Bisphenol A Does Not Mimic Estrogen in the Promotion of the In Vitro Response of Murine Dendritic Cells to Toll-Like Receptor Ligands

Autor: Marita Chakhtoura, Uma Sriram, Michelle Heayn, Joshua Wonsidler, Christopher Doyle, Joudy-Ann Dinnall, Stefania Gallucci, Rebecca A. Roberts

Publikováno v: Mediators of Inflammation, Vol 2017 (2017)

Sex hormones affect immune responses and might promote autoimmunity. Endocrine disrupting chemicals such as bisphenol A (BPA) may mimic their immune effects. Conventional dendritic cells (cDCs) are pivotal initiators of immune responses upon activati

Externí odkaz: https://doaj.org/article/f49cf92498754be8a6da1ab4604a4c1f

Impact of Ki-67 Labeling Index on Prognostic Significance of the Chemotherapy Response Score in Women With Tubo-ovarian Cancer Treated With Neoadjuvant Chemotherapy

Autor: Li Zhu, Lauren B Skvarca, Esther Elishaev, Francesmary Modugno, Alexander B. Olawaiye, Rohit Bhargava, Robert P. Edwards, Michelle Heayn

Publikováno v: International Journal of Gynecological Pathology. 40:278-285

The chemotherapy response score (CRS) proposed by Bohm and colleagues in 2015 has been validated as a reproducible method for determining histopathologic response of tubo-ovarian carcinoma to neoadjuvant chemotherapy and stratifies tumor response int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31c9d3804f19fffde233bd2bbabe130d
https://doi.org/10.1097/pgp.0000000000000706

Non-functional pancreatic neuroendocrine tumours

Autor: You Na Sung, Michele Milella, Herbert J. Zeh, Muaz Aijazi, Jacqueline A. Brosnan-Cashman, Claudio Luchini, Rita T. Lawlor, Alessandro Paniccia, Michael A. Nalesnik, Aatur D. Singhi, Asif Khalid, Roberto Salvia, Koen M.A. Dreijerink, Massimo Milione, Lodewijk A.A. Brosens, G. Johan A. Offerhaus, Nathan Bahary, Melissa E. Hogg, Soyeon An, Marina N. Nikiforova, Ta-Chiang Liu, Samantha Bersani, Harkirat Singh, Savreet Sarkaria, Randall E. Brand, Charlotte M. Heidsma, Wenzel M. Hackeng, Folkert H.M. Morsink, Joo Young Kim, Seung-Mo Hong, Boris Rusev, Adam Slivka, David A. Geller, Kenneth K.W. Lee, Melanie Ongchin, Kenneth E. Fasanella, James F. Pingpank, Sara Cingarlini, Aldo Scarpa, Els J. M. Nieveen van Dijkum, Andrea Mafficini, Rohit Das, Antonio Pea, Menno R. Vriens, Vincenzo Corbo, Luca Landoni, Amer H. Zureikat, Gerlof D. Valk, Roderick J. O’Sullivan, J. Wallis Marsh, Xiaoli Han, Kevin McGrath, Jennifer Chennat, Michelle Heayn, Dengfeng Cao, Christopher M. Heaphy

Publikováno v: Hackeng, W M, Brosens, L A A, Kim, J Y, O'Sullivan, R, Sung, Y N, Liu, T C, Cao, D, Heayn, M, Brosnan-Cashman, J, An, S, Morsink, F H M, Heidsma, C M, Valk, G D, Vriens, M R, Nieveen Van Dijkum, E, Offerhaus, G J A, Dreijerink, K M A, Zeh, H, Zureikat, A H, Hogg, M, Lee, K, Geller, D, Marsh, J W, Paniccia, A, Ongchin, M, Pingpank, J F, Bahary, N, Aijazi, M, Brand, R, Chennat, J, Das, R, Fasanella, K E, Khalid, A, McGrath, K, Sarkaria, S, Singh, H, Slivka, A, Nalesnik, M, Han, X, Nikiforova, M N, Lawlor, R T, Mafficini, A, Rusev, B, Corbo, V, Luchini, C, Bersani, S, Pea, A, Cingarlini, S, Landoni, L, Salvia, R, Milione, M, Milella, M, Scarpa, A, Hong, S M, Heaphy, C M & Singhi, A D 2021, ' Non-functional pancreatic neuroendocrine tumours : ATRX/DAXX and alternative lengthening of telomeres (ALT) are prognostically independent from ARX/PDX1 expression and tumour size ', Gut . https://doi.org/10.1136/gutjnl-2020-322595
Gut. BMJ Publishing Group

ObjectiveRecent studies have found aristaless-related homeobox gene (ARX)/pancreatic and duodenal homeobox 1 (PDX1), alpha-thalassemia/mental retardation X-linked (ATRX)/death domain-associated protein (DAXX) and alternative lengthening of telomeres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e02f79ca49171f43f7a10892f04e5b6
http://www.scopus.com/inward/record.url?scp=85104459455&partnerID=8YFLogxK

PECAM-1 and caveolae form the mechanosensing complex necessary for NOX2 activation and angiogenic signaling with stopped flow in pulmonary endothelium

Autor: Shampa Chatterjee, Horace M. DeLisser, Hui Wang, Nankang Hong, Kristine Debolt, Michelle Heayn, John Noel, Victor Rizzo, Jian-Qin Tao, Aron B. Fisher, Elena M. Sorokina, Kevin Yu

Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology. 305:L805-L818

We showed that stop of flow triggers a mechanosignaling cascade that leads to the generation of reactive oxygen species (ROS); however, a mechanosensor coupled to the cytoskeleton that could potentially transduce flow stimulus has not been identified

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::109610c9082b885166832373cccfaacb
https://doi.org/10.1152/ajplung.00123.2013