Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Michelle L Olsen"'
Autor:
Leanne M Holt, Raymundo D Hernandez, Natasha L Pacheco, Beatriz Torres Ceja, Muhannah Hossain, Michelle L Olsen
Publikováno v:
eLife, Vol 8 (2019)
Brain-derived neurotrophic factor (BDNF) is a critical growth factor involved in the maturation of the CNS, including neuronal morphology and synapse refinement. Herein, we demonstrate astrocytes express high levels of BDNF’s receptor, TrkB (in the
Externí odkaz:
https://doaj.org/article/2a24588f87724081878bac87c2f23a0e
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 8 (2014)
Cortical dysplasia is associated with intractable epilepsy and developmental delay in young children. Recent work with the rat freeze-induced focal cortical dysplasia (FCD) model has demonstrated that hyperexcitability in the dysplastic cortex is due
Externí odkaz:
https://doaj.org/article/4c08c308676d43d2ab09609a2c6ef177
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Brain derived neurotrophic factor (BDNF) is the most studied trophic factor in the central nervous system (CNS), and its role in the maturation of neurons, including synapse development and maintenance has been investigated intensely for over three d
Externí odkaz:
https://doaj.org/article/9fd182a2e7d540a79816c19c66dae4ea
Autor:
John Leonard, Xiaoran Wei, Jack Browning, Erwin Kristobal Gudenschwager-Basso, Jiangtao Li, Elizabeth A. Harris, Michelle L. Olsen, Michelle H. Theus
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Post-traumatic epilepsy (PTE) stands as one of the numerous debilitating consequences that follow traumatic brain injury (TBI). Despite its impact on many individuals, the current landscape offers only a limited array of reliable treatment o
Externí odkaz:
https://doaj.org/article/9cb92b6879b543e8954ff19ab63f43ae
Autor:
Colin M. Cleary, Jack L. Browning, Moritz Armbruster, Cleyton R. Sobrinho, Monica L. Strain, Sarvin Jahanbani, Jaseph Soto-Perez, Virginia E. Hawkins, Chris G. Dulla, Michelle L. Olsen, Daniel K. Mulkey
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Astrocytes in the retrotrapezoid nucleus (RTN) stimulate breathing in response to CO2/H+, however, it is not clear how these cells detect changes in CO2/H+. Considering Kir4.1/5.1 channels are CO2/H+-sensitive and important for several astro
Externí odkaz:
https://doaj.org/article/1f960e43c3b940399d7ba13f775dde08
Autor:
Erwin K. Gudenschwager Basso, Jing Ju, Eman Soliman, Caroline de Jager, Xiaoran Wei, Kevin J. Pridham, Michelle L. Olsen, Michelle H. Theus
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Monocytes represent key cellular elements that contribute to the neurological sequela following brain injury. The current study reveals that trauma induces the augmented release of a transcriptionally distinct CD115+/Ly6Chi monocyte populati
Externí odkaz:
https://doaj.org/article/4a71437ef1c1430cb5de1c3e6795ff40
Autor:
Elizabeth A. Kowalski, Eman Soliman, Colin Kelly, Erwin Kristobal Gudenschwager Basso, John Leonard, Kevin J. Pridham, Jing Ju, Alison Cash, Amanda Hazy, Caroline de Jager, Alexandra M. Kaloss, Hanzhang Ding, Raymundo D. Hernandez, Gabe Coleman, Xia Wang, Michelle L. Olsen, Alicia M. Pickrell, Michelle H. Theus
Publikováno v:
JCI Insight, Vol 7, Iss 15 (2022)
Circulating monocytes have emerged as key regulators of the neuroinflammatory milieu in a number of neuropathological disorders. Ephrin type A receptor 4 (Epha4) receptor tyrosine kinase, a prominent axon guidance molecule, has recently been implicat
Externí odkaz:
https://doaj.org/article/d48e080f6aa64183bed8ef43cb49ca19
Autor:
Erwin Kristobal Gudenschwager-Basso, Oleksii Shandra, Troy Volanth, Dipan C. Patel, Colin Kelly, Jack L. Browning, Xiaoran Wei, Elizabeth A. Harris, Dzenis Mahmutovic, Alexandra M. Kaloss, Fernanda Guilhaume Correa, Jeremy Decker, Biswajit Maharathi, Stefanie Robel, Harald Sontheimer, Pamela J. VandeVord, Michelle L. Olsen, Michelle H. Theus
Publikováno v:
Cells, Vol 12, Iss 9, p 1248 (2023)
Background: Traumatic brain injury (TBI) remains a significant risk factor for post-traumatic epilepsy (PTE). The pathophysiological mechanisms underlying the injury-induced epileptogenesis are under investigation. The dentate gyrus—a structure tha
Externí odkaz:
https://doaj.org/article/bebfb1ee64114a2ba984cef78cea5921
Autor:
Dipan C. Patel, Nathaniel Swift, Bhanu P. Tewari, Jack L. Browning, Courtney Prim, Lata Chaunsali, Ian Kimbrough, Michelle L. Olsen, Harald Sontheimer
Publikováno v:
bioRxiv
Alterations in the extracellular matrix (ECM) are common in epilepsy, yet whether they are cause or consequence of disease is unknow. Using Theiler’s virus infection model of acquired epilepsy we findde novoexpression of chondroitin sulfate proteog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f33041a146abc6d076e8d4873df4dcbe
https://europepmc.org/articles/PMC10245664/
https://europepmc.org/articles/PMC10245664/
Publikováno v:
Current Neuropharmacology. 20:5-15
General anesthetics are a mainstay of modern medicine, and although much progress has been made towards identifying molecular targets of anesthetics and neural networks contributing to endpoints of general anesthesia, our understanding of how anesthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::897f1e55cc20efb2f045389c9c6959bb
https://doi.org/10.2174/1570159x19666210215120755
https://doi.org/10.2174/1570159x19666210215120755