Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Michelle J. Bound"'
Autor:
Linda E. Watson, Helen L. Checklin, Liza K. Phillips, Tongzhi Wu, Christopher K. Rayner, Michelle J. Bound, Jacqueline Grivell, Karen L. Jones, Michael Horowitz
Publikováno v:
Clinical Nutrition. 38:2827-2832
Background and aims: Whey protein and guar gum have both been reported to reduce postprandial glycemia in health and type 2 diabetes, associated with stimulation of glucagon-like peptide-1 (GLP-1) and/or slowing of gastric emptying. Our aim was to ev
Autor:
Malcolm J. Borg, Jacqueline Grivell, Christopher K. Rayner, Michael Horowitz, Zilin Sun, Karen L. Jones, Tongzhi Wu, Michelle J. Bound
Publikováno v:
Diabetes, Obesity and Metabolism. 21:640-647
Aims: The gastrointestinal tract, particularly the lower gut, may be key to the anti-diabeticaction of metformin. We evaluated whether administration of metformin into the distal, vs the proximal, small intestine would be more effective in lowering p
Autor:
Linda E. Watson, Kylie Lange, Liza K. Phillips, Silvia Frascerra, Michelle J. Bound, Tongzhi Wu, Ele Ferrannini, Andrea Natali, Karen L. Jones, Christopher K. Rayner, Domenico Tricò, Michael Horowitz, Jacqueline Grivell, Andrea Mari
Publikováno v:
Diabetes care. 44(1)
The authors wish to correct some minor errors in this article: 1. The fasting insulin secretion rate was correctly shown in Table 1 to be slightly increased after lixisenatide treatment, whereas the text of the Results and Conclusions sections incorr
Autor:
Ele Ferrannini, Andrea Mari, Linda E. Watson, Jacqueline Grivell, Kylie Lange, Tongzhi Wu, Michael Horowitz, Liza K. Phillips, Domenico Tricò, Michelle J. Bound, Silvia Frascerra, Andrea Natali, Christopher K. Rayner, Karen L. Jones
OBJECTIVE Tachyphylaxis for slowing of gastric emptying is seen with continuous exposure to glucagon-like peptide 1 (GLP-1). We therefore aimed to establish whether prolonged use of a “short-acting” GLP-1 receptor agonist, lixisenatide, achieves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::027ab2fee3dd5d94c32158947cc7e714
https://doi.org/10.2337/figshare.12245516
https://doi.org/10.2337/figshare.12245516
Autor:
Christopher K. Rayner, Carolyn F. Deacon, Jens J. Holst, Jens F. Rehfeld, Tongzhi Wu, Michelle J. Bound, Bolette Hartmann, Simon Veedfald, Michael Horowitz, Jacqueline Grivell
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 103:4409-4418
ContextThe mechanisms regulating the postprandial suppression of ghrelin secretion remain unclear, but recent observations in rats indicate that an increase in duodenal osmolarity is associated with a reduction in ghrelin levels. Several hormones hav
Autor:
Christopher K. Rayner, Michael Horowitz, Linda E. Watson, Liza K. Phillips, Karen L. Jones, Tongzhi Wu, Michelle J. Bound
Aims: To evaluate the natural history of gastric emptying in type 2 diabetes. Methods: 12 patients with type 2 diabetes (7 female; age 65.6 ± 1.2 years; duration of known diabetes 22.9 ± 1.5 years) were invited to return for repeat measurements of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c99790fdaeabd32ac78362cecde384c4
https://hdl.handle.net/11541.2/139868
https://hdl.handle.net/11541.2/139868
Autor:
Tanya J. Little, Laurence G. Trahair, Carolyn F. Deacon, Karen L. Jones, Michelle J. Bound, Michael Horowitz, Xiang Zhang, Christopher K. Rayner, Tongzhi Wu
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 101:4769-4778
Context: The rate of gastric emptying is an important determinant of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) secretion and may influence the magnitude of glucose lowering by dipeptidyl peptidase-4 (DPP-4
Autor:
Xiang Zhang, Richard L. Young, Christopher K. Rayner, Karen L. Jones, Michael Horowitz, Michelle J. Bound, Tongzhi Wu, Sanyuan Hu
Publikováno v:
Diabetes care. 42(4)
OBJECTIVE Cells releasing glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) are distributed predominately in the proximal and distal gut, respectively. Hence, the region of gut exposed to nutrients may influence G
Autor:
Liza K. Phillips, Karen L. Jones, Linda E. Watson, Jacqueline Grivell, Helen L. Checklin, Michelle J. Bound, Michael Horowitz, Peter M. Clifton, Christopher K. Rayner, Tongzhi Wu
Publikováno v:
Diabetes, obesitymetabolismREFERENCES. 21(4)
Aims: To evaluate the effects of 12 weeks of treatment with a whey/guar preload on gastric emptying, postprandial glycaemia and glycated haemoglobin (HbA1c) levels in people with type 2 diabetes (T2DM). Materials and methods: A total of 79 people wit
Autor:
Joan Khoo, Michael Horowitz, Chinmay S. Marathe, Tongzhi Wu, Jessica Chang, Benjamin Crouch, Rachael S. Rigda, Christopher K. Rayner, Sony S. Thazhath, Michelle J. Bound, Karen L. Jones, Helen L. Checklin, Paul Kuo
Publikováno v:
Diabetes. 65:269-275
The short-acting glucagon-like peptide 1 receptor agonist exenatide reduces postprandial glycemia, partly by slowing gastric emptying, although its impact on small intestinal function is unknown. In this study, 10 healthy subjects and 10 patients wit