Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Michelle J Meyer"'
Autor:
Tracy L Adair-Kirk, Gail L Griffin, Michelle J Meyer, Diane G Kelley, Jeffrey H Miner, Douglas R Keene, M Peter Marinkovich, J Michael Ruppert, Jouni Uitto, Robert M Senior
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45546 (2012)
Laminin-332 is a heterotrimeric basement membrane component comprised of the α3, ß3, and γ2 laminin chains. Laminin-332 modulates epithelial cell processes, such as adhesion, migration, and differentiation and is prominent in many embryonic and ad
Externí odkaz:
https://doaj.org/article/0d0b7f25a524459b96d7840d807b0f76
Autor:
Xingjie Ping, Michelle J. Meyer, Nicolas M. Zahn, Lalit K. Golani, Dishary Sharmin, Kamal P. Pandey, Sepideh Revanian, Prithu Mondal, Xiaoming Jin, Leggy A. Arnold, Rok Cerne, James M. Cook, Branka Divović, Miroslav M. Savić, Arnold Lippa, Jodi L. Smith, Jeffrey M. Witkin
Publikováno v:
Drug Development Research
A series of imidazodiazepines has been developed that possess reduced sedative liabilities but retain efficacy in anticonvulsant screening models. The latest of these compounds, (5-(8-ethynyl-6-(pyridin-2-yl)-4H-benzo[f]imidazole[1,5-α][1,4]diazepin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd92e068ef9c959ec71ac2decf0fe410
https://doi.org/10.1002/ddr.22042
https://doi.org/10.1002/ddr.22042
Autor:
M. S. Rashid Roni, Nicolas M. Zahn, Gene T. Yocum, Daniel A. Webb, Md Yeunus Mian, Michelle J. Meyer, Anika S. Tylek, James M. Cook, Charles W. Emala, Douglas C. Stafford, Leggy A. Arnold
Publikováno v:
Drug Dev Res
MIDD0301 is being developed as an oral drug to relax airway smooth muscle and reduce lung inflammation in asthma. We report a comparative study of MIDD0301 and its S isomer (MIDD0301S) and found that the compounds have equivalent affinity for GABA(A)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40aeb95cbea0d6d642fc7cfe1230d732
https://doi.org/10.1002/ddr.21926
https://doi.org/10.1002/ddr.21926
Autor:
Nicolas M. Zahn, M. S. Rashid Roni, Gene T. Yocum, Michelle J. Meyer, Daniel A. Webb, Md Yeunus Mian, James M. Cook, Douglas C. Stafford, Charles W. Emala, Leggy A. Arnold
Publikováno v:
ACS Pharmacology & Translational Science. 5:80-88
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c51d0f6fe72762c3b66bec25f008718
https://doi.org/10.1021/acsptsci.1c00238
https://doi.org/10.1021/acsptsci.1c00238
Autor:
James Minton Cook, Leggy Arnold, Michelle J Meyer, Nicholas Mark Zahan, Sepideh Rezvanian, Dishary Sharmin, V.V.N. Phani Babu Tiruveedhula, PRITHU MONDAL, Md Yeunus Mian, Lalit Golani, Jeffrey M Witkin, Kamal Prasad Pandey
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::929c6cdd6c3ccb080283a51d79c97dcf
https://doi.org/10.1021/scimeetings.2c00059
https://doi.org/10.1021/scimeetings.2c00059
Autor:
Lalit K. Golani, Branka Divović, Dishary Sharmin, Kamal P. Pandey, Md Yeunus Mian, Rok Cerne, Nicolas M. Zahn, Michelle J. Meyer, Veera V. N. P. B. Tiruveedhula, Jodi L. Smith, Xingjie Ping, Xiaoming Jin, Arnold Lippa, Jeffrey M. Schkeryantz, Leggy A. Arnold, James M. Cook, Miroslav M. Savić, Jeffrey M. Witkin
Publikováno v:
Biopharmaceutics and Drug Disposition
The imidazodiazepine, (5‐(8‐ethynyl‐6‐(pyridin‐2‐yl)‐4H‐benzo [f]imidazole[1,5‐α] [1,4]diazepin‐3‐yl) oxazole or KRM‐II‐81) is a new α2/3‐selective GABAkine (gamma aminobutyric acid A receptor potentiator) with anticonvu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8301324de7bcbbea6f02c7446cb7c5
https://farfar.pharmacy.bg.ac.rs/handle/123456789/4108
https://farfar.pharmacy.bg.ac.rs/handle/123456789/4108
Autor:
Nicolas M, Zahn, M S Rashid, Roni, Gene T, Yocum, Michelle J, Meyer, Daniel A, Webb, Md Yeunus, Mian, James M, Cook, Douglas C, Stafford, Charles W, Emala, Leggy A, Arnold
Publikováno v:
ACS Pharmacol Transl Sci
[Image: see text] We report the modification of MIDD0301, an imidazodiazepine GABA(A) receptor (GABA(A)R) ligand, using two alkyl substituents. We developed PI310 with a 6-(4-phenylbutoxy)hexyl chain as used in the long-acting β2-agonist salmeterol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::80ff30b92baecc5cd39a554926aa329c
https://pubmed.ncbi.nlm.nih.gov/35187417
https://pubmed.ncbi.nlm.nih.gov/35187417
Autor:
Nguyet M. Nguyen, Robert M. Senior, Michelle J. Meyer, Diane G. Kelley, Jeffrey H. Miner, Jessica A. Schlueter
Publikováno v:
Developmental biology. 282(1)
Laminin alpha5 is prominent in the basement membrane of alveolar walls, airways, and pleura in developing and adult lung. Targeted deletion of laminin alpha5 in mice causes developmental defects in multiple organs, but embryonic lethality has preclud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf47a82480afe86459106cbf95caa7d
https://pubmed.ncbi.nlm.nih.gov/15936333
https://pubmed.ncbi.nlm.nih.gov/15936333
Autor:
J. Michael Ruppert, Douglas R. Keene, Michelle J. Meyer, Jeffrey H. Miner, M. Peter Marinkovich, Diane G. Kelley, Gail L. Griffin, Tracy L. Adair-Kirk, Jouni Uitto, Robert M. Senior
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45546 (2012)
PLoS ONE
PLoS ONE
Laminin-332 is a heterotrimeric basement membrane component comprised of the α3, ß3, and γ2 laminin chains. Laminin-332 modulates epithelial cell processes, such as adhesion, migration, and differentiation and is prominent in many embryonic and ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd489bb3395a04633ca36bbdaaa182a
https://doi.org/10.1371/journal.pone.0045546
https://doi.org/10.1371/journal.pone.0045546