Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Michelle K Wilson"'
MicroRNA profiling of ovarian granulosa cell tumours reveals novel diagnostic and prognostic markers
Autor:
Wei-Tzu Cheng, Roseanne Rosario, Anita Muthukaruppan, Michelle K Wilson, Kathryn Payne, Peter C. Fong, Andrew N. Shelling, Cherie Blenkiron
Publikováno v:
Clinical Epigenetics, Vol 9, Iss 1, Pp 1-10 (2017)
Abstract Background The aim of this study was to explore the clinical utility of microRNAs (miRNAs) as improved markers of ovarian granulosa cell tumours (GCTs) for cancer diagnosis and prognosis prediction. Current histopathological and genetic mark
Externí odkaz:
https://doaj.org/article/c2aec7e0385e4f5ba350ebf5d714dd5d
Autor:
Bradley J. Monk, Christine Parkinson, Myong Cheol Lim, David M. O'Malley, Ana Oaknin, Michelle K. Wilson, Robert L. Coleman, Domenica Lorusso, Paul Bessette, Sharad Ghamande, Athina Christopoulou, Diane Provencher, Emily Prendergast, Fuat Demirkiran, Olga Mikheeva, Oladapo Yeku, Anita Chudecka-Glaz, Michael Schenker, Ramey D. Littell, Tamar Safra, Hung-Hsueh Chou, Mark A. Morgan, Vít Drochýtek, Joyce N. Barlin, Toon Van Gorp, Fred Ueland, Gabriel Lindahl, Charles Anderson, Dearbhaile C. Collins, Kathleen Moore, Frederik Marme, Shannon N. Westin, Iain A. McNeish, Danny Shih, Kevin K. Lin, Sandra Goble, Stephanie Hume, Keiichi Fujiwara, Rebecca S. Kristeleit
Publikováno v:
Scientia
PURPOSE ATHENA (ClinicalTrials.gov identifier: NCT03522246 ) was designed to evaluate rucaparib first-line maintenance treatment in a broad patient population, including those without BRCA1 or BRCA2 (BRCA) mutations or other evidence of homologous re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::312a6e609ec98f3f3c5b48462663544d
https://hdl.handle.net/11351/8726
https://hdl.handle.net/11351/8726
Autor:
Keiichi Fujiwara, Robert L. Coleman, Amit M. Oza, Lara Maloney, Frederik Marmé, Bradley J. Monk, Ramez N. Eskander, R Kristeleit, Tamar Safra, Kevin K. Lin, David M. O'Malley, Shannon N. Westin, Nikolay Grechko, Ana Oaknin, Domenica Lorusso, Michelle K. Wilson, Thomas J. Herzog, Danny Shih, Stephanie Hume, Sandra Goble, Iain A. McNeish
Publikováno v:
International Journal of Gynecological Cancer
BackgroundThe optimal treatment strategy for women with newly diagnosed ovarian cancer has yet to be determined. Poly(ADP-ribose) polymerase (PARP) inhibitors have demonstrated substantial improvement in progression-free survival as monotherapy maint
Autor:
Sangeet Ghai, Xuan Li, Neesha C. Dhani, Gita Bhat, Wendy Hunt, Luisa Bonilla, Michelle McMullen, Ainhoa Madariaga, David Gutierrez, Stephanie Lheureux, Lawrence Kasherman, Sunu Cyriac, Michelle K. Wilson, Lisa Wang, Valerie Bowering, Amit M. Oza
Publikováno v:
American journal of obstetrics and gynecology. 225(6)
Background Despite the growing integration of mandatory biopsies for correlative endpoints within oncology clinical trials, there are sparse data on patient-reported outcomes, perceptions, and preferences. Objective This study aimed to prospectively
Autor:
Bradley J. Monk, Christine Parkinson, Myong Cheol Lim, David M. O'Malley, Ana Oaknin, Michelle K. Wilson, Robert L. Coleman, Domenica Lorusso, Amit M. Oza, Sharad A. Ghamande, Athina Christopoulou, Emily Prendergast, Fuat Demirkiran, Ramey D. Littell, Anita M. Chudecka-Glaz, Mark Aloysuis Morgan, Sandra M. Goble, Stephanie Hume, Keiichi Fujiwara, Rebecca Kristeleit
Publikováno v:
Journal of Clinical Oncology. 40:LBA5500-LBA5500
LBA5500 Background: While PARP inhibitors have shown efficacy as first-line (1L) maintenance treatment for patients (pts) with ovarian cancer (OC), questions remain about the pt population that may benefit from their use. ATHENA (NCT03522246) was des
Autor:
Gita Bhat, Sunu Cyriac, Michelle McMullen, Ainhoa Madariaga, Neesha C. Dhani, Michelle K. Wilson, Sangeet Ghai, Lawrence Kasherman, Amit M. Oza, Wendy Hunt, Valerie Bowering, Stephanie Lheureux, David Gutierrez, Luisa Bonilla, Lisa Wang, Xuan Li
Publikováno v:
Gynecologic Oncology. 162:S261-S262
Objectives: The aim of this study was to assess the impact of research biopsies on quality of life of patients (pts) with gynecologic malignancies, and determine which factors are associated with the pts willingness to undergo future biopsies. Method
MicroRNA profiling of ovarian granulosa cell tumours reveals novel diagnostic and prognostic markers
Autor:
Kathryn Payne, Cherie Blenkiron, Roseanne Rosario, Michelle K. Wilson, Andrew N. Shelling, Anita Muthukaruppan, Wei-Tzu Cheng, Peter C.C. Fong
Publikováno v:
Clinical Epigenetics, Vol 9, Iss 1, Pp 1-10 (2017)
Clinical Epigenetics
Clinical Epigenetics
Background The aim of this study was to explore the clinical utility of microRNAs (miRNAs) as improved markers of ovarian granulosa cell tumours (GCTs) for cancer diagnosis and prognosis prediction. Current histopathological and genetic markers, such
Autor:
P. Wimberger, Monica Bacon, David K. Gaffney, A. du Bois, Aikou Okamoto, Florence Joly, Alexander Reuss, Mansoor Raza Mirza, Ignace Vergote, Gavin Stuart, Rongyu Zang, Dolores Gallardo-Rincón, Eric Pujade-Lauraine, Amit M. Oza, M. Friedlander, Johanna Mäenpää, Michelle K. Wilson, Daisuke Aoki, Richard J. Edmondson, Kazunori Ochiai, Annamaria Ferrero, Domenica Lorusso, Suk-Joon Chang
Publikováno v:
Annals of Oncology. 28:727-732
This manuscript reports the consensus statements regarding recurrent ovarian cancer (ROC), reached at the fifth Ovarian Cancer Consensus Conference (OCCC), which was held in Tokyo, Japan, in November 2015. Three important questions were identified: (
Autor:
Tracy Stockley, Maksym Misyura, Christine Elser, R Demsky, Jeanna McCuaig, Michelle K. Wilson, Suzanne Kamel-Reid, Victoria Mandilaras, Amit M. Oza, P. Bedard, Helen Chow, S. Randall Armel, Alexandra Volenik, Hal K. Berman, Cescon D, Raymond H. Kim, Lisa Wang, Neda Stjepanovic, Eitan Amir
Publikováno v:
Cancer Research. 77:P3-09
Background: Variants in homologous recombination (HR) genes other than BRCA1/2 may cause a BRCA-like phenotype triple negative breast cancer (TNBC), which includes the sensitivity to platinums and DNA repair inhibitors. Evaluation of HR proficiency m
Autor:
Marcus O. Butler, Tracy Stockley, Philippe L. Bedard, Suzanne Kamel-Reid, Neesha C. Dhani, Stephanie Lheureux, Tong Zhang, Anna Spreafico, Lillian L. Siu, Amit M. Oza, Helen Mackay, Celeste Yu, Stephen Welch, Blaise Clarke, Patricia Shaw, Michelle K. Wilson
Publikováno v:
Gynecologic Oncology. 144:250-255
Background Genomic alterations that activate the MAPK signaling pathway frequently occur in Type I Epithelial Ovarian Cancers (EOCs). We evaluated therapeutic response outcomes in patients with type I EOC treated with genotype-matched therapy on clin