Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Michelle L Villemaire"'
Autor:
Charlene M Downey, Arvind K Singla, Michelle L Villemaire, Helen R Buie, Steven K Boyd, Frank R Jirik
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41685 (2012)
Techniques for visualizing and quantifying the microvasculature of tumors are essential not only for studying angiogenic processes but also for monitoring the effects of anti-angiogenic treatments. Given the relatively limited information that can be
Externí odkaz:
https://doaj.org/article/3118dd24489d4287b41782de0547d9cd
Autor:
H Artee Luchman, Hallgrimur Benediktsson, Michelle L Villemaire, Alan C Peterson, Frank R Jirik
Publikováno v:
PLoS ONE, Vol 3, Iss 12, p e3940 (2008)
Loss of the PTEN tumor suppressor is a common occurrence in human prostate cancer, particularly in advanced disease. In keeping with its role as a pivotal upstream regulator of the phosphatidylinositol 3-kinase signaling pathway, experimentally-induc
Externí odkaz:
https://doaj.org/article/9dd8169e4c7846748f9dd1c1b69bc4da
Autor:
Frank R. Jirik, Michelle L. Villemaire, Bradley A. Carlson, H. Artee Luchman, Tarek A. Bismar
Publikováno v:
The American Journal of Pathology. 184:871-877
Although various lines of evidence suggest that oxidative stress plays a role in human prostate cancer initiation and progression, there is a paucity of direct evidence for its role in tumor initiation. To begin to address this issue, we developed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e62a5c0a86fba0e49d9fdda6bc56c9
https://doi.org/10.1016/j.ajpath.2013.11.025
https://doi.org/10.1016/j.ajpath.2013.11.025
Publikováno v:
genesis. 46:229-234
Employing the Hprt locus as the site for targeted transgenesis we have developed mice expressing the tamoxifen-inducible Cre-ER(T2) fusion protein under the control of the ARR2-rat probasin promoter. This system enables external control over the timi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dbd0696473872af0f84e38d06beb0b5
https://doi.org/10.1002/dvg.20386
https://doi.org/10.1002/dvg.20386
Publikováno v:
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. 27(6)
Selenium (Se), which is a central component for the biosynthesis and functionality of selenoproteins, plays an important role in the anti-oxidative response, reproduction, thyroid hormone metabolism and the protection from infection and inflammation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a22a0c36078625f26f9ba90013a3418
https://pubmed.ncbi.nlm.nih.gov/25012761
https://pubmed.ncbi.nlm.nih.gov/25012761
Autor:
Gabriella Leung, Keith A. Sharkey, Frank R. Jirik, Derek M. McKay, Arthur Wang, Jason J. McDougall, Rabea Graepel, Michelle L. Villemaire
Publikováno v:
International journal for parasitology. 43(7)
Infection with helminth parasites triggers strong and stereotypic immune responses in humans and mice, which can protect against specific experimentally-induced autoimmune diseases. We have shown that infection with the rat tapeworm, Hymenolepis dimi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27366f0474a52070249ade7e7c133036
https://pubmed.ncbi.nlm.nih.gov/23583716
https://pubmed.ncbi.nlm.nih.gov/23583716
Autor:
Hallgrimur Benediktsson, Alan C. Peterson, Michelle L. Villemaire, H. Artee Luchman, Frank R. Jirik
Publikováno v:
PLoS ONE, Vol 3, Iss 12, p e3940 (2008)
PLoS ONE
PLoS ONE
Loss of the PTEN tumor suppressor is a common occurrence in human prostate cancer, particularly in advanced disease. In keeping with its role as a pivotal upstream regulator of the phosphatidylinositol 3-kinase signaling pathway, experimentally-induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21349e5db423897a591e46ae96c90b2
http://europepmc.org/articles/PMC2597775?pdf=render
http://europepmc.org/articles/PMC2597775?pdf=render
Autor:
Arvind K. Singla, Frank R. Jirik, Charlene M. Downey, Michelle L. Villemaire, Helen R. Buie, Steven K. Boyd
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41685 (2012)
PLoS ONE
PLoS ONE
Techniques for visualizing and quantifying the microvasculature of tumors are essential not only for studying angiogenic processes but also for monitoring the effects of anti-angiogenic treatments. Given the relatively limited information that can be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e3f2b2afc517e119a50f4492ec286c
https://doi.org/10.1371/journal.pone.0041685
https://doi.org/10.1371/journal.pone.0041685
Autor:
Zenobia Ali, Michelle L. Villemaire, Lina Chen, Houman Khosravani, Jawed Hamid, Frank R. Jirik, Shahid Hameed, Christophe Altier, Shigeki Tsutsui, Gerald W. Zamponi, Yunfeng Zhang
Publikováno v:
The Journal of Cell Biology
It is well established that misfolded forms of cellular prion protein (PrP [PrPC]) are crucial in the genesis and progression of transmissible spongiform encephalitis, whereas the function of native PrPC remains incompletely understood. To determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0912520f83eeea333ab6b7dac7c6b46
http://europepmc.org/articles/PMC2711610
http://europepmc.org/articles/PMC2711610