Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Michelle K. Mattson"'
Autor:
Michael Frost, Eduard Serra, David Viskochil, Bruce R. Korf, Michelle K. Mattson-Hoss, Glenn E. Croston, Herb Sarnoff
Publikováno v:
Journal of Translational Genetics and Genomics. 6:403-28
Neurofibromatosis type 1 (NF1) is a genetic disorder with a wide range of manifestations and severity. Currently, the few available NF1 treatments target specific manifestations, with no available therapies targeted to correct the underlying driver o
Publikováno v:
Frontiers in Materials, Vol 3 (2016)
The presence of membrane tubules in living cells is essential to many biological processes. In cells, one mechanism to form nano-sized lipid tubules is via molecular motor induced bilayer extraction. In this paper, we describe a simple experimental m
Externí odkaz:
https://doaj.org/article/a5322598e0cf48f8b638f0a975be4cc5
Autor:
Michelle K. Mattson, Steven P. Gross, Omid Vadpey, Caitlin L. Wynne, Babu J.N. Reddy, Richard B. Vallee, Dail Chapman, Abdo Durra
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Reddy, BJN; Mattson, M; Wynne, CL; Vadpey, O; Durra, A; Chapman, D; et al.(2016). Load-induced enhancement of Dynein force production by LIS1-NudE in vivo and in vitro. NATURE COMMUNICATIONS, 7, 12259. doi: 10.1038/ncomms12259. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/1vd4h15d
Nature Communications
Reddy, BJN; Mattson, M; Wynne, CL; Vadpey, O; Durra, A; Chapman, D; et al.(2016). Load-induced enhancement of Dynein force production by LIS1-NudE in vivo and in vitro. NATURE COMMUNICATIONS, 7, 12259. doi: 10.1038/ncomms12259. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/1vd4h15d
Nature Communications
Most sub-cellular cargos are transported along microtubules by kinesin and dynein molecular motors, but how transport is regulated is not well understood. It is unknown whether local control is possible, for example, by changes in specific cargo-asso
Calibration of Optical Tweezers for In Vivo Force Measurements: How do Different Approaches Compare?
Autor:
Michelle K. Mattson-Hoss, Yonggun Jun, Babu Reddy Janakaloti Narayanareddy, Suvranta K. Tripathy, Steven P. Gross
Publikováno v:
Biophysical Journal. 107(6):1474-1484
There is significant interest in quantifying force production inside cells, but since conditions in vivo are less well controlled than those in vitro, in vivo measurements are challenging. In particular, the in vivo environment may vary locally as fa
Autor:
Michelle K. Mattson-Hoss, Yamato Niitani, Elizabeth A. Gordon, Lee Bardwell, Steven P. Gross, Yonggun Jun, Michio Tomishige
Publikováno v:
Mattson-Hoss, MK; Niitani, Y; Gordon, EA; Jun, Y; Bardwell, L; Tomishige, M; et al.(2014). CK2 activates kinesin via induction of a conformational change. Proceedings of the National Academy of Sciences of the United States of America, 111(19), 7000-7005. doi: 10.1073/pnas.1321419111. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/9kv8246z
Kinesin is the canonical plus-end microtubule motor and has been the focus of intense study since its discovery in 1985. We previously demonstrated a time-dependent inactivation of kinesin in vitro that was fully reversible by the addition of purifie
Publikováno v:
Scientific Reports
Within living cells, the transport of cargo is accomplished by groups of molecular motors. Such collective transport could utilize mechanisms which emerge from inter-motor interactions in ways that are yet to be fully understood. Here we combined exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a883f9e5806fddf1bc4d93c89c4bc4c
http://arxiv.org/abs/1610.00184
http://arxiv.org/abs/1610.00184
Publikováno v:
Frontiers in Materials, Vol 3 (2016)
Lor, C; Lopes, JD; Mattson-Hoss, MK; Xu, J; & Hirst, LS. (2016). A Simple Experimental Model to Investigate Force Range for Membrane Nanotube Formation. FRONTIERS IN MATERIALS, 3. doi: 10.3389/fmats.2016.00006. UC Merced: Retrieved from: http://www.escholarship.org/uc/item/9zh9910z
Lor, C; Lopes, JD; Mattson-Hoss, MK; Xu, J; & Hirst, LS. (2016). A Simple Experimental Model to Investigate Force Range for Membrane Nanotube Formation. FRONTIERS IN MATERIALS, 3. doi: 10.3389/fmats.2016.00006. UC Merced: Retrieved from: http://www.escholarship.org/uc/item/9zh9910z
The presence of membrane tubules in living cells is essential to many biological processes. In cells, one mechanism to form nano-sized lipid tubules is via molecular motor induced bilayer extraction. In this paper, we describe a simple experimental m
Autor:
Changbong Hyeon, Michael Vershinin, Marvin E. Tanenbaum, Suvranta K. Tripathy, Jing Xu, Babu J.N. Reddy, Michelle K. Mattson-Hoss, Tory Doolin, Karim Arabi, Steven P. Gross, Dail Chapman
Publikováno v:
Traffic, 18(10), 658. Blackwell Munksgaard
Traffic, 18(10), 658-671. Blackwell Munksgaard
Traffic, 18(10), 658-671. Blackwell Munksgaard
The kinesin family proteins are often studied as prototypical molecular motors; a deeper understanding of them can illuminate regulation of intracellular transport. It is typically assumed that they function identically. Here we find that this assump
Autor:
Steven P. Gross, Richard J. McKenney, Jing Xu, Suvranta K. Tripathy, Michelle K. Mattson, Roby Sigua, Preetha Anand, Alex Mogilner, Ambarish Kunwar, Michael Vershinin, Clare C. Yu
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 108(47)
Intracellular transport via the microtubule motors kinesin and dynein plays an important role in maintaining cell structure and function. Often, multiple kinesin or dynein motors move the same cargo. Their collective function depends critically on th
Autor:
Preetha Anand, Clare C. Yu, Michael Vershinin, Jing Xu, Suvranta K. Tripathy, Richard J. McKenney, Roby Sigua, Steven P. Gross, Michelle K. Mattson
Publikováno v:
Biophysical Journal. (3):370a
Intra-cellular transport via the microtubule motors kinesin and dynein plays an important role in maintaining cell structure and function. Often, multiple kinesin or dynein motors move the same cargo. Their collective function depends critically on t