Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Michelle L, Villasmil"'
Autor:
Michelle L Villasmil, Antonio Daniel Barbosa, Jessie Lee Cunningham, Symeon Siniossoglou, Joseph T Nickels
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0235746 (2020)
Azole resistant fungal infections remain a health problem for the immune compromised. Current therapies are limited due to rises in new resistance mechanisms. Therefore, it is important to identify new drug targets for drug discovery and novel therap
Externí odkaz:
https://doaj.org/article/69957f3095894e4e9a1f75421cbf0efb
Autor:
Frank L. Conlon, Kimberly Sauls, Meng Zou, Li Wang, Todd M. Greco, Michelle L. Villasmil, Li Qian, Ileana M. Cristea
Publikováno v:
Cell Reports, Vol 22, Iss 7, Pp 1913-1922 (2018)
Direct reprogramming of fibroblasts into cardiomyocyte-like cells (iCM) holds great potential for heart regeneration and disease modeling and may lead to future therapeutic applications. Currently, application of this technology is limited by our lac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98370b36872728b6280e17429b2fbf77
http://www.sciencedirect.com/science/article/pii/S2211124718300792
http://www.sciencedirect.com/science/article/pii/S2211124718300792
Autor:
Joseph T. Nickels, Antonio Daniel Barbosa, Symeon Siniossoglou, Michelle L. Villasmil, Jessie Lee Cunningham
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 7, p e0235746 (2020)
PLoS ONE, Vol 15, Iss 7, p e0235746 (2020)
Azole resistant fungal infections remain a health problem for the immune compromised. Current therapies are limited due to rises in new resistance mechanisms. Therefore, it is important to identify new drug targets for drug discovery and novel therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f02142288cb64a49105676afb7244603
https://doi.org/10.1371/journal.pone.0235746
https://doi.org/10.1371/journal.pone.0235746
Autor:
Jamie Francisco, Christina Gallo-Ebert, Joseph T. Nickels, Michelle L. Villasmil, Hsing-Yin Liu
Ceramides and sphingolipid intermediates are well-established regulators of the cell cycle. In the budding yeast Saccharomyces cerevisae, the complex sphingolipid backbone, ceramide, comprises a long chain sphingoid base, a polar head group, and a ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b79447cb72aa1e7134ee72b35e27d9
https://europepmc.org/articles/PMC5736334/
https://europepmc.org/articles/PMC5736334/
Autor:
Melissa Donigan, Christina Gallo-Ebert, Joseph T. Nickels, Michelle L. Villasmil, Jamie Francisco, Melody Brower, Hsing-Yin Liu
Sphingolipids are major constituents of membranes. A number of S. cerevisiae sphingolipid intermediates such as long chains sphingoid bases (LCBs) and ceramides act as signaling molecules regulating cell cycle progression, adaptability to heat stress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7edc6735ff64422c7d13f1781fb9bfde
https://europepmc.org/articles/PMC4943704/
https://europepmc.org/articles/PMC4943704/
Autor:
Desiree R Romano, Melissa Donigan, Weiwei Chen, Christina Gallo-Ebert, Sean G. Chadwick, Michelle L. Villasmil, Joseph T. Nickels, Devanshi Pandya, Paula McCourt, Scott E. Gygax, Judith Franco
Publikováno v:
Fungal Genetics and Biology. 49:101-113
The lipid transporter Arv1 regulates sterol trafficking, and glycosylphosphatidylinositol and sphingolipid biosyntheses in Saccharomyces cerevisiae. ScArv1 contains an Arv1 homology domain (AHD) that is conserved at the amino acid level in the pathog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ebab4c2f3aec88e035d42f052513e7
https://doi.org/10.1016/j.fgb.2011.11.006
https://doi.org/10.1016/j.fgb.2011.11.006
Publikováno v:
FEMS Yeast Research. 11:524-527
In Saccharomyces cerevisiae, ARV1 encodes a 321 amino acid transmembrane protein localized to the endoplasmic reticulum (ER) and Golgi. It has been shown previously that arv1 cells harbor defects in sphingolipid and glycosylphosphatidylinositol biosy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ebc5f1da115333c4995fd6f530ff4ad
https://doi.org/10.1111/j.1567-1364.2011.00737.x
https://doi.org/10.1111/j.1567-1364.2011.00737.x
Publikováno v:
Biochemical Society transactions. 40(2)
The Kes1 OSBP (oxysterol-binding protein) is a key regulator of membrane trafficking through the TGN (trans-Golgi network) and endosomal membranes. We demonstrated recently that Kes1 acts as a sterol-regulated rheostat for TGN/endosomal phosphatidyli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6590fbfa50135c812febe0a3675655ce
https://pubmed.ncbi.nlm.nih.gov/22435832
https://pubmed.ncbi.nlm.nih.gov/22435832
Publikováno v:
FEMS yeast research. 11(6)
In Saccharomyces cerevisiae, ARV1 encodes a 321 amino acid transmembrane protein localized to the endoplasmic reticulum (ER) and Golgi. It has been shown previously that arv1 cells harbor defects in sphingolipid and glycosylphosphatidylinositol biosy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::836d565db99c8030de33ead867449472
https://pubmed.ncbi.nlm.nih.gov/21539707
https://pubmed.ncbi.nlm.nih.gov/21539707
Publikováno v:
Cytometry. Part A : the journal of the International Society for Analytical Cytology. 71(6)
Background: Immunophenotyping of blood leukocytes often involves fixation with paraformaldehyde prior to cytometry analysis. However, the influence of cell type and marker specificity on the stability of fluorescence intensity after fixation has not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5813023402c39351394447536c574b
https://pubmed.ncbi.nlm.nih.gov/17326232
https://pubmed.ncbi.nlm.nih.gov/17326232