Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Michelle L. Cunningham"'
Publikováno v:
Nature Reviews Neuroscience. 5:657-661
The study of the nervous system draws from many disciplines, including biology, chemistry, medicine, psychology and engineering. A consequence of this interdisciplinary approach is that discoveries in one discipline can inform and supplement other di
Publikováno v:
Journal of Biological Chemistry. 276:5438-5444
RGS proteins (regulators of G protein signaling) attenuate heterotrimeric G protein signaling by functioning as both GTPase-activating proteins (GAPs) and inhibitors of G protein/effector interaction. RGS2 has been shown to regulate Galpha(q)-mediate
Publikováno v:
Biochemical Journal. 338:257-264
The potential role of protein kinase C (PKC)-promoted phosphorylation has been examined in the G-protein-regulated inositol lipid signalling pathway. Incubation of [32P]Pi-labelled turkey erythrocytes with either the P2Y1 receptor agonist 2-methylthi
Autor:
Sheritha P. Lee, Michelle L. Cunningham, Patrick C. Hines, Christopher C. Joneckis, Eugene P. Orringer, Leslie V. Parise
Publikováno v:
Blood. 92:2951-2958
Sickle red blood cell (RBC) adhesion to the endothelium and to exposed, underlying subendothelial proteins is believed to contribute to vascular occlusion in sickle cell disease. Laminin, a major component of the subendothelium, supports significant
Autor:
Sheritha P. Lee, Eugene P. Orringer, Christopher C. Joneckis, Michelle L. Cunningham, Leslie V. Parise, Patrick C. Hines
Publikováno v:
Blood. 92:2951-2958
Sickle red blood cell (RBC) adhesion to the endothelium and to exposed, underlying subendothelial proteins is believed to contribute to vascular occlusion in sickle cell disease. Laminin, a major component of the subendothelium, supports significant
Autor:
Leslie V. Parise, Michelle L. Cunningham, Christopher C. Joneckis, David D. Shock, Eugene P. Orringer
Publikováno v:
Blood. 87:4862-4870
The abnormal adherence of red blood cells (RBC to the blood vessel wall is believed to contribute to the vascular occlusion observed in patients with sickle call anemia. The cell adhesion receptors GPIV (CD36) and integrin alpha 4 beta 1 (CD49d/CD29)
Publikováno v:
Molecular pharmacology. 56(2)
The effects of protein kinase C (PKC) activation on inositol lipid signaling were examined. Using the turkey erythrocyte model of receptor-regulated phosphoinositide hydrolysis, we developed a membrane reconstitution assay to study directly the effec