Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Michelle D Audsley"'
Autor:
Gayathri Manokaran, Michelle D Audsley, Haruka Funakoda, Cassandra T David, Katherine A Garnham, Stephen M Rawlinson, Celine Deffrasnes, Naoto Ito, Gregory W Moseley
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010533 (2022)
Antagonism of the interferon (IFN)-mediated antiviral state is critical to infection by rabies virus (RABV) and other viruses, and involves interference in the IFN induction and signaling pathways in infected cells, as well as deactivation of the ant
Externí odkaz:
https://doaj.org/article/38bb142f9a684fadbe3d07c7a9074010
Autor:
Maya Shemesh, Turgut E Aktepe, Joshua M Deerain, Julie L McAuley, Michelle D Audsley, Cassandra T David, Damian F J Purcell, Victoria Urin, Rune Hartmann, Gregory W Moseley, Jason M Mackenzie, Gideon Schreiber, Daniel Harari
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009800 (2021)
Type I Interferons (IFN-Is) are a family of cytokines which play a major role in inhibiting viral infection. Resultantly, many viruses have evolved mechanisms in which to evade the IFN-I response. Here we tested the impact of expression of 27 differe
Externí odkaz:
https://doaj.org/article/a1d78fad6c5f4fa381f8684888d7c0c1
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 3, p e0005426 (2017)
BACKGROUND:Dengue virus (DENV) is primarily vectored by the mosquito Aedes aegypti, and is estimated to cause 390 million human infections annually. A novel method for DENV control involves stable transinfection of Ae. aegypti with the common insect
Externí odkaz:
https://doaj.org/article/d26889946eff4cdf81715e9b48426a49
Autor:
Sundy N. Y. Yang, Sarah C. Atkinson, Michelle D. Audsley, Steven M. Heaton, David A. Jans, Natalie A. Borg
Publikováno v:
Cells, Vol 9, Iss 1, p 170 (2020)
Viral disease is one of the greatest burdens for human health worldwide, with an urgent need for efficacious antiviral strategies. While antiviral drugs are available, in many cases, they are prone to the development of drug resistance. A way to over
Externí odkaz:
https://doaj.org/article/4f0b210aaf3d40578aff1ed5a75063b4
Autor:
Maya Shemesh, Turgut E. Aktepe, Joshua M. Deerain, Julie L. McAuley, Michelle D. Audsley, Cassandra T. David, Damian F. J. Purcell, Victoria Urin, Rune Hartmann, Gregory W. Moseley, Jason M. Mackenzie, Gideon Schreiber, Daniel Harari
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12 (2021)
Autor:
Gayathri Manokaran, Michelle D. Audsley, Haruka Funakoda, Cassandra T. David, Katherine A. Garnham, Stephen M. Rawlinson, Celine Deffrasnes, Naoto Ito, Gregory W. Moseley
Publikováno v:
PLoS pathogens. 18(5)
Antagonism of the interferon (IFN)-mediated antiviral state is critical to infection by rabies virus (RABV) and other viruses, and involves interference in the IFN induction and signaling pathways in infected cells, as well as deactivation of the ant
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 9094, p 9094 (2021)
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 9094, p 9094 (2021)
The cytoplasmic retinoic acid-inducible gene-I (RIG-I)-like receptors (RLRs) initiate interferon (IFN) production and antiviral gene expression in response to RNA virus infection. Consequently, RLR signalling is tightly regulated by both host and vir
Autor:
Paul R. Young, Michelle D. Audsley, Cassandra Koh, Emily J Kerton, Edward C. Holmes, Elizabeth A. McGraw, Francesca Di Giallonardo
Publikováno v:
Virus Evolution
Wolbachia is an intracellular endosymbiont of insects that inhibits the replication of a range of pathogens in its arthropod hosts. The release of Wolbachia into wild populations of mosquitoes is an innovative biocontrol effort to suppress the transm
Autor:
Steven M. Heaton, David A. Jans, Sundy N.Y. Yang, Michelle D. Audsley, Natalie A. Borg, Sarah C. Atkinson
Publikováno v:
Cells
Cells, Vol 9, Iss 1, p 170 (2020)
Volume 9
Issue 1
Cells, Vol 9, Iss 1, p 170 (2020)
Volume 9
Issue 1
Viral disease is one of the greatest burdens for human health worldwide, with an urgent need for efficacious antiviral strategies. While antiviral drugs are available, in many cases, they are prone to the development of drug resistance. A way to over
Autor:
Mang Shi, Francesca Di Giallonardo, Edward C. Holmes, Michelle D. Audsley, Paul R. Young, Elizabeth A. McGraw
Publikováno v:
The Journal of general virology. 99(6)
A novel negative-sense RNA virus, Aedes aegypti anphevirus, was recently identified in wild Aedes aegypti mosquitoes. We show that this virus is also present in the Aag2 Aedes aegypti cell line and characterize its complete genome and evolutionary hi