Výsledky vyhledávání - "Michelle Chain"

Annotation of the non-canonical translatome reveals that CHO cell microproteins are a new class of mAb drug product impurity

Autor: Marina Castro-Rivadeneyra, Ioanna Tzani, Paul Kelly, Lisa Strasser, Felipe Guapo, Ciara Tierney, Michelle Chain, Lin Zhang, Martin Clynes, Barry L. Karger, Niall Barron, Jonathan Bones, Colin Clarke

Chinese hamster ovary (CHO) cells are used to produce almost 90% of therapeutic monoclonal antibodies (mAbs). The annotation of non-canonical translation events in these cellular factories remains incomplete, limiting not only our ability to study CH

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4e542ec0a048420331458321dd0f2797
https://doi.org/10.1101/2022.01.20.475618

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