Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Michelle L. Dubuke"'
Autor:
Reka Agnes Haraszti, Rachael Miller, Michelle L. Dubuke, Hannah E. Rockwell, Andrew H. Coles, Ellen Sapp, Marie-Cecile Didiot, Dimas Echeverria, Matteo Stoppato, Yves Y. Sere, John Leszyk, Julia F. Alterman, Bruno M.D.C. Godinho, Matthew R. Hassler, Justice McDaniel, Niven R. Narain, Rachel Wollacott, Yang Wang, Scott A. Shaffer, Michael A. Kiebish, Marian DiFiglia, Neil Aronin, Anastasia Khvorova
Publikováno v:
iScience, Vol 16, Iss , Pp 230-241 (2019)
Summary: Exosomes can serve as delivery vehicles for advanced therapeutics. The components necessary and sufficient to support exosomal delivery have not been established. Here we connect biochemical composition and activity of exosomes to optimize e
Externí odkaz:
https://doaj.org/article/21894a18485a4c49a1a72ee7b538a0ae
Autor:
Luis Vidali, Allison M. Butt, Fabienne Furt, Mary Munson, Sarah E. Cabral, Robert G. Orr, Jennifer M. Garbarino, Erin L. Warner, Michelle L. Dubuke, Erin M. Agar
Publikováno v:
New Phytol
The fundamental process of polarised exocytosis requires the interconnected activity of molecular motors trafficking vesicular cargo within a dynamic cytoskeletal network. In plants, few mechanistic details are known about how molecular motors, such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c746d2d2b426b259e73d76a8ea9a546d
https://doi.org/10.1111/nph.17023
https://doi.org/10.1111/nph.17023
Autor:
Kristin S. Koutmou, Yury S. Polikanov, Daniel E. Eyler, Malgorzata Dobosz-Bartoszek, Bijoyita Roy, Monika K Franco, Joshua D. Jones, Zahra Batool, Monica Z. Wu, Michelle L. Dubuke
Publikováno v:
Proc Natl Acad Sci U S A
Chemical modifications of RNAs have long been established as key modulators of nonprotein-coding RNA structure and function in cells. There is a growing appreciation that messenger RNA (mRNA) sequences responsible for directing protein synthesis can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d9f11d9e478d8c9f5d3f9c3e4a40f2
https://doi.org/10.1073/pnas.1821754116
https://doi.org/10.1073/pnas.1821754116
Autor:
Niven R. Narain, Scott A. Shaffer, Justice McDaniel, Reka A. Haraszti, Andrew H. Coles, Anastasia Khvorova, Bruno M.D.C. Godinho, Yang Wang, Matteo Stoppato, Dimas Echeverria, John D. Leszyk, Michelle L. Dubuke, Ellen Sapp, Neil Aronin, Rachel Wollacott, Rachael Miller, Matthew R. Hassler, Marie-Cecile Didiot, Hannah E. Rockwell, Julia F. Alterman, Michael A. Kiebish, Yves Y. Sere, Marian DiFiglia
Publikováno v:
iScience, Vol 16, Iss, Pp 230-241 (2019)
iScience
iScience
Summary Exosomes can serve as delivery vehicles for advanced therapeutics. The components necessary and sufficient to support exosomal delivery have not been established. Here we connect biochemical composition and activity of exosomes to optimize ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f78d0578af3bd8e15c0391169838ad5
http://www.sciencedirect.com/science/article/pii/S258900421930166X
http://www.sciencedirect.com/science/article/pii/S258900421930166X
Autor:
Yanglan Tan, Kristina M. Deligiannidis, Michelle L. Dubuke, Aimee R. Kroll-Desrosiers, Scott A. Shaffer
Publikováno v:
Psychoneuroendocrinology
BACKGROUND: Neuroactive steroids (NAS) are derivatives of cholesterol or steroidal precursors made in the gonads, adrenal gland, placenta and brain. We characterized longitudinal plasma proneuroactive and NAS in healthy perinatal comparison women (HP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2b8e82f9078261b5d877a5bd1db731c
https://pubmed.ncbi.nlm.nih.gov/32828068
https://pubmed.ncbi.nlm.nih.gov/32828068
Autor:
Maxwell Robidoux, Guillaume L. Poirier, Marcelo Febo, Luis M. Colon-Perez, Michelle L. Dubuke, Matthew B. Thompson, Joseph R. DiFranza, Martha I. Dávila-García, Jean A. King, Kelly Tam, Wei Huang, Scott A. Shaffer
Publikováno v:
Journal of Psychopharmacology. 32:332-343
Mentholated cigarettes capture a quarter of the US market, and are disproportionately smoked by adolescents. Menthol allosterically modulates nicotinic acetylcholine receptor function, but its effects on the brain and nicotine addiction are unclear.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7f4c56e50043c2d4c91b52a0725f77
https://doi.org/10.1177/0269881117719265
https://doi.org/10.1177/0269881117719265
Autor:
Erin L. Warner, Luis Vidali, Erin M. Agar, Mary Munson, Sarah E. Cabral, Jennifer M. Garbarino, Allison M. Butt, Michelle L. Dubuke, Fabienne Furt, Robert G. Orr
The fundamental eukaryotic process of intracellular trafficking requires the interconnected activity of molecular motors trafficking vesicular cargo within a dynamic cytoskeletal network. However, in plants, few mechanistic details are known about ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1edcdc155cf792bd47d936d0be9d38a
https://doi.org/10.1101/617167
https://doi.org/10.1101/617167
Autor:
Michelle L. Dubuke, Mariana J. Kaplan, A. J. Maurais, Scott A. Shaffer, Carmelo Carmona-Rivera, Paul R. Thompson, Ari J. Salinger, Eranthie Weerapana
Publikováno v:
Sci Immunol
Rheumatoid arthritis (RA) is characterized by synovial joint inflammation and by development of pathogenic humoral and cellular autoimmunity to citrullinated proteins. Neutrophil extracellular traps (NETs) are a source of citrullinated autoantigens a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d35be0574a2e97f0c12de7541b091d23
https://pubmed.ncbi.nlm.nih.gov/28649674
https://pubmed.ncbi.nlm.nih.gov/28649674
Autor:
Scott A. Shaffer, Anastasia Khvorova, Yang Wang, Neil Aronin, Marian DiFiglia, Andrew H. Coles, Rachel Wollacott, Xuni Li, Marie-Cecile Didiot, Yves Y. Sere, Matteo Stoppato, Ellen Sapp, Reka A. Haraszti, Rachael Miller, Michelle L. Dubuke
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 26(12)
Exosomes can deliver therapeutic RNAs to neurons. The composition and the safety profile of exosomes depend on the type of the exosome-producing cell. Mesenchymal stem cells are considered to be an attractive cell type for therapeutic exosome product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020232ec61c7e38acf0c18a3ee11782c
https://pubmed.ncbi.nlm.nih.gov/30341012
https://pubmed.ncbi.nlm.nih.gov/30341012
Publikováno v:
Journal of Biological Chemistry. 290:28245-28256
In eukaryotic cells, membrane-bound vesicles carry cargo between intracellular compartments, to and from the cell surface, and into the extracellular environment. Many conserved families of proteins are required for properly localized vesicle fusion,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce6d79b164b398087af13bc7890caf3b
https://doi.org/10.1074/jbc.m115.673806
https://doi.org/10.1074/jbc.m115.673806