Evaluation of diagnostic assays for the serological detection of Actinobacillus pleuropneumoniae on samples of known or unknown exposure

Autor: Patrick G. Halbur, Kyoung-Jin Yoon, Michelle Hemann, John K. Johnson, Luis G. Giménez-Lirola, Hai Hoang, Marcelo Gottschalk, Kevin O'Neill, Sheila Heinen, Tanja Opriessnig

Publikováno v: Journal of Veterinary Diagnostic Investigation. 25:61-71

Accurate diagnosis of exposure to Actinobacillus pleuropneumoniae is important for maintaining negative farms. In the present study, the ability of a dual-plate complement fixation (CF) assay and 3 commercially available enzyme-linked immunosorbent a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9f8191c4855aaf737b4160c9cf3363f
https://doi.org/10.1177/1040638712469607

Expression of human CD46 has no effect on porcine circovirus type 2 infection and shedding in the experimental pig model

Autor: Xiang-Jin Meng, Patrick G. Halbur, Nathan M. Beach, Michelle Hemann, Tanja Opriessnig, Huigang Shen

Publikováno v: Veterinary Research Communications. 36:187-193

Xenotransplantation of tissues from transgenic pigs with desired genetic modifications such as CD46 expression help minimize xenograft rejections. However, CD46 is a known receptor for some viruses. In this study, pigs transgenic for human CD46 (CD46

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c8949607a29cfa6da2acefbd0eb55df
https://doi.org/10.1007/s11259-012-9524-z

Studies on Porcine Circovirus Type 2 Vaccination of 5-Day-Old Piglets

Autor: Nathan M. Beach, Tanja Opriessnig, Xiang-Jin Meng, Kevin O'Neill, Michelle Hemann, Kathy Lin, Huigang Shen, P. G. Halbur

Publikováno v: O'Neill, K C, Shen, H G, Lin, K, Hemann, M, Beach, N M, Meng, X J, Halbur, P G & Opriessnig, T 2011, ' Studies on porcine circovirus type 2 vaccination of 5-day-old piglets ', Clinical and Vaccine Immunology, vol. 18, no. 11, pp. 1865-71 . https://doi.org/10.1128/CVI.05318-11

Porcine circovirus type 2 (PCV2) vaccines have become widely used since they became available in 2006. It is not uncommon for producers to use PCV2 vaccines in pigs younger than what is approved by manufacturers. The objective of this study was to de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df60e4b88843ac8774b78433375d3dba
https://doi.org/10.1128/cvi.05318-11

ORF1 but not ORF2 dependent differences are important for in vitro replication of PCV2 in porcine alveolar macrophages singularly or coinfected with PRRSV

Autor: Carmen Ledesma, Nathan M. Beach, Avanti Sinha, Kathy Lin, Tanja Opriessnig, Xiang-Jin Meng, Patrick G. Halbur, Huigang Shen, Chong Wang, Michelle Hemann

Publikováno v: Veterinary microbiology. 158(1-2)

The objective of this study was to investigate cytokine expression and in vitro replication of porcine circovirus type 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV) in pulmonary alveolar macrophages (PAMs) emphasizing PCV2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afacfe9faea306a97c7edb60b6def13c
https://pubmed.ncbi.nlm.nih.gov/22406345