Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Michelle Dubuc Mageau"'
Autor:
Michelle Dubuc-Mageau, Audrey Sanfacon, Andy Makin, Robert Tavcar, Christian Li, Luis Fernando Negro Silva, Roy Forster, Simon Authier, Paula Juliana Brizuela de Seadi Pereira, Wendy Tan
Publikováno v:
International Journal of Toxicology. 38:415-422
Minipigs are an emerging nonrodent alternative for ocular toxicology owing to anatomical similarities in the minipig eyes when compared to humans. Ocular structures and components from Göttingen minipigs were characterized and compared to species co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a0858396b33f2edb6685bf9ce62af18
https://doi.org/10.1177/1091581819867929
https://doi.org/10.1177/1091581819867929
Autor:
Audrey Sanfacon, Emmanuel Boulay, Ariane Menard, Eric Troncy, Hai Huang, Loïs S. Miraucourt, Michael K. Pugsley, Anne-Marie Downey, Mireille Guerrier, Michael V. Accardi, Wendy Tan, Simon Authier, Michelle Dubuc-Mageau
Publikováno v:
International journal of toxicology. 39(6)
Introduction: Corrected QT (QTc) interval is an essential proarrhythmic risk biomarker, but recent data have identified limitations to its use. The J to T-peak (JTp) interval is an alternative biomarker for evaluating drug-induced proarrhythmic risk.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3398e1cf1e8cfd89a6f00ce54b33011f
https://pubmed.ncbi.nlm.nih.gov/33063577
https://pubmed.ncbi.nlm.nih.gov/33063577
Autor:
Audrey Sanfacon, Emmanuel Boulay, Eric Troncy, Michael V. Accardi, Joseph C. Arezzo, Michelle Dubuc Mageau, Mylene Pouliot, Simon Authier, Stephanie Mignault Goulet, Wendy Tan, Dominique Paquette
Publikováno v:
Journal of pharmacological and toxicological methods. 97
Seizures are amongst the most frequent neurological issues encountered in pre-clinical safety testing. The objective was to characterize EEG morphologies and premonitory signs in drug-induced seizures in preclinical species. A comparative (inter-spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a93cecbcb5d89b8c58a9ea60b5c817f
https://pubmed.ncbi.nlm.nih.gov/30922951
https://pubmed.ncbi.nlm.nih.gov/30922951
Autor:
Emmanuel Boulay, Audrey Sanfacon, Dominique Paquette, Michelle Dubuc Mageau, Mylene Pouliot, Eric Troncy, Wendy Tan, Michael V. Accardi, Joseph C. Arezzo, Simon Authier, Stephanie Mignault Goulet
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 99:106611
Seizures are amongst the most frequent neurological issues encountered in pre-clinical safety testing. The objective was to characterize EEG morphologies and premonitory signs in drug-induced seizures in preclinical species. A comparative (inter-spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2608fa38775c377604a8c4f78cc1bac
https://doi.org/10.1016/j.vascn.2019.106611
https://doi.org/10.1016/j.vascn.2019.106611
Autor:
Michelle Dubuc-Mageau, Michael K. Pugsley, Emmanuel Boulay, Ariane Menard, Simon Authier, Wendy Tan, Audrey Sanfacon
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 99:106595
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::793b62e99a47a8ba22d5e1758fe6233f
https://doi.org/10.1016/j.vascn.2019.05.045
https://doi.org/10.1016/j.vascn.2019.05.045
Autor:
Wendy Tan, Dominique Paquette, Simon Authier, Audrey Sanfacon, Michael V. Accardi, Mylene Pouliot, Michelle Dubuc-Mageau
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 99:106595
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e78660f99e36356f0736f2e0eaa32b09
https://doi.org/10.1016/j.vascn.2019.05.001
https://doi.org/10.1016/j.vascn.2019.05.001