Výsledky vyhledávání - "Michelle E. Becker"

Supplementary Data, Figures and Table from HDAC1 Is a Required Cofactor of CBFβ-SMMHC and a Potential Therapeutic Target in Inversion 16 Acute Myeloid Leukemia

Autor: R. Katherine Hyde, Catalina Amador, Jacob T. Williams, Rachel A. Coburn, Michelle E. Becker, Yiqian Wang, Lisa E. Richter

Supplemental Figure 1. HDAC2 binding to CBFÎ²-SMMHC is not detected in transfected COS-7 cells. Supplemental Figure 2. CBFB-MYH11N63K, N104K, Î"179-221 mutant eliminates RUNX1 binding. Supplemental Figure 3. CBFB does not Co-IP with HDAC1. Supplem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206f62a25cdebde28a01e7d6ccda488e
https://doi.org/10.1158/1541-7786.22516240.v1

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Data from HDAC1 Is a Required Cofactor of CBFβ-SMMHC and a Potential Therapeutic Target in Inversion 16 Acute Myeloid Leukemia

Autor: R. Katherine Hyde, Catalina Amador, Jacob T. Williams, Rachel A. Coburn, Michelle E. Becker, Yiqian Wang, Lisa E. Richter

Acute myeloid leukemia (AML) is a neoplastic disease characterized by the uncontrolled proliferation and accumulation of immature myeloid cells. A common mutation in AML is the inversion of chromosome 16 [inv (16)], which generates a fusion between t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3aad4e1476dbc13e27bdf7f70c2068ec
https://doi.org/10.1158/1541-7786.c.6541321

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