Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Michelle E. Stewart"'
Autor:
Gemma F. Codner, Joffrey Mianné, Adam Caulder, Jorik Loeffler, Rachel Fell, Ruairidh King, Alasdair J. Allan, Matthew Mackenzie, Fran J. Pike, Christopher V. McCabe, Skevoulla Christou, Sam Joynson, Marie Hutchison, Michelle E. Stewart, Saumya Kumar, Michelle M. Simon, Loranne Agius, Quentin M. Anstee, Kirill E. Volynski, Dimitri M. Kullmann, Sara Wells, Lydia Teboul
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-16 (2018)
Abstract Background Recent advances in clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) genome editing have led to the use of long single-stranded DNA (lssDNA) molecules for generating conditional
Externí odkaz:
https://doaj.org/article/ee1cca96cdab4bc9a1b2e27269d0610a
Loss of arylformamidase with reduced thymidine kinase expression leads to impaired glucose tolerance
Autor:
Alison J. Hugill, Michelle E. Stewart, Marianne A. Yon, Fay Probert, I. Jane Cox, Tertius A. Hough, Cheryl L. Scudamore, Liz Bentley, Gary Wall, Sara E. Wells, Roger D. Cox
Publikováno v:
Biology Open, Vol 4, Iss 11, Pp 1367-1375 (2015)
Tryptophan metabolites have been linked in observational studies with type 2 diabetes, cognitive disorders, inflammation and immune system regulation. A rate-limiting enzyme in tryptophan conversion is arylformamidase (Afmid), and a double knockout o
Externí odkaz:
https://doaj.org/article/0d46b7420e604bf78174db331289ed60
Autor:
Christopher V McCabe, Peter D Price, Gemma F Codner, Alasdair J Allan, Adam Caulder, Skevoulla Christou, Jorik Loeffler, Matthew Mackenzie, Elke Malzer, Joffrey Mianné, Krystian J Nowicki, Edward J O'Neill, Fran J Pike, Marie Hutchison, Benoit Petit-Demoulière, Michelle E Stewart, Hilary Gates, Sara Wells, Nicholas D Sanderson, Lydia Teboul
Publikováno v:
PLoS Genetics, Vol 20, Iss 3, p e1011187 (2024)
BackgroundRecent developments in CRISPR/Cas9 genome-editing tools have facilitated the introduction of precise alleles, including genetic intervals spanning several kilobases, directly into the embryo. However, the introduction of donor templates, vi
Externí odkaz:
https://doaj.org/article/bb312da1ed8649b9bf1f17a2c3bba609
Autor:
Muriel Thoby-Brisson, Julien Bouvier, Derrick M Glasco, Michelle E Stewart, Charlotte Dean, Jennifer N Murdoch, Jean Champagnat, Gilles Fortin, Anand Chandrasekhar
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31140 (2012)
The proper development and maturation of neuronal circuits require precise migration of component neurons from their birthplace (germinal zone) to their final positions. Little is known about the effects of aberrant neuronal position on the functioni
Externí odkaz:
https://doaj.org/article/616b6ba8dfe244c9ab9ef7793ca49140