Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Michelle Gumz"'
Autor:
Hannah Costello, G. Ryan Crislip, Annalisse Mckee, Kit-Yan Cheng, Alexandria Juffre, Jermaine Johnstone, Lauren Douma, Michelle Gumz
Publikováno v:
Physiology. 38
Circadian rhythms are 24-hour oscillations that regulate many physiological functions including hormone signaling and electrolyte excretion. These rhythms are coordinated by a molecular clock, comprised of 4 key core clock proteins – BMAL1, CLOCK,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d385dca03e45b841222873cd584d535
https://doi.org/10.1152/physiol.2023.38.s1.5731958
https://doi.org/10.1152/physiol.2023.38.s1.5731958
Publikováno v:
Physiology. 38
The circadian clock protein BMAL1 is a core component of the intrinsic molecular clock mechanism that governs circadian rhythms. We use a kidney-specific Bmal1 knockout mouse model (KS-BMAL1KO) with loss of BMAL1 expression in the distal segments of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdabe2c1edeeebff77fc693ed3d38421
https://doi.org/10.1152/physiol.2023.38.s1.5734912
https://doi.org/10.1152/physiol.2023.38.s1.5734912
Autor:
Hannah Costello, Kit-Yan Cheng, Jermaine Johnstone, Alexandria Juffre, Lauren Douma, Michelle Gumz, G. Ryan Crislip
Publikováno v:
Physiology. 38
Clinical studies demonstrate that women have exacerbated salt-sensitive blood pressure (BP) responses compared to men. However, most studies examining the molecular mechanisms involved in salt-sensitive hypertension focus on males. Accumulating evide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::077f817c88cf69fb891937639fb40e0a
https://doi.org/10.1152/physiol.2023.38.s1.5734672
https://doi.org/10.1152/physiol.2023.38.s1.5734672
Publikováno v:
Physiology. 38
Circadian rhythm in the body is regulated through a central clock in the brain signaling through molecular clocks in the peripheral tissue. PER1, CRY, CLOCK, and BMAL1 are the 4 genes regulating the mechanism of the molecular clock. It has been estab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9359af331ef0be7b03e8e915f0b48a79
https://doi.org/10.1152/physiol.2023.38.s1.5730360
https://doi.org/10.1152/physiol.2023.38.s1.5730360
Autor:
Ann Thomas, Nishka R. Jakkidi, Shiyu Li, Kit‐Yan Cheng, Michelle Gumz, Muna T. Canales, Rajesh Mohandas
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::234c9baa9d1db1629c7f60b2b64aa5d0
https://doi.org/10.1096/fasebj.2022.36.s1.r5403
https://doi.org/10.1096/fasebj.2022.36.s1.r5403