Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Michelle D Rojo"'
Autor:
Kylie L Mills, Angelica M Gomes, Courtney R Standlee, Michelle D Rojo, Peter Carmeliet, Zhen Lin, Heather L Machado
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208550 (2018)
Mammary gland development is a complex and dynamic process that occurs mainly postnatally. Ductal elongation and branching morphogenesis are regulated by a plethora of factors, including cytokines, hormones, growth factors and the extracellular matri
Externí odkaz:
https://doaj.org/article/8e94b03588c14fdf8e336603a4a60e3a
Autor:
Ayman M. Ibrahim, Matthew A. Moss, Zane Gray, Michelle D. Rojo, Caitlin M. Burke, Kathryn L. Schwertfeger, Camila O. dos Santos, Heather L. Machado
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Myeloid cell heterogeneity remains poorly studied in breast cancer, and particularly in premalignancy. Here, we used single cell RNA sequencing to characterize macrophage diversity in mouse pre-invasive lesions as compared to lesions undergoing local
Externí odkaz:
https://doaj.org/article/b4a1669710614bc09b7acf844aab3c82
Autor:
Michelle D. Rojo, Caitlin M. Burke, Alexa M. Dow, Kathryn L. Schwertfeger, Heather L. Machado
Publikováno v:
Cancer Research. 82:3162-3162
Throughout mammary gland development, there are distinct stages that are “hot spots” of breast cancer risk. During these critical windows, tissue resident macrophages function to maintain the homeostatic balance within the stromal microenvironmen
Publikováno v:
Cancer Research. 82:933-933
Breast cancer growth and progression relies on complex interactions between tumor cells and surrounding stromal cells, including immune cells. Infiltrating immune cells, including macrophages, have been shown to promote tumor progression and metastas
Autor:
Caitlin M. Burke, Michelle D. Rojo, Jeffery M. Rosen, Tobias Ackermann, Christine Muller, Cornelis F. Calkhoven, Heather L. Machado
Publikováno v:
Cancer Research. 82:915-915
Breast tumorigenesis relies on complex interactions between tumor cells and their surrounding environment, orchestrated by tightly regulated transcriptional networks. While much is known about the signaling pathways affecting breast cancer cell growt
Publikováno v:
Journal of the Endocrine Society
Macrophages are necessary in mammary gland development to drive ductal elongation and have been shown to promote cancer metastasis. Our laboratory has previously shown that macrophages are recruited to pre-invasive lesions to induce localized invasio
Autor:
Zhen Lin, Peter Carmeliet, Heather L. Machado, Michelle D. Rojo, Angelica M. Gomes, Courtney R. Standlee, Kylie L. Mills
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208550 (2018)
PLoS ONE
PLoS ONE
Mammary gland development is a complex and dynamic process that occurs mainly postnatally. Ductal elongation and branching morphogenesis are regulated by a plethora of factors, including cytokines, hormones, growth factors and the extracellular matri