Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Michelle G Pedler"'
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0248545 (2021)
IntroductionCerebrospinal fluid (CSF) outflow has been demonstrated along nasal lymphatics via olfactory nerve projections; flow may be increased by stimulating lymphatic contractility using agents such as noradrenaline and the thromboxane A2 analog
Externí odkaz:
https://doaj.org/article/2c0d5b7c1f064f17958d0ac93826e055
Autor:
Niklaus H Mueller, Uma Fogueri, Michelle G Pedler, Kameron Montana, J Mark Petrash, David A Ammar
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137659 (2015)
Misfolded protein aggregation, including cataract, cause a significant amount of blindness worldwide. α-Crystallin is reported to bind misfolded proteins and prevent their aggregation. We hypothesize that supplementing retina and lens with α-crysta
Externí odkaz:
https://doaj.org/article/b0ee6cfd8adf4645998826edd0cecb0c
Autor:
Michelle G. Pedler, Jeffrey L. Olson, Joshua L. Morgenstern, Anthony A. Jones, Divneet Mandair
Publikováno v:
RETINAL Cases & Brief Reports. 16:515-519
To present a case of idiopathic retinal vasculitis, aneurysms, and neuroretinitis syndrome that was successfully managed with serial intravitreal aflibercept injections.Ophthalmic imaging and visual acuity were used to monitor disease state and track
Autor:
Michelle G. Pedler, Carson C. Petrash, Brandie D. Wagner, Alan G. Palestine, Biehuoy Shieh, Anne M. Lynch, Karen L Christopher, Jennifer L. Patnaik, Naresh Mandava, J. Mark Petrash
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose To determine the effect of metformin on early Nd:YAG laser treatment for posterior capsule opacification (PCO) and to explore a molecular mechanism to explain a possible protective effect of metformin against PCO. Methods We conducted: 1) a r
Publikováno v:
Biomolecules
Biomolecules, Vol 11, Iss 1150, p 1150 (2021)
Volume 11
Issue 8
Biomolecules, Vol 11, Iss 1150, p 1150 (2021)
Volume 11
Issue 8
Cataracts are a leading cause of blindness worldwide. Surgical removal of cataracts is a safe and effective procedure to restore vision. However, a large number of patients later develop vision loss due to regrowth of lens cells and subsequent degrad
Autor:
Dongyan Wang, Biehuoy Shieh, Matthew L. Hupy, Xiao-Jing Wang, Michelle G. Pedler, J. Mark Petrash
Publikováno v:
Chem Biol Interact
Cataracts, a clouding of the eye lens, are a leading cause of visual impairment and are responsible for one of the most commonly performed surgical procedures worldwide. Although generally safe and effective, cataract surgery can lead to a secondary
Autor:
Zhe Chen, Harald J. Junge, Ralf H. Adams, Michelle G. Pedler, Chi Zhang, Maria B. Lai, J. Mark Petrash, Verity Johnson
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Supplemental Digital Content is available in the text.
Objective— Blood-CNS (central nervous system) barrier defects are implicated in retinopathies, neurodegenerative diseases, stroke, and epilepsy, yet, the pathological mechanisms downstream
Objective— Blood-CNS (central nervous system) barrier defects are implicated in retinopathies, neurodegenerative diseases, stroke, and epilepsy, yet, the pathological mechanisms downstream
Autor:
Kevin Chyung, Michelle G. Pedler, Biehuoy Shieh, Patricia Lenhart, Leonid M. Zukin, Sarah Seiwald, J. Mark Petrash
Publikováno v:
Chem Biol Interact
After cataract surgery, epithelial cells lining the anterior lens capsule can transition to one of two divergent pathways, including fibrosis which leads to posterior capsular opacification (PCO), or lens fiber cell differentiation which leads to reg
Autor:
Mina B. Pantcheva, Michelle G. Pedler, J. Mark Petrash, Sergio Groman-Lupa, Leonid M. Zukin, David A. Ammar
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Cataract surgery is a procedure by which the lens fiber cell mass is removed from its capsular bag and replaced with a synthetic intraocular lens. Postoperatively, remnant lens epithelial cells can undergo an aberrant wound healing response c
Autor:
Karen R. Jonscher, Michelle G. Pedler, Diana Fulan Yang, Carl K. Edwards, Mayumi Fujita, James E. Fitzpatrick, David A. Norris
Publikováno v:
Psoriasis Forum. :126-141
Psoriasis is a chronic inflammatory skin disease that affects 2.2% of Americans and is a substantial detriment on the quality of life. Psoriasis is a complex interaction between numerous immune cells and has been considered largely a T-helper type 1