Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Michelle Grilley"'
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73843 (2013)
A novel aminoglycoside, FG08, that differs from kanamycin B only by a C8 alkyl chain at the 4″-O position, was previously reported. Unlike kanamycin B, FG08 shows broad-spectrum fungicidal but not anti-bacterial activities. To understand its specif
Externí odkaz:
https://doaj.org/article/7f65924c159b4976bf304461669565cd
Autor:
Yukie Kawasaki, Jon Y. Takemoto, Michelle Grilley, Madher N. Alfindee, Qian Zhang, Cheng-Wei Tom Chang, Jaya P. Shrestha, Yagya Prasad Subedi
Publikováno v:
Bioorganic & Medicinal Chemistry. 26:765-774
Carbohydrate esters are biodegradable, and the degraded adducts are naturally occurring carbohydrates and fatty acids which are environmentally friendly and non-toxic to human. A simple one-step regioselective acylation of mono-carbohydrates has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8444d0cf43562d79d4be559cf17442d3
https://doi.org/10.1016/j.bmc.2017.12.038
https://doi.org/10.1016/j.bmc.2017.12.038
Autor:
Jon Y. Takemoto, Yagya Prasad Subedi, Michelle Grilley, Madher N. Alfindee, Cheng-Wei Tom Chang
Publikováno v:
Biology Faculty Publications
Molecules
Volume 24
Issue 10
Molecules, Vol 24, Iss 10, p 1882 (2019)
Molecules
Volume 24
Issue 10
Molecules, Vol 24, Iss 10, p 1882 (2019)
Amphiphilic kanamycins derived from the classic antibiotic kanamycin have attracted interest due to their novel bioactivities beyond inhibition of bacteria. In this study, the recently described 4&Prime
6&Prime
diaryl amphiphilic kanamycins
6&Prime
diaryl amphiphilic kanamycins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd673a82685ddab25aa93fe793f0ce2
https://digitalcommons.usu.edu/cgi/viewcontent.cgi?article=2691&context=biology_facpub
https://digitalcommons.usu.edu/cgi/viewcontent.cgi?article=2691&context=biology_facpub
Publikováno v:
ACS infectious diseases. 5(3)
Amphiphilic aminoglycosides have attracted interest due to their novel antifungal activities. A crucial but often neglected factor for drug development in academia is cost of production. Herein is reported a one-step, inexpensive synthesis of amphiph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c049bc6f7f534f32e7bd7887254daaf
https://pubmed.ncbi.nlm.nih.gov/30674192
https://pubmed.ncbi.nlm.nih.gov/30674192
Autor:
Jon Y. Takemoto, Michelle Grilley, Justin A. Jones, Yukie Kawasaki, Claudia Nischwitz, Jason D. Brown
Publikováno v:
Journal of Phytopathology. 164:801-810
Syringomycin E (SRE) is a cyclic lipodepsinonapeptide with potent antifungal activity and is produced by certain strains of Pseudomonas syringae pv. syringae. In this study, its potential as an organic-compatible agrofungicide and vegetable seed trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbe3634c59180896ee603ff11d6790c1
https://doi.org/10.1111/jph.12500
https://doi.org/10.1111/jph.12500
Autor:
Jaya P. Shrestha, Greg Becker, Jon Y. Takemoto, Michelle Grilley, Yagya Prasad Subedi, Madher N. Alfindee, Cheng-Wei Tom Chang
Publikováno v:
Bioorganicmedicinal chemistry letters. 28(18)
Phosphonates, azoles and quinones are pharmacophores found in bioactive compounds. A series of phosphonates conjugated to azoles and quinones with variable carbon chain lengths were synthesized in 3-4 steps with good yield. Antifungal assay of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c944bb409e2b3d64c9a973ab093545
https://pubmed.ncbi.nlm.nih.gov/30093296
https://pubmed.ncbi.nlm.nih.gov/30093296
Publikováno v:
Green Chemistry. 17:1918-1925
A library of fifteen commercially purchased and synthetic fluorogenic probes was employed for the investigation of biomass degradation using extracts of white-rot fungi. These probes were selected or designed to mimic the dominant linkages in cellulo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::882160a73d0b89e7a92f207cf7757a73
https://doi.org/10.1039/c4gc01659a
https://doi.org/10.1039/c4gc01659a
Autor:
Michelle Grilley, David R. Hillyard, Maren Watkins, Lourdes J. Cruz, Elsie C. Jimenez, Baldomero M. Olivera, Richard B. Jacobsen
Publikováno v:
The Journal of Peptide Research. 51:173-179
We previously characterized contryphan-R, a D-tryptophan-containing octapeptide from the venom of Conus radiatus. In this study, we present evidence that the contryphan family of peptides is widely distributed in venoms of the fish-hunting cone snail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d98d8145be12a63d92404452296b7dc7
https://doi.org/10.1111/j.1399-3011.1998.tb01213.x
https://doi.org/10.1111/j.1399-3011.1998.tb01213.x
Autor:
Jon Y. Takemoto, Michelle Grilley, Nicole Meissner, John Oblad, Kevin N. Sorensen, Cheng-Wei Tom Chang, Jaya P. Shrestha, Sanjib K. Shrestha
Publikováno v:
Frontiers in Microbiology, Vol 5 (2014)
Frontiers in Microbiology
Chemistry and Biochemistry Faculty Publications
Frontiers in Microbiology
Chemistry and Biochemistry Faculty Publications
K20 is a novel amphiphilic antifungal aminoglycoside that is synthetically derived from the antibiotic kanamycin A. Reported here are investigations of K20’s antimicrobial activities, cytotoxicity, and fungicidal mechanism of action. In vitro growt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb8ea09e8c15c0be5b07bc97432b2c6c
http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00671/full
http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00671/full
Publikováno v:
FEBS Letters. 569:272-276
Sphingoid base C4 hydroxylation is required for syringomycin E action on the yeast plasma membrane. Detergent-insoluble glycolipid-enriched membranes (DIGs) from a yeast strain lacking C4 hydroxylated sphingoid bases (sur2Δ) are composed of linear m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::447538a3f970ba436885f86cb34608f8
https://doi.org/10.1016/j.febslet.2004.05.074
https://doi.org/10.1016/j.febslet.2004.05.074