Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Michelle E. Casper"'
Publikováno v:
Journal of Orthopaedic Research
There is controversy over whether bone or cartilage is primarily involved in osteoarthritis (OA) pathogenesis; this is important for targeting early interventions. We explored evidence from animal models of knee OA by preforming a systematic review o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb59938da11f15014f9266b9493f63f
http://europepmc.org/articles/PMC7383628
http://europepmc.org/articles/PMC7383628
Autor:
David F Razidlo, Tiffany J Whitney, Michelle E Casper, Meghan E McGee-Lawrence, Bridget A Stensgard, Xiaodong Li, Frank J Secreto, Sarah K Knutson, Scott W Hiebert, Jennifer J Westendorf
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11492 (2010)
Histone deacetylase (Hdac)3 is a nuclear enzyme that contributes to epigenetic programming and is required for embryonic development. To determine the role of Hdac3 in bone formation, we crossed mice harboring loxP sites around exon 7 of Hdac3 with m
Externí odkaz:
https://doaj.org/article/782d7d2bcd6441dc8442d80bda9aaaf9
Autor:
Shawn W. O'Driscoll, Gregory G. Reinholz, Q. Chen, T.J. Ruesink, A. Olivos-Meza, Michelle E. Casper, James S. Fitzsimmons, Kai Nan An
Publikováno v:
Osteoarthritis and Cartilage. 18:1183-1191
Summary Objective To compare the efficacy of in situ transforming growth factor-beta1 (TGF-β1)-pretreated periosteum to untreated periosteum for regeneration of osteochondral tissue in rabbits. Methods In the pretreatment group, 12 month-old New Zea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d9f1dbb74df43d6084d2077a582c98a
https://doi.org/10.1016/j.joca.2010.06.003
https://doi.org/10.1016/j.joca.2010.06.003
Autor:
James S. Fitzsimmons, Gregory G. Reinholz, Fong-Chin Su, Joris Bekkers, Michelle E. Casper, James J. Stone, Yih Wen Tarng, Shawn W. O'Driscoll, Kai Nan An
Publikováno v:
Journal of Biomedical Materials Research Part A. :156-163
The purpose of this study was to investigate the effect of directional fluid flow on periosteal chondrogenesis. Periosteal explants were harvested from 2-month-old rabbits and sutured onto poly-epsilon-caprolactone (PCL) scaffolds with the cambium la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b3dd5063e137818e57dc25c21dcade
https://doi.org/10.1002/jbm.a.32830
https://doi.org/10.1002/jbm.a.32830
Autor:
T.J. Ruesink, Shawn W. O'Driscoll, James S. Fitzsimmons, Michelle E. Casper, Jan C. Schagemann, H. W. Chung, Gregory G. Reinholz
Publikováno v:
Osteoarthritis and Cartilage. 17:723-734
SummaryObjectiveTo examine the potential for rejuvenation of aged periosteum by local injection of transforming growth factor-beta1 (TGF-β1) and insulin-like growth factor-1 (IGF-1) alone or in combination to induce cambium cell proliferation and en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5be32410afee1e5a9aa323b180ef587
https://doi.org/10.1016/j.joca.2008.10.011
https://doi.org/10.1016/j.joca.2008.10.011
Autor:
Jürgen Rohwedel, M. Fehr, Gregory G. Reinholz, Jan Kramer, Solomon F. D. Paul, C. Kaps, Michelle E. Casper, Jan C. Schagemann, H. Mittelstaedt
Publikováno v:
Journal of biomedical materials research. Part A. 101(6)
The objective of this study was to develop a scaffold for mesenchymal stromal cell (MSC) recruitment, proliferation, and chondrogenic differentiation. The concept behind the design is to mimic the cartilage matrix and contain stimulatory agents that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5334b26f58fd8d216303e0ec3fa5363
https://pubmed.ncbi.nlm.nih.gov/23184542
https://pubmed.ncbi.nlm.nih.gov/23184542
Autor:
Melissa Giuliani, Michelle E. Casper, Kristen L. Shogren, Mahrokh Dadsetan, Michael J. Yaszemski, Matthias Pumberger, Terry Ruesink, Theresa E. Hefferan, Bradford L. Currier
In this study we have compared the effects of negative and positive fixed charges on chondrocyte behavior in vitro. Electrical charges have been incorporated into oligo(poly(ethylene glycol) fumarate) (OPF) using small charged monomers such as sodium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e18c5a114b18f2024d11de9847d48b3c
https://europepmc.org/articles/PMC3103083/
https://europepmc.org/articles/PMC3103083/
Autor:
Scott W. Hiebert, Michelle E. Casper, Meghan E. McGee-Lawrence, Frank J. Secreto, Xiaodong Li, Bridget Stensgard, David F. Razidlo, Jennifer J. Westendorf, Tiffany J. Whitney, Sarah K. Knutson
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 7, p e11492 (2010)
PLoS ONE, Vol 5, Iss 7, p e11492 (2010)
Histone deacetylase (Hdac)3 is a nuclear enzyme that contributes to epigenetic programming and is required for embryonic development. To determine the role of Hdac3 in bone formation, we crossed mice harboring loxP sites around exon 7 of Hdac3 with m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47eece72005a9612a008ede0065badc4
https://pubmed.ncbi.nlm.nih.gov/20628553
https://pubmed.ncbi.nlm.nih.gov/20628553
Autor:
James S. Fitzsimmons, Mahrokh Dadsetan, Shawn W. O'Driscoll, Jan C. Schagemann, Gregory G. Reinholz, Michelle E. Casper, Eike Mrosek, Haymo Kurz, James S. Stone, Sun Yu-Long
Publikováno v:
Biomaterials. 31(10)
Previously we demonstrated that chondrocyte ECM synthesis and mitotic activity was dependent on scaffold composition when cultured on uncoated PCL scaffolds (pPCL) or PCL composites containing hyaluronan (PCL/HA), chitosan (PCL/CS), fibrin (PCL/F), o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f4be5e82259307dfa3e5d3a65696d3
https://pubmed.ncbi.nlm.nih.gov/20053441
https://pubmed.ncbi.nlm.nih.gov/20053441
Autor:
Gregory G. Reinholz, James J. Stone, Michelle E. Casper, T.J. Ruesink, Y. Huang, James S. Fitzsimmons, A.O. Meza, Shawn W. O'Driscoll
Publikováno v:
Osteoarthritis and Cartilage. (7):981-991
SummaryObjectiveTo determine the potential of periosteal cells to infiltrate poly-ɛ-caprolactone (PCL) nanofiber scaffolds in vivo and subsequently produce cartilage in vitro.DesignPCL nanofiber scaffolds, with or without chitosan-coating were impla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3112d41277d061064378c5dd936b9ab1