Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Michelle L Delco"'
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0297947 (2024)
In various biological systems, analyzing how cell behaviors are coordinated over time would enable a deeper understanding of tissue-scale response to physiologic or superphysiologic stimuli. Such data is necessary for establishing both normal tissue
Externí odkaz:
https://doaj.org/article/cd83df011d414db2ae147d1705cdd700
Autor:
Jingyang Zheng, Thomas Wyse Jackson, Lisa A Fortier, Lawrence J Bonassar, Michelle L Delco, Itai Cohen
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0278626 (2022)
Cellular response to stimulation governs tissue scale processes ranging from growth and development to maintaining tissue health and initiating disease. To determine how cells coordinate their response to such stimuli, it is necessary to simultaneous
Externí odkaz:
https://doaj.org/article/6beeca76724244f8953af7c7755458b0
Autor:
Megan J. Fahey, Maureen P. Bennett, Matthew Thomas, Irene Vivancos-Koopman, Lindsay Browning, Lawrence J. Bonassar, Michelle L. Delco
Avascular soft tissues of the skeletal system, including articular cartilage, have limited healing capacity, in part due to their low metabolic activity. No drugs are available that can prevent or slow the development of osteoarthritis (OA) after joi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::675214dcde73415de79f8649901a8d77
https://doi.org/10.1101/2022.05.12.491696
https://doi.org/10.1101/2022.05.12.491696
Autor:
Lisa A. Fortier, Marta Cercone, Laura E. Keller, Michelle L. Delco, Liliya Becktell, Kristina V. Wells
Publikováno v:
The American journal of sports medicine. 50(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97a9947510a43cca225c8ddba57769a0
https://pubmed.ncbi.nlm.nih.gov/35289225
https://pubmed.ncbi.nlm.nih.gov/35289225
Autor:
Matthew A. Thomas, Megan J. Fahey, Brenna R. Pugliese, Rebecca M. Irwin, Marc A. Antonyak, Michelle L. Delco
Publikováno v:
Frontiers in bioengineering and biotechnology. 10
Cartilage and other skeletal soft tissues heal poorly after injury, in part due to their lack of vascularity and low metabolic rate. No pharmacologic approaches have proven effective in preventing chronic degenerative disease after joint injury. Mese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::775d613fb7737259a03ae6dfcd9af34f
https://pubmed.ncbi.nlm.nih.gov/36082164
https://pubmed.ncbi.nlm.nih.gov/36082164
Autor:
Nikita Srivastava, Michelle L. Delco
Publikováno v:
Early Osteoarthritis ISBN: 9783030794842
Early Osteoarthritis
Early Osteoarthritis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6dd1eff934db6fb18234ef95e970ef0
https://doi.org/10.1007/978-3-030-79485-9_13
https://doi.org/10.1007/978-3-030-79485-9_13
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Osteoarthritis is a global health problem that affects load-bearing joints, causing loss of mobility and enormous healthcare costs. However, disease-modifying approaches are lacking. Here, we report a cellular mechanism of inflammatory s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::371c03608b6f992ff68f77c3963a45ae
https://pubmed.ncbi.nlm.nih.gov/33758095
https://pubmed.ncbi.nlm.nih.gov/33758095
Publikováno v:
Journal of the American Veterinary Medical Association. 255(11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17944fd9b16e944841af884e10f5aa55
https://pubmed.ncbi.nlm.nih.gov/31730432
https://pubmed.ncbi.nlm.nih.gov/31730432
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
No disease-modifying osteoarthritis (OA) drugs are available to prevent posttraumatic osteoarthritis (PTOA). Mitochondria (MT) mediate the pathogenesis of many degenerative diseases, and recent evidence indicates that MT dysfunction is a peracute (wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8407e99a8b68ca60a1b5d0289b068f63
https://pubmed.ncbi.nlm.nih.gov/29469223
https://pubmed.ncbi.nlm.nih.gov/29469223
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 36(2)
Mitochondrial (MT) dysfunction is known to occur in chondrocytes isolated from end-stage osteoarthritis (OA) patients, but the role of MT dysfunction in the initiation and early pathogenesis of post-traumatic OA (PTOA) remains unclear. The objective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b70d2bccb667f942615a510ce1f76a67
https://pubmed.ncbi.nlm.nih.gov/28696002
https://pubmed.ncbi.nlm.nih.gov/28696002