Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Michelle K. Deaton"'
Autor:
Florine E.M. Scholte, Marko Zivcec, John V. Dzimianski, Michelle K. Deaton, Jessica R. Spengler, Stephen R. Welch, Stuart T. Nichol, Scott D. Pegan, Christina F. Spiropoulou, Éric Bergeron
Publikováno v:
Cell Reports, Vol 20, Iss 10, Pp 2396-2407 (2017)
Antiviral responses are regulated by conjugation of ubiquitin (Ub) and interferon-stimulated gene 15 (ISG15) to proteins. Certain classes of viruses encode Ub- or ISG15-specific proteases belonging to the ovarian tumor (OTU) superfamily. Their activi
Externí odkaz:
https://doaj.org/article/2913f622b2624efda670531f1ee47f80
Publikováno v:
Virology. :247-253
Arterivirus genus member Porcine reproductive and respiratory syndrome virus (PRRSV) causes an economically devastating disease, recently exacerbated by the emergence of highly pathogenic strains (HP-PRRSV). Within the nonstructural protein 2 of PRRS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c3945d924848cbc177b2dcbb8216f63
Publikováno v:
Journal of Virology
Nairoviruses are responsible for numerous diseases that affect both humans and animal. Recent work has implicated the viral ovarian tumor domain (vOTU) as a possible nairovirus virulence factor due to its ability to edit ubiquitin (Ub) bound to cellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4da6a7e860a15ee1f83b3151fb099891
https://doi.org/10.1128/jvi.03252-12
https://doi.org/10.1128/jvi.03252-12
Autor:
Eric Bergeron, N. J. Mank, Scott D. Pegan, Courtney M. Daczkowski, Michelle K. Deaton, M. M. Parham, G. K. Whitney, John V. Dzimianski
Publikováno v:
Journal of Virology
The regulation of the interferon type I (IFN-I) response has been shown to rely on posttranslational modification by ubiquitin (Ub) and Ub-like interferon-stimulated gene product 15 (ISG15) to stabilize, or activate, a variety of IFN-I signaling and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f42ba64815ae63c362dbe6215266f2c
https://europepmc.org/articles/PMC5008091/
https://europepmc.org/articles/PMC5008091/
Autor:
Kingshuk Ghosh, Stephen P. Ray, Glenn C. Capodagli, Scott D. Pegan, Lucas Sawle, Lauren A. F. Calkins, David Patterson, Michelle K. Deaton
Publikováno v:
Biochemistry. 51:6701-6713
Adenylosuccinate lyase (ADSL) deficiency is a rare autosomal recessive disorder, which causes a defect in purine metabolism resulting in neurological and physiological symptoms. ADSL executes two nonsequential steps in the de novo synthesis of AMP: t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::977db4cf748188bccda82c1b29e2d571
https://doi.org/10.1021/bi300796y
https://doi.org/10.1021/bi300796y
Publikováno v:
Acta crystallographica. Section D, Biological crystallography. 67(Pt 12)
Tuberculosis (TB) is a major infectious disease that accounts for over 1.7 million deaths every year. Mycobacterium tuberculosis, the causative agent of tuberculosis, enters the human host by the inhalation of infectious aerosols. Additionally, one t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24dabc05771112c9dd7760a3f0b881f8
https://pubmed.ncbi.nlm.nih.gov/22120738
https://pubmed.ncbi.nlm.nih.gov/22120738