Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Michelle F. Motta"'
Autor:
Murilo M. Pedrote, Michelle F. Motta, Giulia D.S. Ferretti, Douglas R. Norberto, Tania C.L.S. Spohr, Flavia R.S. Lima, Enrico Gratton, Jerson L. Silva, Guilherme A.P. de Oliveira
Publikováno v:
iScience, Vol 23, Iss 2, Pp - (2020)
Summary: Tumor-associated p53 mutations endow cells with malignant phenotypes, including chemoresistance. Amyloid-like oligomers of mutant p53 transform this tumor suppressor into an oncogene. However, the composition and distribution of mutant p53 o
Externí odkaz:
https://doaj.org/article/8a4bf5adff4744ea82b083a4f6cf2df5
Autor:
Tania Cristina Leite de Sampaio e Spohr, Douglas R. Norberto, Murilo M. Pedrote, Jerson L. Silva, Guilherme A. P. de Oliveira, Enrico Gratton, Flavia Regina Souza Lima, Michelle F. Motta, Giulia D. S. Ferretti
Publikováno v:
iScience, Vol 23, Iss 2, Pp-(2020)
iScience
iScience, vol 23, iss 2
iScience
iScience, vol 23, iss 2
Summary Tumor-associated p53 mutations endow cells with malignant phenotypes, including chemoresistance. Amyloid-like oligomers of mutant p53 transform this tumor suppressor into an oncogene. However, the composition and distribution of mutant p53 ol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24334a83398ce94c5fdfc7711adee264
http://www.sciencedirect.com/science/article/pii/S2589004220300031
http://www.sciencedirect.com/science/article/pii/S2589004220300031
Amyloid Oligomers of Mutant p53 in Living Cells Result in Oncogenic Gain of Function in Glioblastoma
Autor:
Murilo M. Pedrote, Guilherme A. P. de Oliveira, Enrico Gratton, Jerson L. Silva, Flavia Regina Souza Lima, Douglas R. Norberto, Tania Cristina Leite de Sampaio e Spohr, Michelle F. Motta
Publikováno v:
SSRN Electronic Journal.
Tumor-associated p53 mutations endow cells with malignant phenotypes, including chemoresistance to standard treatments. Amyloid-like oligomeric species of mutant p53 have been attributed to transformation of the p53 tumor suppressor into an oncogene.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c490811cad000806e4e06a0900b297dc
https://doi.org/10.2139/ssrn.3445669
https://doi.org/10.2139/ssrn.3445669