Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Michelle Carbuto"'
Autor:
Deepak Cyril D’Souza, Richard E. Carson, Naomi Driesen, Jason Johannesen, Mohini Ranganathan, John H. Krystal, Kyung-Heup Ahn, Kimberlee Bielen, Michelle Carbuto, Emma Deaso, Mika Naganawa, Nabeel Nabulsi, Ming-Qiang Zheng, Shu-fei Lin, Yiyun Huang, Peter T. Morgan, Raymond Suckow, George He, Gregory McCarthy, Joshua Kenney, Joel Gelernter, Ralitza Gueorguieva, Brian Pittman
Publikováno v:
Biological psychiatry. 84(6)
Background Glycine transporter-1 (GlyT1) inhibitors may ameliorate cognitive impairments associated with schizophrenia. The dose-related occupancy and target engagement of the GlyT1 inhibitor PF-03463275 were studied to inform optimal dose selection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::341324dc16b45ea6978d93b0af390f07
https://pubmed.ncbi.nlm.nih.gov/30165949
https://pubmed.ncbi.nlm.nih.gov/30165949
Autor:
Mohini Ranganathan, Ashley M. Schnakenberg-Martin, Deepak Cyril D'Souza, Peter H. Addy, Jacqueline Elander, Michelle Carbuto, Patrick D. Skosnik, Rajiv Radhakrishnan, Ashley Williams, R. Andrew Sewell, Brian Pittman
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 79
Introduction Cannabis and agonists of the brain cannabinoid receptor (CB1R) produce acute memory impairments in humans. However, the extent to which cannabinoids impair the component processes of encoding and retrieval has not been established in hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27665b1b708f0e2015dadfbe01da9168
https://pubmed.ncbi.nlm.nih.gov/28642081
https://pubmed.ncbi.nlm.nih.gov/28642081
Autor:
Deepak Cyril D'Souza, Mohini Ranganathan, Jacqueline Elander, Michelle Carbuto, Brian Pittman, Ashley Schnakenberg, Rajiv Radhakrishnan, R. Andrew Sewell
Publikováno v:
Psychopharmacology. 231:2385-2393
A family history (FH) of alcoholism accounts for approximately 50% of the risk of developing alcohol problems. Several lines of preclinical evidence suggest that brain cannabinoid receptor (CB1R) function may mediate the effects of alcohol and risk f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f8f4439c6e13c9e7313f2758970b89
https://doi.org/10.1007/s00213-013-3402-4
https://doi.org/10.1007/s00213-013-3402-4
Autor:
Mohini Ranganathan, Deepak Cyril D'Souza, Brian J. Roach, Ashley Schnakenberg, Nagendra M. Singh, Jacqueline Elander, Michelle Carbuto, Patrick D. Skosnik, Daniel J. Fridberg, R. Andrew Sewell, Ashley Williams, Brian Pittman, Daniel H. Mathalon
Publikováno v:
Neuropsychopharmacology. 37:1632-1646
Cannabinoids induce a host of perceptual alterations and cognitive deficits in humans. However, the neural correlates of these deficits have remained elusive. The current study examined the acute, dose-related effects of delta-9-tetrahydrocannabinol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::670af20bc5e99009c66bf2994056c7b4
https://doi.org/10.1038/npp.2012.8
https://doi.org/10.1038/npp.2012.8
Autor:
Mohini Ranganathan, Joanna Udo de Haes, Pierre Peeters, Nagendra M. Singh, Deepak Cyril D'Souza, Jacques Schipper, Brian Pittman, Jacqueline Elander, Michelle Carbuto, Magnus Sjögren
Publikováno v:
Neuropsychopharmacology. 37:1036-1046
Enhancing glutamate function by stimulating the glycine site of the NMDA receptor with glycine, D-serine, or with drugs that inhibit glycine reuptake may have therapeutic potential in schizophrenia. The effects of a single oral dose of cis-N-methyl-N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2804639811abd8a6c8ec287ead1e2d0
https://doi.org/10.1038/npp.2011.295
https://doi.org/10.1038/npp.2011.295
Autor:
Deepak Cyril D'Souza, R. Andrew Sewell, Edward Perry, Jacqueline Elander, Michelle Carbuto, Gabriel Braley, Savita G. Bhakta, Mohini Ranganathan, Kim Forselius-Bielen, Brian Pittman, Ashley Williams, Ashley Schnakenberg
Publikováno v:
Psychopharmacology. 219:885-896
Delta-9-tetrahydrocannabinol (THC) is one of the few cannabinoid receptor ligands that can be used to probe the cannabinoid system in humans. Despite increasing interest in the cannabinoid receptor system, use of intravenous THC as a research tool ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67756f04df316c64b13870fc28aa3a8b
https://doi.org/10.1007/s00213-011-2417-y
https://doi.org/10.1007/s00213-011-2417-y
Autor:
John D. Cahill, Deepak Cyril D'Souza, Fred Bois, Jose Cortes-Briones, Ashley Schnakenberg, Mohini Ranganathan, Patrick D. Skosnik, Handan Gunduz-Bruce, Michelle Carbuto, Rajiv Radhakrishnan, R. Andrew Sewell, Brian Pittman
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 40(8)
Emerging evidence supports a number of associations between cannabis and psychosis/psychotic disorders, including schizophrenia. Acute exposure to both cannabis and synthetic cannabinoids (CBs) (including Spice and K2) can produce a range of transien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c784d43424b3919b8da5d662eeaeeb
https://pubmed.ncbi.nlm.nih.gov/25728472
https://pubmed.ncbi.nlm.nih.gov/25728472
Autor:
Mohini Ranganathan, Irina Esterlis, Deepak Cyril D'Souza, John Seibyl, Julie K. Staley, Maegan Krasenics, Michelle Carbuto, Frederic Bois, Brian Pittman, Kelly P. Cosgrove
There is a strong association between cigarette smoking and schizophrenia. Nicotine's actions in the brain are mediated through nicotinic acetylcholine receptors. Those containing α(4) and β(2) subunits are the most abundant ones in the brain, have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cee9b0ccadf662b3979beef27d7a55a5
https://europepmc.org/articles/PMC3881431/
https://europepmc.org/articles/PMC3881431/
Autor:
Deepak Cyril, D'Souza, Daniel J, Fridberg, Patrick D, Skosnik, Ashley, Williams, Brian, Roach, Nagendra, Singh, Michelle, Carbuto, Jacqueline, Elander, Ashley, Schnakenberg, Brian, Pittman, R Andrew, Sewell, Mohini, Ranganathan, Daniel, Mathalon
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 37(7)
Cannabinoids induce a host of perceptual alterations and cognitive deficits in humans. However, the neural correlates of these deficits have remained elusive. The current study examined the acute, dose-related effects of delta-9-tetrahydrocannabinol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c36d9f577b179ace038534b54457f477
https://pubmed.ncbi.nlm.nih.gov/22334121
https://pubmed.ncbi.nlm.nih.gov/22334121
Autor:
Michelle, Carbuto, R Andrew, Sewell, Ashley, Williams, Kim, Forselius-Bielen, Gabriel, Braley, Jacqueline, Elander, Brian, Pittman, Ashley, Schnakenberg, Savita, Bhakta, Edward, Perry, Mohini, Ranganathan, Deepak Cyril, D'Souza, Yu-te, Wu
Publikováno v:
Psychopharmacology. 219(3)
Delta-9-tetrahydrocannabinol (THC) is one of the few cannabinoid receptor ligands that can be used to probe the cannabinoid system in humans. Despite increasing interest in the cannabinoid receptor system, use of intravenous THC as a research tool ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a5e5e2b7efcac75b137792b3d00a6f5b
https://pubmed.ncbi.nlm.nih.gov/21845389
https://pubmed.ncbi.nlm.nih.gov/21845389