Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Michelle Chamblee"'
Autor:
Yuexiu Zhang, Michelle Chamblee, Jiayu Xu, Panke Qu, Mohamed M. Shamseldin, Sung J. Yoo, Jack Misny, Ilada Thongpan, Mahesh KC, Jesse M. Hall, Yash A. Gupta, John P. Evans, Mijia Lu, Chengjin Ye, Cheng Chih Hsu, Xueya Liang, Luis Martinez-Sobrido, Jacob S. Yount, Prosper N. Boyaka, Shan-Lu Liu, Purnima Dubey, Mark E. Peeples, Jianrong Li
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract As the new SARS-CoV-2 Omicron variants and subvariants emerge, there is an urgency to develop intranasal, broadly protective vaccines. Here, we developed highly efficacious, intranasal trivalent SARS-CoV-2 vaccine candidates (TVC) based on t
Externí odkaz:
https://doaj.org/article/8d4eee26f0fd4441806ce1eeeb848da8
Autor:
Pei Li, Yajie Liu, Julia N. Faraone, Cheng Chih Hsu, Michelle Chamblee, Yi-Min Zheng, Claire Carlin, Joseph S. Bednash, Jeffrey C. Horowitz, Rama K. Mallampalli, Linda J. Saif, Eugene M. Oltz, Daniel Jones, Jianrong Li, Richard J. Gumina, Shan-Lu Liu
Publikováno v:
mBio, Vol 15, Iss 5 (2024)
ABSTRACTThe rapid evolution of SARS-CoV-2 variants presents a constant challenge to the global vaccination effort. In this study, we conducted a comprehensive investigation into two newly emerged variants, BA.2.87.1 and JN.1, focusing on their neutra
Externí odkaz:
https://doaj.org/article/95cbede0c59042fca721a9fccb79db49
Autor:
Mijia Lu, Michelle Chamblee, Yuexiu Zhang, Chengjin Ye, Piyush Dravid, Jun-Gyu Park, KC Mahesh, Sheetal Trivedi, Satyapramod Murthy, Himanshu Sharma, Cole Cassady, Supranee Chaiwatpongsakorn, Xueya Liang, Jacob S. Yount, Prosper N. Boyaka, Mark E. Peeples, Luis Martinez-Sobrido, Amit Kapoor, Jianrong Li
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(35)
The spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the main target for neutralizing antibodies (NAbs). The S protein trimer is anchored in the virion membrane in its prefusion (preS) but metastable form. The preS
Autor:
Yuexiu Zhang, Mijia Lu, K C Mahesh, Eunsoo Kim, Mohamed M. Shamseldin, Chengjin Ye, Piyush Dravid, Michelle Chamblee, Jun-Gyu Park, Jesse M. Hall, Sheetal Trivedi, Supranee Chaiwatpongsakorn, Adam D. Kenny, Satyapramod Srinivasa Murthy, Himanshu Sharma, Xueya Liang, Jacob S. Yount, Amit Kapoor, Luis Martinez-Sobrido, Purnima Dubey, Prosper N. Boyaka, Mark E. Peeples, Jianrong Li
Publikováno v:
Proceedings of the National Academy of Sciences. 119
With the rapid increase in SARS-CoV-2 cases in children, a safe and effective vaccine for this population is urgently needed. The MMR (measles/mumps/rubella) vaccine has been one of the safest and most effective human vaccines used in infants and chi