Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Michelle K. Skime"'
Autor:
Siamak MahmoudianDehkordi, Ahmed T. Ahmed, Sudeepa Bhattacharyya, Xianlin Han, Rebecca A. Baillie, Matthias Arnold, Michelle K. Skime, Lisa St. John-Williams, M. Arthur Moseley, J. Will Thompson, Gregory Louie, Patricio Riva-Posse, W. Edward Craighead, William McDonald, Ranga Krishnan, A. John Rush, Mark A. Frye, Boadie W. Dunlop, Richard M. Weinshilboum, Rima Kaddurah-Daouk, The Mood Disorders Precision Medicine Consortium (MDPMC)
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Selective serotonin reuptake inhibitors (SSRIs) are the first-line treatment for major depressive disorder (MDD), yet their mechanisms of action are not fully understood and their therapeutic benefit varies among individuals. We used a targe
Externí odkaz:
https://doaj.org/article/9ab1fb8fadf043bab4c692f343ee6618
Autor:
Azmeraw T. Amare, Klaus Oliver Schubert, Fasil Tekola-Ayele, Yi-Hsiang Hsu, Katrin Sangkuhl, Gregory Jenkins, Ryan M. Whaley, Poulami Barman, Anthony Batzler, Russ B. Altman, Volker Arolt, Jürgen Brockmöller, Chia-Hui Chen, Katharina Domschke, Daniel K. Hall-Flavin, Chen-Jee Hong, Ari Illi, Yuan Ji, Olli Kampman, Toshihiko Kinoshita, Esa Leinonen, Ying-Jay Liou, Taisei Mushiroda, Shinpei Nonen, Michelle K. Skime, Liewei Wang, Masaki Kato, Yu-Li Liu, Verayuth Praphanphoj, Julia C. Stingl, William V. Bobo, Shih-Jen Tsai, Michiaki Kubo, Teri E. Klein, Richard M. Weinshilboum, Joanna M. Biernacka, Bernhard T. Baune
Publikováno v:
Frontiers in Psychiatry, Vol 9 (2018)
Studies reported a strong genetic correlation between the Big Five personality traits and major depressive disorder (MDD). Moreover, personality traits are thought to be associated with response to antidepressants treatment that might partly be media
Externí odkaz:
https://doaj.org/article/a8e18a3d523942889fbbed11197e76e3
Autor:
Michelle K Skime, Ajeng J Puspitasari, Melanie T Gentry, Dagoberto Heredia Jr, Craig N Sawchuk, Wendy R Moore, Monica J Taylor-Desir, Kathryn M Schak
Publikováno v:
JMIR Mental Health, Vol 9, Iss 1, p e30204 (2022)
BackgroundAlthough group-based intensive outpatient programs (IOPs) are a level of care commonly utilized by adults with serious mental illness, few studies have examined the acceptability of group-based IOPs that required rapid transition to a telem
Externí odkaz:
https://doaj.org/article/21e1c98feb4946e993eb89f0056fa7eb
Autor:
Ming‐Fen Ho, Cheng Zhang, Lixuan Wei, Lingxin Zhang, Irene Moon, Jennifer R. Geske, Michelle K. Skime, Doo‐Sup Choi, Joanna M. Biernacka, Tyler S. Oesterle, Mark A. Frye, Marvin D. Seppala, Victor M. Karpyak, Hu Li, Richard M. Weinshilboum
Publikováno v:
British Journal of Pharmacology. 179:3330-3345
Acamprosate is an anti-craving drug used for the pharmacotherapy of alcohol use disorder (AUD). However, only some patients achieve optimal therapeutic outcomes. This study was designed to explore differences in metabolomic profiles between patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dbd093a9eeaeca0ebf9c5832d96482e
https://doi.org/10.1111/bph.15795
https://doi.org/10.1111/bph.15795
Autor:
Fred H. Gage, Caroline Becronis, Amy T. Le, Krishna C. Vadodaria, Michelle K. Skime, Timothy J. Nelson, Kelly J. Heard, Callie Fredlender, Richard M. Weinshilboum, Yuan Ji, Maxim N. Shokhirev, Daniel K. Hall-Flavin, Nadia Zahid
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Translational Psychiatry
Translational Psychiatry
Major depressive disorder (MDD) is a prevalent psychiatric disorder, and exposure to stress is a robust risk factor for MDD. Clinical data and rodent models have indicated the negative impact of chronic exposure to stress-induced hormones like cortis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c769583229bbd3aedebff75b559e8ed3
https://doaj.org/article/753b9b999f8c450c8e0472172f86f547
https://doaj.org/article/753b9b999f8c450c8e0472172f86f547
Autor:
Richard M. Weinshilboum, David Goldman, Jennifer R. Geske, Victor M. Karpyak, Sofia Pozsonyiova, Colin A. Hodgkinson, Lea Zillich, Ada Man-Choi Ho, Ray Anton, Colin L. Colby, Ming Fen Ho, Brandon J. Coombes, Anthony Batzler, Stephanie S. O'Malley, Josef Frank, Joanna M. Biernacka, M. Rietschel, Karl Mann, Falk Kiefer, Michelle K. Skime
Publikováno v:
Neuropsychopharmacology
Naltrexone can aid in reducing alcohol consumption, while acamprosate supports abstinence; however, not all patients with alcohol use disorder (AUD) benefit from these treatments. Here we present the first genome-wide association study of AUD treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234df74c324ab363a2b228db4e2221a5
https://doi.org/10.1038/s41386-021-01097-0
https://doi.org/10.1038/s41386-021-01097-0
Autor:
Ravishankar K. Iyer, Tanja Brückl, Joanna M. Biernacka, Madhukar H. Trivedi, Rickey E. Carter, Mark A. Frye, Michelle K. Skime, Richard M. Weinshilboum, Taryn L. Mayes, A. John Rush, Elisabeth B. Binder, Drew Neavin, Paul E. Croarkin, Arjun P. Athreya, William V. Bobo, Liewei Wang, Ditlev Monrad
Publikováno v:
Neuropsychopharmacology
Heterogeneity in the clinical presentation of major depressive disorder and response to antidepressants limits clinicians’ ability to accurately predict a specific patient’s eventual response to therapy. Validated depressive symptom profiles may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5e6b3ef3cf0c5915f7299d052c5826d
http://europepmc.org/articles/PMC8134509
http://europepmc.org/articles/PMC8134509
Autor:
Victor M. Karpyak, Brandon J. Coombes, Jennifer R. Geske, Vanessa M. Pazdernik, Terry Schneekloth, Bhanu Prakash Kolla, Tyler Oesterle, Larissa L. Loukianova, Michelle K. Skime, Ada Man-Choi Ho, Quyen Ngo, Cedric Skillon, Ming-Fen Ho, Richard Weinshilboum, Joanna M. Biernacka
Publikováno v:
Drug and Alcohol Dependence. 243:109753
Lifetime history of major depressive disorder (MDD) has a sex-specific association with pretreatment alcohol consumption in patients with alcohol dependence. Here, we investigated the association of genetic load for MDD estimated using a polygenic ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cda3001f710730326434007e10d93c6d
https://doi.org/10.1016/j.drugalcdep.2022.109753
https://doi.org/10.1016/j.drugalcdep.2022.109753
Autor:
Paul E. Croarkin, Jeremiah B. Joyce, Joanna M. Biernacka, Madhukar H. Trivedi, Duan Liu, Mark A. Frye, Liewei Wang, Caroline Grant, William V. Bobo, Arjun P. Athreya, Richard M. Weinshilboum, Michelle K. Skime, Siamak MahmoudianDehkordi, Rima Kaddurah-Daouk, Taryn L. Mayes, Thomas J. Carmody
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)
Translational Psychiatry
Translational Psychiatry
Combination antidepressant pharmacotherapies are frequently used to treat major depressive disorder (MDD). However, there is no evidence that machine learning approaches combining multi-omics measures (e.g., genomics and plasma metabolomics) can achi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f02fe4de584a549b4fae90ea4f5a644f
https://doi.org/10.1038/s41398-021-01632-z
https://doi.org/10.1038/s41398-021-01632-z
Autor:
Mazen Atiq, Cheng Zhang, Irene Moon, Brandon Coombes, Joanna M. Biernacka, Michelle K. Skime, Doo-Sup Choi, Mark A. Frye, Tyler Oesterle, Victor Karpyak, Kristen Schmidt, Kate Gliske, Quyen Ngo, Cedric Skillon, Marvin Seppala, Hu Li, Ming-Fen Ho, Richard Weinshilboum
Publikováno v:
Biological Psychiatry. 91:S109-S110
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01390f5f9f9e2b2148cd13351947db27
https://doi.org/10.1016/j.biopsych.2022.02.289
https://doi.org/10.1016/j.biopsych.2022.02.289