Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Michelle K. Leach"'
Autor:
Michelle K. Leach, Frank Winterroth, Zhang-Qi Feng, Joseph M. Corey, Arjun Rastogi, Christina M. White, Eric W. Franz, Zhongze Gu
Publikováno v:
Journal of Biomedical Materials Research Part A. 104:966-974
One obstacle in neural repair is facilitating axon growth long enough to reach denervated targets. Recent studies show that axonal growth is accelerated by applying tension to bundles of neurites, and additional studies show that mechanical tension i
Publikováno v:
J. Mater. Chem. B. 1:339-346
Advanced scaffold materials are required for liver tissue engineering, to improve primary hepatocyte activity and hepatic function in vitro. The nanotopography of the scaffold material plays an important role in the regulation of cell growth and func
Autor:
Michelle K. Leach, Jinghang Wu, Zhongze Gu, Youssef I. Naim, Eric W. Franz, Joseph M. Corey, Zhang-Qi Feng, David C. Martin, Whirang Cho
Publikováno v:
Polymer. 54:702-708
This study reports a facile method for the fabrication of aligned Poly(3,4-ethylene dioxythiophene) (PEDOT) fibers and tubes based on electrospinning and oxidative chemical polymerization. Discrete PEDOT nano- and microfibers and nano- and microtubes
Publikováno v:
Materials Science and Engineering: C. 32:1779-1784
Electrospun polymer nanofibers show promise as components of scaffolds for tissue engineering because of their ability to orient regenerating cells. Our research focuses on aligned electrospun fiber scaffolds for nerve regeneration. Critical to this
Autor:
Lin Jin, Zhang-Qi Feng, Michelle K. Leach, Youssef I. Naim, Joseph M. Corey, Ting Wang, Mei Ling Zhu, Qing Jiang
Publikováno v:
Journal of Biomedical Nanotechnology. 8:1-9
Electrospinning is an exciting technique attracting more and more attention as a potential solution to the current challenges in the field of tissue engineering. This technique can be used to produce fibrous scaffolds with excellent biocompatibility
Autor:
Li Jiang, Long Zhang, Michelle K. Leach, Nongyue He, Wenjing Yang, Zhang-Qi Feng, Yan Hu, Ting Wang
Publikováno v:
International Journal of Pharmaceutics. 422:462-471
In this study, a single intraperitoneal injection of erythropoietin (EPO) loaded oligochitosan nanoparticles (epo-NPs) (average diameter 266 nm) was investigated as a treatment for periventricular leukomalacia (PVL). Nanoparticles were fabricated usi
Autor:
Joseph M. Corey, Eva L. Feldman, Michelle K. Leach, Caitlyn C. Gertz, Lisa K. Birrell, David C. Martin
Publikováno v:
Developmental Neurobiology. 70:589-603
Neuritogenesis, neuronal polarity formation, and maturation of axons and dendrites are strongly influenced by both biochemical and topographical extracellular components. The aim of this study was to elucidate the effects of polylactic acid electrosp
Autor:
Zhongze Gu, Michelle K. Leach, Yitao Ding, Zhang-Qi Feng, Xue-hui Chu, Yichun Wang, Gan Wang, Ning-Ping Huang
Publikováno v:
Biomaterials. 31:3604-3612
Primary hepatocytes cultured in three dimensional tissue constructs composed of multicellular aggregates maintain normal differentiated cellular function in vitro while cultured monolayers do not. Here, we report a technique to induce hepatocyte aggr
Autor:
Michelle K. Leach, Shoshana L. Woo, Paul S. Cederna, Jana D. Moon, Nicholas B. Langhals, Ian C. Sando, Melanie G. Urbanchek
Publikováno v:
Journal of reconstructive microsurgery. 32(3)
Background This study compared epimysial patch electrodes with intramuscular hook electrodes using monopolar and bipolar recording configurations. The purpose was to determine which strategy transduced muscle signals with better fidelity for control
Autor:
Zhang-Qi, Feng, Eric W, Franz, Michelle K, Leach, Frank, Winterroth, Christina M, White, Arjun, Rastogi, Zhong-Ze, Gu, Joseph M, Corey
Publikováno v:
Journal of biomedical materials research. Part A. 104(4)
One obstacle in neural repair is facilitating axon growth long enough to reach denervated targets. Recent studies show that axonal growth is accelerated by applying tension to bundles of neurites, and additional studies show that mechanical tension i