65. ⟨10.1042/BC20060054⟩
Biology of the Cell, 2006, 98 (11), pp.653-65. ⟨10.1042/BC20060054⟩

International audience; BACKGROUND INFORMATION: mRNA deadenylation [shortening of the poly(A) tail] is often triggered by specific sequence elements present within mRNA 3' untranslated regions and generally causes rapid degradation of the mRNA. In ve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2645ad072f3042a45795d8b5138cd51b
https://doi.org/10.1042/bc20060054

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Alternative Splicing of Xenopus αfast-Tropomyosin Pre-mRNA during Development: Identification of Determining Sequences

Autor: Serge Hardy, Patrick Duriez, Michelle Lesimple, Marie-Rose Allo

Publikováno v: DNA and Cell Biology. 19:365-376

The Xenopus alphafast-tropomyosin gene contains in its central part a set of mutually exclusive exons, designated 6A and 6B, which are incorporated into mRNA encoding, respectively, nonmuscle and muscle tropomyosins. In this study, we show that usage

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d46e5f59a8b3946ec5e038803e9cb939
https://doi.org/10.1089/10445490050043335

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PTB regulates the processing of a 3'-terminal exon by repressing both splicing and polyadenylation

Autor: Agnès Méreau, Serge Hardy, Severine Menoret, Michelle Lesimple, Caroline Le Sommer, Marie-Rose Allo

Publikováno v: Molecular and Cellular Biology
Molecular and Cellular Biology, American Society for Microbiology, 2005, 25 (21), pp.9595-9607. ⟨10.1128/MCB.25.21.9595-9607.2005⟩
Molecular and Cellular Biology, 2005, 25 (21), pp.9595-9607. ⟨10.1128/MCB.25.21.9595-9607.2005⟩

International audience; The polypyrimidine tract binding protein (PTB) has been described as a global repressor of regulated exons. To investigate PTB functions in a physiological context, we used a combination of morpholino-mediated knockdown and tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fde93580c3dcf835f3d57434a556503
https://pubmed.ncbi.nlm.nih.gov/16227608

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Melanin as a natural germ cell marker for intraspecific transplantation experiments in Ambystoma mexicanum (Urodela, Amphibia)

Autor: Charles Houillon, Christian Dournon, Michelle Lesimple

Publikováno v: Roux's archives of developmental biology : the official organ of the EDBO. 198(7)

In urodele amphibians, the lack of a reliable germ cell marker restricts the experimental study of the germ lineage. In the present work, we conducted genetic and histological analyses in order to demonstrate that melanin from oocytes constitutes a g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::686eb0f80d3cb492b912d76d0c373e79
https://pubmed.ncbi.nlm.nih.gov/28305537

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