Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Michelle Hof"'
Autor:
Martin Christa, Franziska Dithmar, Tobias Weinaus, Michael Kohlhaas, Anahi-Paula Arias-Loza, Michelle Hofmann, Ibrahim A. Elabyad, Fabian T. Gutjahr, Christoph Maack, Wolfgang R. Bauer
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Cardiac myocyte sodium (Na+) homoeostasis is pivotal in cardiac diseases and heart failure. Intracellular Na+ ([Na+]i) is an important regulator of excitation–contraction coupling and mitochondrial energetics. In addition, extracellular Na
Externí odkaz:
https://doaj.org/article/d9de801c74594940856816ea78bd9281
Autor:
Stephanie-Michelle Hof, René-Maxime Gracien, Sergiu Groppa, Amgad Droby, Vinzenz Fleischer, Mathias Wahl, Sarah C. Reitz, Ralf Deichmann, Johannes C. Klein, Helmuth Steinmetz
Publikováno v:
Journal of Magnetic Resonance Imaging. 46:1485-1490
PURPOSE Quantitative MRI (qMRI) allows assessing cortical pathology in multiple sclerosis (MS) on a microstructural level, where cortical damage has been shown to prolong T1 -relaxation time and increase proton density (PD) compared to controls. Howe
Autor:
René-Maxime Gracien, Ralf Deichmann, Vinzenz Fleischer, Christoph Mayer, Sergiu Groppa, Steffen Volz, Sarah C. Reitz, Johannes C. Klein, Marlies Wagner, Helmuth Steinmetz, Elke Hattingen, Stephanie-Michelle Hof, Amgad Droby
Publikováno v:
Magnetic Resonance Materials in Physics, Biology and Medicine. 30:75-83
Proton density (PD) mapping requires correction for the receive profile (RP), which is frequently performed via bias-field correction. An alternative RP-mapping method utilizes a comparison of uncorrected PD-maps and a value ρ(T1) directly derived f
Autor:
Helmuth Steinmetz, Sarah C. Reitz, Rüdiger Hilker-Roggendorf, Johannes C. Klein, Simon Baudrexel, Stephanie-Michelle Hof, Pavel Hok, Lucas Nürnberger, René-Maxime Gracien, Ralf Deichmann, Udo Rüb
Publikováno v:
European Radiology. 27:1568-1576
T1 relaxometry is a promising tool for the assessment of microstructural changes during brain ageing. Previous cross-sectional studies demonstrated increasing T1 values in white and decreasing T1 values in grey matter over the lifetime. However, thes
Autor:
Marlies Wagner, Sarah C. Reitz, Vinzenz Fleischer, Amgad Droby, Steffen Volz, Stephanie-Michelle Hof, Ralf Deichmann, Christoph Mayer, Alina Jurcoane, René-Maxime Gracien, Johannes C. Klein, Sergiu Groppa, Helmuth Steinmetz, Elke Hattingen
Publikováno v:
Journal of Magnetic Resonance Imaging. 44:1600-1607
Purpose To investigate magnetization transfer ratio (MTR), T1 relaxation time, and proton density (PD) as indicators of gray matter damage in relapsing-remitting multiple sclerosis (RRMS), reflecting different aspects of microstructural damage and as
Autor:
Sarah C. Reitz, Adriane Gröger, René-Maxime Gracien, Johannes C. Klein, Frauke Zipp, Helmuth Steinmetz, Stephanie-Michelle Hof, Alla Brodski, Amgad Droby, Ulf Ziemann, Ralf Deichmann, Vinzenz Fleischer
Publikováno v:
Brain Imaging and Behavior. 11:744-753
White matter (WM) lesions with a distinct lesion-tissue contrast are the main radiological hallmark of multiple sclerosis (MS) in standard magnetic resonance imaging (MRI). Pathological WM changes beyond lesion development lack suitable contrasts, re
Autor:
Amgad Droby, Hilga Zimmermann, Sarah C. Reitz, Johannes C. Klein, Helmuth Steinmetz, Stephanie-Michelle Hof, Vinzenz Fleischer, Frauke Zipp, René-Maxime Gracien, Ralf Deichmann
Publikováno v:
NMR in Biomedicine. 29:444-450
T2 relaxation time is a quantitative MRI in vivo surrogate of cerebral tissue damage in multiple sclerosis (MS) patients. Cortical T2 prolongation is a known feature in later disease stages, but has not been demonstrated in the cortical normal appear
Autor:
Johannes C. Klein, René-Maxime Gracien, Sarah C. Reitz, Hilga Zimmermann, Vinzenz Fleischer, Stephanie Michelle Hof, Amgad Droby, Ralf Deichmann, Simon Baudrexel
Publikováno v:
NMR in Biomedicine. 29:349-360
Quantitative T1 mapping of brain tissue is frequently based on the variable flip angle (VFA) method, acquiring spoiled gradient echo (GE) datasets at different excitation angles. However, accurate T1 calculation requires a knowledge of the sensitivit
Autor:
Johannes C. Klein, Stephanie-Michelle Hof, Simon Baudrexel, Helmuth Steinmetz, René-Maxime Gracien, Ralf Deichmann, Lucas Nürnberger, Pavel Hok, Rüdiger Hilker, Udo Rüb
Publikováno v:
NeuroImage: Clinical, Vol 13, Iss C, Pp 405-414 (2017)
NeuroImage : Clinical
NeuroImage : Clinical
Background Histological evidence suggests that pathology in Parkinson's disease (PD) goes beyond nigrostriatal degeneration and also affects the cerebral cortex. Quantitative MRI (qMRI) techniques allow the assessment of changes in brain tissue compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b8c972e6e54ff4eb7a9a41b69fb075
http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/43246
http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/43246
Autor:
René-Maxime, Gracien, Sarah C, Reitz, Stephanie-Michelle, Hof, Vinzenz, Fleischer, Amgad, Droby, Mathias, Wahl, Helmuth, Steinmetz, Sergiu, Groppa, Ralf, Deichmann, Johannes C, Klein
Publikováno v:
Journal of magnetic resonance imaging : JMRI. 46(5)
Quantitative MRI (qMRI) allows assessing cortical pathology in multiple sclerosis (MS) on a microstructural level, where cortical damage has been shown to prolong TTwelve patients with relapsing-remitting MS underwent 3T TStatistical analysis showed