Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Michelle D. Combs"'
Autor:
Clarissa S. Craft, Terri A. Pietka, Samuel Klein, Trey Coleman, Timothy Schappe, Nada A. Abumrad, Robert P. Mecham, Michelle D. Combs
Publikováno v:
Diabetes. 63:1920-1932
Microfibril-associated glycoprotein 1 (MAGP1) is a component of extracellular matrix microfibrils. Here we show that MAGP1 expression is significantly altered in obese humans, and inactivation of the MAGP1 gene (Mfap2−/−) in mice results in adipo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b65eeb0a7e90692e7e82dbeb24e57246
https://doi.org/10.2337/db13-1604
https://doi.org/10.2337/db13-1604
Autor:
Michelle D. Combs, Chantel A. Miller, Jeffrey J. Atkinson, Holly M. Toennies, Barbara Crippes Trask, Clarissa S. Craft, Tom J. Brett, Robert P. Mecham, J. Michael Shipley, Russell H. Knutsen, Thomas J. Broekelmann, Daniel L. Kober
Publikováno v:
Journal of Biological Chemistry. 288:28869-28880
Background: The function of MAGP2 was studied by inactivating its gene (Mfap5−/−) in mice. Results: Mfap5−/− mice have a neutrophil deficiency and other phenotypes that are different from MAGP1- and fibrillin-deficient animals. Conclusion: MA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc3e2c58bd40d5510626d47ba34d9b8
https://doi.org/10.1074/jbc.m113.497727
https://doi.org/10.1074/jbc.m113.497727
Publikováno v:
Developmental Biology. 368(2):345-357
Epicardium-derived cells (EPDCs) invade the myocardium and differentiate into fibroblasts and vascular smooth muscle (SM) cells, which support the coronary vessels. The transcription factor Pod1 (Tcf21) is expressed in subpopulations of the epicardiu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c23406ab4f31a59324cdbc1e7b2e0c3
Publikováno v:
Pediatric Cardiology. 31:414-421
The development and normal function of the heart valves requires complex interactions among signaling molecules, transcription factors and structural proteins that are tightly regulated in time and space. Here we review the roles of critical transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f51824caa8e46051714fd42f6dd109b1
https://doi.org/10.1007/s00246-009-9616-x
https://doi.org/10.1007/s00246-009-9616-x
Autor:
Michelle D. Combs, Katherine E. Yutzey
Publikováno v:
Circulation Research. 105:565-574
Rationale: NFATc1 (nuclear factor of activated T-cells cytoplasmic 1) activity in endocardial cushion (ECC) endothelial cells is required for normal ECC growth and extracellular matrix (ECM) remodeling during heart valve development. Objective: The m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fcb7d5b00e9cfd8b865433980c1c9fc
https://doi.org/10.1161/circresaha.109.196469
https://doi.org/10.1161/circresaha.109.196469
Autor:
Katherine E. Yutzey, Michelle D. Combs
Publikováno v:
Circulation Research. 105:408-421
Abstract : In recent years, significant advances have been made in the definition of regulatory pathways that control normal and abnormal cardiac valve development. Here, we review the cellular and molecular mechanisms underlying the early developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7174833220fa49819a749efe4dba04c5
https://doi.org/10.1161/circresaha.109.201566
https://doi.org/10.1161/circresaha.109.201566
Autor:
John P. Perentesis, Michelle D. Combs, Beverly J. Lange, Julie A. Ross, Emily Stover, Todd A. Alonzo, Tiffany A. Zamzow, Stella M. Davies, James Elliott, Soheil Meschinchi, Robert B. Gerbing, Parinda A. Mehta
Publikováno v:
Clinical Cancer Research. 14:7896-7899
Purpose: FAS is a cell surface receptor involved in apoptotic signal transmission. Deregulation of this pathway results in down-regulation of apoptosis and subsequent persistence of a malignant clone. A single nucleotide polymorphism resulting in gua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f544919cb2e8db0476a50042d7ebeb8d
https://doi.org/10.1158/1078-0432.ccr-08-0418
https://doi.org/10.1158/1078-0432.ccr-08-0418
Autor:
Parinda A. Mehta, Margaret L. MacMillan, Stella M. Davies, Tiffany Zamzow, James Elliott, Mary Eapen, Michelle D. Combs, Effie W. Petersdorf, Richard Aplenc, Daniel J. Weisdorf, Sharavi Gandham, John P. Klein
Publikováno v:
British Journal of Haematology. 137:152-157
Allogeneic haematopoietic stem cell transplantation (HSCT) offers a potential cure for a variety of malignant and non-malignant conditions. However, regimen-related toxicity, graft-versus-host disease (GVHD), and opportunistic infections (Kernan et a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c62dc2d3b9cef8b70b5f169d52d9266a
https://doi.org/10.1111/j.1365-2141.2007.06552.x
https://doi.org/10.1111/j.1365-2141.2007.06552.x
Publikováno v:
Developmental Biology. 356(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::707969ab1689c153ee0fd1b8fb6ab90c
Autor:
Caitlin M. Braitsch, Katherine E. Yutzey, Jeanne James, Michelle D. Combs, Alexander W. Lange
Epicardium-derived cells (EPDCs) contribute to formation of coronary vessels and fibrous matrix of the mature heart. Nuclear factor of activated T-cells cytoplasmic 1 (NFATC1) is expressed in cells of the proepicardium (PE), epicardium and EPDCs in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a64cf7386481429825eade509328ee84
https://europepmc.org/articles/PMC3074451/
https://europepmc.org/articles/PMC3074451/
