Zobrazeno 1 - 10
of 190
pro vyhledávání: '"Michelle D, Garrett"'
Autor:
Steven R. Whittaker, Clare Barlow, Mathew P. Martin, Caterina Mancusi, Steve Wagner, Annette Self, Elaine Barrie, Robert Te Poele, Swee Sharp, Nathan Brown, Stuart Wilson, Wayne Jackson, Peter M. Fischer, Paul A. Clarke, Michael I. Walton, Edward McDonald, Julian Blagg, Martin Noble, Michelle D. Garrett, Paul Workman
Publikováno v:
Molecular Oncology, Vol 12, Iss 3, Pp 287-304 (2018)
Deregulation of the cyclin‐dependent kinases (CDKs) has been implicated in the pathogenesis of multiple cancer types. Consequently, CDKs have garnered intense interest as therapeutic targets for the treatment of cancer. We describe herein the molec
Externí odkaz:
https://doaj.org/article/fe1e3db27bb44f2e82c1a7b2ffc32006
Autor:
Bini Claringbold, Alex H. de Vries, Christopher J. Serpell, Nadeema Appukutti, Michael R. Reithofer, Michelle D. Garrett, Prashant G. Gudeangadi
Publikováno v:
Chemical communications (Cambridge, England), 58(87), 12200-12203. ROYAL SOC CHEMISTRY
Development of the interplay between monomer sequence and supramolecular chemistry is critical if chemistry is to recapitulate the properties of proteins and nucleic acids in the synthetic world. We have created sequenced trimers of aromatic donor/ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2460b73bfaccc49acdba006c52cff8b
https://doi.org/10.1039/d2cc00239f
https://doi.org/10.1039/d2cc00239f
Autor:
Jill E. Hunter, Amy E. Campbell, Nicola L. Hannaway, Scott Kerridge, Saimir Luli, Jacqueline A. Butterworth, Helene Sellier, Reshmi Mukherjee, Nikita Dhillon, Praveen D. Sudhindar, Ruchi Shukla, Philip J. Brownridge, Hayden L. Bell, Jonathan Coxhead, Leigh Taylor, Peter Leary, Megan S.R. Hasoon, Ian Collins, Michelle D. Garrett, Claire E. Eyers, Neil D. Perkins
Publikováno v:
Biochemical Journal. 479:2063-2086
Previously, we discovered that deletion of c-Rel in the Eµ-Myc mouse model of lymphoma results in earlier onset of disease, a finding that contrasted with the expected function of this NF-κB subunit in B-cell malignancies. Here we report that Eµ-M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df12386d5171f9c615727f2b67ddab70
https://doi.org/10.1042/bcj20220102
https://doi.org/10.1042/bcj20220102
Autor:
Jill E. Hunter, Amy E. Campbell, Jacqueline A. Butterworth, Helene Sellier, Nicola L. Hannaway, Saimir Luli, Achilleas Floudas, Niall S. Kenneth, Adam J. Moore, Philip J. Brownridge, Huw D. Thomas, Jonathan Coxhead, Leigh Taylor, Peter Leary, Megan S.R. Hasoon, Andrew M. Knight, Michelle D. Garrett, Ian Collins, Claire E. Eyers, Neil D. Perkins
Publikováno v:
Biochemical Journal. 479:2087-2113
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::420474f3df9a1bc6e42295d95643c992
https://doi.org/10.1042/bcj20220089
https://doi.org/10.1042/bcj20220089
Autor:
Udai Banerji, Stan B Kaye, Martin Gore, Johann S. de Bono, Paul Workman, Paul A. Clarke, Michelle D. Garrett, Gerhardt Attard, Susana Miranda, Mateus Crespo, Lorna Pope, Emma Kipps, Parames Thavasu, Adam Stewart, Craig P. Carden
PDF file, 47KB, Reproducibility of immunomagnetic separation and ELISA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c04e3d9be821c1e363e85ad784184e1
https://doi.org/10.1158/1535-7163.22498921.v1
https://doi.org/10.1158/1535-7163.22498921.v1
Autor:
Udai Banerji, Stan B Kaye, Martin Gore, Johann S. de Bono, Paul Workman, Paul A. Clarke, Michelle D. Garrett, Gerhardt Attard, Susana Miranda, Mateus Crespo, Lorna Pope, Emma Kipps, Parames Thavasu, Adam Stewart, Craig P. Carden
PDF file, 80KB, Experiments detailing the validation of immunomagnetic separation and ELISA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac9a371d153bff7ac063b7a52a81919b
https://doi.org/10.1158/1535-7163.22498927
https://doi.org/10.1158/1535-7163.22498927
Autor:
Michelle D. Garrett, Ian Collins, Paul Workman, Suzanne A. Eccles, Florence I. Raynaud, Wynne Aherne, Neil T. Thompson, John J. Caldwell, Gowri Vijayaraghavan, Lisa Pickard, Alan Henley, Simon P. Heaton, Ruth Ruddle, Paul D. Eve, Alexis de Haven Brandon, Melanie Valenti, Lisa-Jane K. Hunter, Mike I. Walton, Timothy A. Yap
Supplementary Figures 1-4 from Preclinical Pharmacology, Antitumor Activity, and Development of Pharmacodynamic Markers for the Novel, Potent AKT Inhibitor CCT128930
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152e6b9e2a7c0fc3cf17558fd7b2c7b2
https://doi.org/10.1158/1535-7163.22496215.v1
https://doi.org/10.1158/1535-7163.22496215.v1
Autor:
Michelle D. Garrett, Ian Collins, Paul Workman, Suzanne A. Eccles, Florence I. Raynaud, Wynne Aherne, Neil T. Thompson, John J. Caldwell, Gowri Vijayaraghavan, Lisa Pickard, Alan Henley, Simon P. Heaton, Ruth Ruddle, Paul D. Eve, Alexis de Haven Brandon, Melanie Valenti, Lisa-Jane K. Hunter, Mike I. Walton, Timothy A. Yap
Supplementary Figure Legends and Supplementary Table 1 from Preclinical Pharmacology, Antitumor Activity, and Development of Pharmacodynamic Markers for the Novel, Potent AKT Inhibitor CCT128930
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67936b34bb07aa265992163ae6426afc
https://doi.org/10.1158/1535-7163.22496218.v1
https://doi.org/10.1158/1535-7163.22496218.v1
Autor:
Udai Banerji, Stan B Kaye, Martin Gore, Johann S. de Bono, Paul Workman, Paul A. Clarke, Michelle D. Garrett, Gerhardt Attard, Susana Miranda, Mateus Crespo, Lorna Pope, Emma Kipps, Parames Thavasu, Adam Stewart, Craig P. Carden
PDF file, 63KB.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0931bff00a6062d2f8354fbf202e2a41
https://doi.org/10.1158/1535-7163.22498915
https://doi.org/10.1158/1535-7163.22498915
Autor:
Udai Banerji, Stan B Kaye, Martin Gore, Johann S. de Bono, Paul Workman, Paul A. Clarke, Michelle D. Garrett, Gerhardt Attard, Susana Miranda, Mateus Crespo, Lorna Pope, Emma Kipps, Parames Thavasu, Adam Stewart, Craig P. Carden
PDF file, 66KB, Oncogenes and mutations detected using the OncoCarta Panel v1.0.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a1ca090a81273845ea10a1d5086822
https://doi.org/10.1158/1535-7163.22498912.v1
https://doi.org/10.1158/1535-7163.22498912.v1