Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Michelle L. Nieman"'
Autor:
Valeria Rudman-Melnick, Mike Adam, Kaitlynn Stowers, Andrew Potter, Qing Ma, Saagar M. Chokshi, Davy Vanhoutte, Iñigo Valiente-Alandi, Diana M. Lindquist, Michelle L. Nieman, J. Matthew Kofron, Eunah Chung, Joo-Seop Park, S. Steven Potter, Prasad Devarajan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Examining kidney fibrosis is crucial for mechanistic understanding and developing targeted strategies against chronic kidney disease (CKD). Persistent fibroblast activation and tubular epithelial cell (TEC) injury are key CKD contributors. H
Externí odkaz:
https://doaj.org/article/fb7e56c701184434a55c7bc914d1b4b2
Autor:
Lisa C, Green, Samuel, Slone, Sarah R, Anthony, Adrienne R, Guarnieri, Sharon, Parkins, Shannon M, Shearer, Michelle L, Nieman, Sudeshna, Roy, Jeffrey, Aube, Xiaoqing, Wu, Liang, Xu, Onur, Kanisicak, Michael, Tranter
Publikováno v:
Journal of Molecular and Cellular Cardiology. 174:38-46
Cardiac fibrosis is regulated by the activation and phenotypic switching of quiescent cardiac fibroblasts to active myofibroblasts, which have extracellular matrix (ECM) remodeling and contractile functions which play a central role in cardiac remode
Autor:
Valeria Rudman-Melnick, Mike Adam, Kaitlynn Stowers, Andrew Potter, Qing Ma, Saagar M. Chokshi, Davy Vanhoutte, Iñigo Valiente-Alandi, Diana M. Lindquist, Michelle L. Nieman, J. Matthew Kofron, S. Steven Potter, Prasad Devarajan
Examining kidney fibrosis is crucial for mechanistic understanding and developing targeted strategies against chronic kidney disease (CKD). Persistent fibroblast activation and tubular epithelial cell (TEC) injury are key CKD contributors. However, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34ae0cac9de9cdfb10012822221312a6
https://doi.org/10.21203/rs.3.rs-2880248/v1
https://doi.org/10.21203/rs.3.rs-2880248/v1
Autor:
Samuel Slone, Sarah R. Anthony, Lisa C. Green, Michelle L. Nieman, Perwez Alam, Xiaoqing Wu, Sudeshna Roy, Jeffrey Aube, Liang Xu, John N. Lorenz, A. Phillip Owens, Onur Kanisicak, Michael Tranter
Publikováno v:
bioRxiv
Myocardial ischemia/reperfusion (I/R) injury and the resulting cardiac remodeling is a common cause of heart failure. The RNA binding protein Human Antigen R (HuR) has been previously shown to reduce cardiac remodeling following both I/R and cardiac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c616617f797378b82d427a86bdf37bc
https://europepmc.org/articles/PMC9882229/
https://europepmc.org/articles/PMC9882229/
Autor:
Valeria Rudman-Melnick, Mike Adam, Kaitlynn Stowers, Andrew Potter, Qing Ma, Saagar M. Chokshi, Davy Vanhoutte, Iñigo Valiente-Alandi, Diana M. Lindquist, Michelle L. Nieman, J. Matthew Kofron, S. Steven Potter, Prasad Devarajan
BackgroundPersistent kidney fibroblast activation and tubular epithelial cell (TEC) injury are key contributors to CKD. However, transcriptional and cellular identities of advanced kidney disease, along with renal fibroblast specific markers and mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::081114116264b19b5592988c995238a5
https://doi.org/10.1101/2022.09.13.507855
https://doi.org/10.1101/2022.09.13.507855
Autor:
Parvathi Mudigonda, John N. Lorenz, Jack Rubinstein, Michelle L. Nieman, Sheryl E. Koch, Nathan Robbins, Ranjani Ramasubramanian, Felix Karthik, Akiva Kirschner
Publikováno v:
Cardiovascular Toxicology. 21:889-900
Complete vascular occlusion to distant tissue prior to an ischemic cardiac event can provide significant cardioprotection via remote ischemic preconditioning (RIPC). Despite understanding its mechanistic basis, its translation to clinical practice ha
Autor:
Richard J. Gilbert, Thomas C. Irving, David M. Warshaw, Sakthivel Sadayappan, Weikang Ma, James W. McNamara, Gina Kuffel, Mayandi Sivaguru, Diederik W. D. Kuster, Paul M.L. Janssen, Burns C. Blaxall, Mohit Kumar, Dana M. Leichter, John N. Lorenz, Kyounghwan Lee, Michael J. Previs, Roger Craig, Michelle L. Nieman, Brian Lin, Thomas L. Lynch, Rohit R. Singh, Pieter P. de Tombe, Aaron M. Gibson, Michael J. Zilliox, Owen P. Leary
Publikováno v:
Lynch, T L, Kumar, M, McNamara, J W, Kuster, D W D, Sivaguru, M, Singh, R R, Previs, M J, Lee, K H, Kuffel, G, Zilliox, M J, Lin, B L, Ma, W, Gibson, A M, Blaxall, B C, Nieman, M L, Lorenz, J N, Leichter, D M, Leary, O P, Janssen, P M L, de Tombe, P P, Gilbert, R J, Craig, R, Irving, T, Warshaw, D M & Sadayappan, S 2021, ' Amino terminus of cardiac myosin binding protein-C regulates cardiac contractility ', Journal of Molecular and Cellular Cardiology, vol. 156, pp. 33-44 . https://doi.org/10.1016/j.yjmcc.2021.03.009
Journal of Molecular and Cellular Cardiology
Journal of Molecular and Cellular Cardiology, Elsevier, 2021, 156, pp.33-44. ⟨10.1016/j.yjmcc.2021.03.009⟩
J Mol Cell Cardiol
Journal of Molecular and Cellular Cardiology, 156, 33-44. Academic Press Inc.
Journal of Molecular and Cellular Cardiology
Journal of Molecular and Cellular Cardiology, Elsevier, 2021, 156, pp.33-44. ⟨10.1016/j.yjmcc.2021.03.009⟩
J Mol Cell Cardiol
Journal of Molecular and Cellular Cardiology, 156, 33-44. Academic Press Inc.
International audience; Phosphorylation of cardiac myosin binding protein-C (cMyBP-C) regulates cardiac contraction through modulation of actomyosin interactions mediated by the protein's amino terminal (N′)-region (C0-C2 domains, 358 amino acids).
Autor:
Joshua B. Benoit, Lisa C. Green, Perwez Alam, Salma M Fleifil, Michelle L. Nieman, Onur Kanisicak, A. Phillip Owens, Sam Slone, Anamarie Gozdiff, Michael Tranter, Adrienne R Guarnieri, Sarah R. Anthony
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 321:H228-H241
Adipose tissue homeostasis plays a central role in cardiovascular physiology, and the presence of thermogenically active brown adipose tissue (BAT) has recently been associated with cardiometabolic health. We have previously shown that adipose tissue
Autor:
Sarah R. Anthony, Adrienne R. Guarnieri, Lisa C. Green, Sam Slone, Michelle L. Nieman, A. P. Owens, Onur Kanisicak, Michael Tranter
Publikováno v:
The FASEB Journal. 36
Autor:
Akiva, Kirschner, Sheryl E, Koch, Nathan, Robbins, Felix, Karthik, Parvathi, Mudigonda, Ranjani, Ramasubramanian, Michelle L, Nieman, John N, Lorenz, Jack, Rubinstein
Publikováno v:
Cardiovascular toxicology. 21(11)
Complete vascular occlusion to distant tissue prior to an ischemic cardiac event can provide significant cardioprotection via remote ischemic preconditioning (RIPC). Despite understanding its mechanistic basis, its translation to clinical practice ha