Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Michelle L. Manni"'
Autor:
Yu Zhang, Jiuyang Xu, Margot Miranda-Katz, Jorna Sojati, Sharon J Tollefson, Michelle L Manni, John F Alcorn, Saumendra N Sarkar, John V Williams
Publikováno v:
PLoS Pathogens, Vol 20, Iss 2, p e1011840 (2024)
Human metapneumovirus (HMPV) is an important cause of acute lower respiratory infection in children and adults worldwide. There are four genetic subgroups of HMPV and both neutralizing antibodies and T cells contribute to protection. However, little
Externí odkaz:
https://doaj.org/article/6c53634f17784f9eb5425badd0b949ab
Autor:
Victoria A. Heinrich, Crystal Uvalle, Michelle L. Manni, Kelvin Li, Steven J. Mullett, Sri Ramya Donepudi, Jason Clader, Adam Fitch, Madeline Ellgass, Veronika Cechova, Shulin Qin, Fernando Holguin, Bruce A. Freeman, Barbara A. Methé, Alison Morris, Stacy L. Gelhaus
Publikováno v:
Frontiers in Microbiomes, Vol 2 (2023)
Obesity and associated changes to the gut microbiome worsen airway inflammation and hyperresponsiveness in asthma. Obesogenic host-microbial metabolomes have altered production of metabolites that may influence lung function and inflammatory response
Externí odkaz:
https://doaj.org/article/ca9aa240e77746a392708e4e1d31ec30
Autor:
Michelle L. Manni, Victoria A. Heinrich, Gregory J. Buchan, James P. O’Brien, Crystal Uvalle, Veronika Cechova, Adolf Koudelka, Dharti Ukani, Mohamad Rawas-Qalaji, Tim D. Oury, Renee Hart, Madeline Ellgass, Steven J. Mullett, Merritt L. Fajt, Sally E. Wenzel, Fernando Holguin, Bruce A. Freeman, Stacy G. Wendell
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Bile acid profiles are altered in obese individuals with asthma. Thus, we sought to better understand how obesity-related systemic changes contribute to lung pathophysiology. We also test the therapeutic potential of nitro-oleic acid (NO2-OA
Externí odkaz:
https://doaj.org/article/40111bfc71bc4fc1b5f339c0101d5c5d
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Asthma is a highly prevalent, chronic respiratory disease that impacts millions of people worldwide and causes thousands of deaths every year. Asthmatics display different phenotypes with distinct genetic components, environmental causes, and immunop
Externí odkaz:
https://doaj.org/article/c6ed1f71163340b8906ff507c432fe6d
Autor:
Radha Gopal, Benjamin Lee, Kevin J. McHugh, Helen E. Rich, Krishnaveni Ramanan, Sivanarayana Mandalapu, Michelle E. Clay, Philip J. Seger, Richard I. Enelow, Michelle L. Manni, Keven M. Robinson, Javier Rangel-Moreno, John F. Alcorn
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Influenza is a common respiratory virus that infects between 5 and 20% of the US population and results in 30,000 deaths annually. A primary cause of influenza-associated death is secondary bacterial pneumonia. We have previously shown that influenza
Externí odkaz:
https://doaj.org/article/c296759483a54f1c982c9edb7a45130c
Autor:
Zhongli Xu, Erick Forno, Edna Acosta‐Pérez, Yueh‐Ying Han, Franziska Rosser, Michelle L. Manni, Glorisa Canino, Wei Chen, Juan C. Celedón
Publikováno v:
Pediatr Allergy Immunol
BACKGROUND: The mechanisms underlying the known link between overweight/obesity and childhood asthma are unclear. We aimed to identify differentially expressed genes and pathways associated with obesity-related asthma through a transcriptomic analysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e751a2825af4ef748cd693f70f2293ea
https://pubmed.ncbi.nlm.nih.gov/35871458
https://pubmed.ncbi.nlm.nih.gov/35871458
Autor:
Veronika Cechova, Bruce A. Freeman, James P. O’Brien, Sally E. Wenzel, Adolf Koudelka, Victoria A. Heinrich, Michelle L. Manni, Madeline Ellgass, Steven J. Mullett, Renee Hart, Merritt L. Fajt, Fernando Holguin, Mohamad Rawas-Qalaji, Dharti Ukani, Stacy G. Wendell, Gregory J. Buchan, Crystal E. Uvalle, Tim D. Oury
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Bile acid profiles are altered in obese individuals with asthma. Thus, we sought to better understand how obesity-related systemic changes contribute to lung pathophysiology. We also test the therapeutic potential of nitro-oleic acid (NO2-OA), a regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cf4f662f4996e9736d778de44d7f871
https://doi.org/10.1038/s41598-021-96471-9
https://doi.org/10.1038/s41598-021-96471-9
Autor:
Selma F. Witchel, Edna Acosta-Pérez, Glorisa Canino, Erick Forno, Michelle L. Manni, Yueh-Ying Han, Juan C. Celedón
Publikováno v:
TP65. TP065 ENVIRONMENTAL EXPOSURES AND LUNG DISEASE.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c45fbb47d197d2f5678e006c1645ea2e
https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a3119
https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a3119
Autor:
Marianna A. Ortiz, Keven M. Robinson, Kevin J. McHugh, Robert N. Abood, Derek Pociask, Joshua M. Tobin, John F. Alcorn, Michelle L. Manni, Helen E. Rich, Jay K. Kolls, Jennifer M. Bomberger, Krishnaveni Ramanan
Publikováno v:
Mucosal immunology
Secondary bacterial pneumonia is a significant complication of severe influenza infection and Staphylococcus aureus and Streptococcus pneumoniae are the primary pathogens of interest. IL-22 promotes S. aureus and S. pneumoniae host defense in the lun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::918643b781c482b0043143d9d5cb69e3
https://doi.org/10.1038/s41385-019-0188-7
https://doi.org/10.1038/s41385-019-0188-7
Autor:
Michelle L Manni, Victoria A Heinrich, Crystal E Uvalle, Allison Manuel, Madeline R Ellgass, Steven J Mullett, Marigny C Normann, Corrine Koziel, Merritt L Fajt, Sally E Wenzel, Fernando Holguin, Bruce A Freeman, Stacy L Wendell
Publikováno v:
The Journal of Immunology. 208:109.10-109.10
Obesity-associated asthma is phenotypically characterized by low grade inflammation and resistance to standard therapies. Like many other asthma endotypes, the molecular mechanisms contributing to obesity-associated asthma are diverse and ambiguous.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb0fadb744e2f1b8d9f6339c6379892e
https://doi.org/10.4049/jimmunol.208.supp.109.10
https://doi.org/10.4049/jimmunol.208.supp.109.10