Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Michelle H. Lewin"'
Autor:
Robert Hume, Michelle H. Lewin, S W Walker, Kerry Richard, A F Howie, Geoffrey J. Beckett, Fergus Nicol, John R. Arthur
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1526:237-241
Cytosolic thioredoxin reductase (TR) is an FAD-containing homodimeric selenoenzyme which, together with thioredoxin (Trx) and NADPH, forms a powerful oxidoreductase system. Cytoplasmic glutathione peroxidase (GPX-1) is a selenoprotein with antioxidan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::129ca5c5aeb65aaa0b443dbfa27256df
https://doi.org/10.1016/s0304-4165(01)00133-7
https://doi.org/10.1016/s0304-4165(01)00133-7
Autor:
Michelle H. Lewin, Richard Bowman, Nina Bailey, Sheila Bingham, Amanda J. Cross, David E. G. Shuker, Tanya Bandaletova, J.R.A. Pollock
Publikováno v:
Cancer research. 66(3)
Red meat is associated with increased risk of colorectal cancer and increases the endogenous formation of N-nitrosocompounds (NOC). To investigate the genotoxic effects of NOC arising from red meat consumption, human volunteers were fed high (420 g)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab9bdccd5261081e2ecb9504bc16ea30
https://pubmed.ncbi.nlm.nih.gov/16452248
https://pubmed.ncbi.nlm.nih.gov/16452248
Autor:
Michelle H. Lewin, Fergus Nicol, Alexander F. Howie, Rudolph A. Riemersma, Geoffrey J. Beckett, S W Walker, E. Margaret Millar, John R. Arthur
Publikováno v:
Lewin, M H, Arthur, J R, Riemersma, R A, Nicol, F, Walker, S W, Millar, E M, Howie, A F & Beckett, G J 2002, ' Selenium supplementation acting through the induction of thioredoxin reductase and glutathione peroxidase protects the human endothelial cell line EAhy926 from damage by lipid hydroperoxides ', BBA-Biomembranes, vol. 1593, no. 1, pp. 85-92 . https://doi.org/10.1016/S0167-4889(02)00333-6
The human endothelial cell line EAhy926 was used to determine the importance of selenium in preventing oxidative damage induced by tert-butyl hydroperoxide (tert-BuOOH) or oxidised low density lipoprotein (LDLox). In cells grown in a low selenium med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5955d740cf99b4987a43271d867795be
https://hdl.handle.net/20.500.11820/20783332-f85e-4460-a7d8-959fbf2bb6f7
https://hdl.handle.net/20.500.11820/20783332-f85e-4460-a7d8-959fbf2bb6f7
Autor:
Michelle H. Lewin, A F Howie, Karen Pickard, S W Walker, John R. Arthur, S. M. Miller, Fergus Nicol, Geoffrey J. Beckett
Publikováno v:
Miller, S, Walker, S W, Arthur, J R, Lewin, M H, Pickard, K, Nicol, F, Howie, A F & Beckett, G J 2002, ' Selenoprotein expression in endothelial cells from different human vasculature and species ', BBA-Biomembranes, vol. 1588, no. 1, pp. 85-93 . https://doi.org/10.1016/S0925-4439(02)00143-6
Selenium (Se) can protect endothelial cells (EC) from oxidative damage by altering the expression of selenoproteins with antioxidant function such as cytoplasmic glutathione peroxidase (cyGPX), phospholipid hydroperoxide glutathione peroxidase (PHGPX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2b27d11cd3ad302ded15c5233fdd0e0
https://hdl.handle.net/20.500.11820/51d67b4e-3454-4810-aef8-091b3733c534
https://hdl.handle.net/20.500.11820/51d67b4e-3454-4810-aef8-091b3733c534
Autor:
Fergus Nicol, John R. Arthur, Sue Miller, Geoffrey J. Beckett, Michelle H. Lewin, Karen Pickard, A. Forbes Howie, Simon W. Walker
Publikováno v:
Clinical Science. 100:543
The ability of selenium to protect cultured human coronary artery endothelial cells (HCAEC), human umbilical vein endothelial cells (HUVEC) and bovine aortic endothelial cells (BAEC) from oxidative damage induced by 100 μM t-butyl hydroperoxide (t-B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b88d09dad7e0ca831fe5ab48979f0947
https://doi.org/10.1042/cs20000299
https://doi.org/10.1042/cs20000299