Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Michelle K. Mater"'
Autor:
David A. Pan, Michelle K. Mater, Annette P. Thelen, Jeffrey M. Peters, Frank J. Gonzalez, Donald B. Jump
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 5, Pp 742-751 (2000)
The glycolytic enzyme, L-pyruvate kinase (L-PK), plays an important role in hepatic glucose metabolism. Insulin and glucose induce L-PK gene expression, while glucagon and polyunsaturated fatty acids (PUFA) inhibit L-PK gene expression. We have been
Externí odkaz:
https://doaj.org/article/1a16505d17984b7b8035535958359176
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 6, Pp 1045-1052 (1999)
N–6 polyunsaturated fatty acids (PUFA) suppress hepatic and adipocyte de novo lipogenesis by inhibiting the transcription of genes encoding key lipogenic proteins. In cultured 3T3-L1 adipocytes, arachidonic acid (20:4,n–6) suppression of lipogeni
Externí odkaz:
https://doaj.org/article/cb4d83722c1640f38751972a18033542
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 7, Pp 1327-1334 (1998)
This report examines the effect of polyunsaturated fatty acids (PUFA) on lipogenic gene expression in cultured 3T3-L1 adipocytes. Arachidonic acid (20:4, n–6) and eicosapentaenoic acid (20:5, n–3) suppressed mRNAs encoding fatty acid synthase (FA
Externí odkaz:
https://doaj.org/article/6df53c5fa6f24e7a99f79d7c1738ab0e
Publikováno v:
Journal of Biological Chemistry. 276:34419-34427
Sterol regulatory element binding protein-1c (SREBP-1c) is a key hepatic transcription factor involved in lipogenic gene expression. In an effort to understand the role SREBP-1c plays in lipogenic gene transcription, we have examined the functional i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e05fd7db899723b92ed3fb8bcdba776
https://doi.org/10.1074/jbc.m105471200
https://doi.org/10.1074/jbc.m105471200
Autor:
Annette P. Thelen, Jeffrey M. Peters, David A. Pan, Donald B. Jump, Frank J. Gonzalez, Michelle K. Mater
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 5, Pp 742-751 (2000)
The glycolytic enzyme, L-pyruvate kinase (L-PK), plays an important role in hepatic glucose metabolism. Insulin and glucose induce L-PK gene expression, while glucagon and polyunsaturated fatty acids (PUFA) inhibit L-PK gene expression. We have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c730e5c5d9390dbf97117ed1d0845307
http://www.sciencedirect.com/science/article/pii/S002222752032383X
http://www.sciencedirect.com/science/article/pii/S002222752032383X
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 7, Pp 1327-1334 (1998)
This report examines the effect of polyunsaturated fatty acids (PUFA) on lipogenic gene expression in cultured 3T3-L1 adipocytes. Arachidonic acid (20:4, n–6) and eicosapentaenoic acid (20:5, n–3) suppressed mRNAs encoding fatty acid synthase (FA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87f1c344b80e76de182f9538b9a3b9bc
https://doi.org/10.1016/s0022-2275(20)32513-x
https://doi.org/10.1016/s0022-2275(20)32513-x
Publikováno v:
The Journal of biological chemistry. 274(46)
Polyunsaturated fatty acids (PUFA) suppress hepatic lipogenic gene transcription through a peroxisome proliferator activated receptor alpha (PPARalpha)- and cyclooxygenase-independent mechanism. Recently, the sterol response element-binding protein 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f04590589ea148e0bdfc861021f536a4
https://pubmed.ncbi.nlm.nih.gov/10551830
https://pubmed.ncbi.nlm.nih.gov/10551830
Publikováno v:
Lipids.
Dietary polyunsaturated fatty acids (PUFA) have profound effects on hepatic gene transcription leading to significant changes in lipid metabolism. PUFA rapidly suppress transcription of genes encoding specific lipogenic and glycolytic enzymes and ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b422a9df4c046b7270cc4c17f3e5dd06
https://pubmed.ncbi.nlm.nih.gov/10419152
https://pubmed.ncbi.nlm.nih.gov/10419152