Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Michelle L. Wiese"'
Autor:
Efstathios Karathanasis, Christopher J. Hoimes, Gil Covarrubias, Amy L. Goldberg, Michelle L. Wiese, Peter A. Bielecki, Carolyn Zheng, Taylor J. Moon, Vanitha Raguveer, Shruti P. Raghunathan, Prabhani U. Atukorale
Effective cancer immunotherapy depends on the robust activation of tumor-specific antigen-presenting cells (APC). Immune agonists encapsulated within nanoparticles (NP) can be delivered to tumor sites to generate powerful antitumor immune responses w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d953fd927d7e3365101de9fd76746975
https://doi.org/10.1158/0008-5472.c.6510899.v1
https://doi.org/10.1158/0008-5472.c.6510899.v1
Autor:
Efstathios Karathanasis, Christopher J. Hoimes, Gil Covarrubias, Amy L. Goldberg, Michelle L. Wiese, Peter A. Bielecki, Carolyn Zheng, Taylor J. Moon, Vanitha Raguveer, Shruti P. Raghunathan, Prabhani U. Atukorale
SF1: IFNβ production from macrophages by ELISA analysis; SF2: FMT imaging of mammary tumors ex vivo for spatial localization of nanoparticle; SF3: Confocal micrographs of DiI-nanoparticle fluorescence in mammary tumor tissue; SF4: Representative ima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aac2c80a944bc3fbbcbba0278e2bdaf8
https://doi.org/10.1158/0008-5472.22421333
https://doi.org/10.1158/0008-5472.22421333
Autor:
Gil Covarrubias, Taylor J. Moon, Shruthi Ravichandran, Efstathios Karathanasis, Prabhani U. Atukorale, Peter Bielecki, Michelle L. Wiese, Morgan E Lorkowski, Yahan Zhang, Wyatt M. Becicka
Publikováno v:
Nanoscale Horiz
The high mortality associated with glioblastoma multiforme (GBM) is attributed to its invasive nature, hypoxic core, resistant cell subpopulations and a highly immunosuppressive tumor microenvironment (TME). To support adaptive immune function and es
Autor:
Mayura P Umapathy, Gil Covarrubias, Morgan E Lorkowski, Taylor J. Moon, Prabhani U. Atukorale, Georgia Loutrianakis, Haley M. Sims, Michelle L. Wiese, Efstathios Karathanasis, Peter Bielecki
Publikováno v:
J Mater Chem B
To alter the immunosuppressive tumor microenvironment (TME), we developed an immunostimulatory nanoparticle (NP) to reprogram a tumor’s dysfunctional and inhibitory antigen-presenting cells (APCs) into properly activated APCs that stimulate tumor-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef0b7261985c46e73d2c9810600885e7
https://europepmc.org/articles/PMC8732314/
https://europepmc.org/articles/PMC8732314/
Autor:
S. Raghunathan, Gil Covarrubias, Efstathios Karathanasis, Taylor J. Moon, Carolyn Zheng, Peter Bielecki, Vanitha Raguveer, Christopher J. Hoimes, Amy Goldberg, Michelle L. Wiese, Prabhani U. Atukorale
Publikováno v:
Cancer Research. 79:5394-5406
Effective cancer immunotherapy depends on the robust activation of tumor-specific antigen-presenting cells (APC). Immune agonists encapsulated within nanoparticles (NP) can be delivered to tumor sites to generate powerful antitumor immune responses w
Autor:
Christopher Hernandez, Peter Bielecki, Michael C. Kolios, Chawan Manaspon, Michelle L. Wiese, Agata A. Exner, Selva Jeganathan
Publikováno v:
2017 IEEE International Ultrasonics Symposium (IUS).
In situ forming implants (ISFIs) can provide continuous, high dose release of chemotherapeutic drug directly at the tumor site. However, poor drug distribution through the tumor volume has limited the effectiveness and subsequent translation of ISFIs