Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Michelle C. Stone"'
Publikováno v:
Cell Reports, Vol 6, Iss 2, Pp 247-253 (2014)
Axon injury triggers regeneration through activation of a conserved kinase cascade, which includes the dual leucine zipper kinase (DLK). Although dendrites are damaged during stroke, traumatic brain injury, and seizure, it is not known whether mature
Externí odkaz:
https://doaj.org/article/06c69535ca0248569f4936d52cdd6fdd
Autor:
Michelle C. Stone, Kavitha Rao, Kyle W. Gheres, Seahee Kim, Juan Tao, Caroline La Rochelle, Christin T. Folker, Nina T. Sherwood, Melissa M. Rolls
Publikováno v:
Cell Reports, Vol 2, Iss 5, Pp 1340-1350 (2012)
Axon regeneration allows neurons to repair circuits after trauma; however, most of the molecular players in this process remain to be identified. Given that microtubule rearrangements have been observed in injured neurons, we tested whether microtubu
Externí odkaz:
https://doaj.org/article/bd59bc15c0f749f1a5255fbb5f23ec60
Autor:
J Ian Hertzler, Jiajing Teng, Annabelle R Bernard, Michelle C Stone, Hannah L Kline, Gibarni Mahata, Nitish Kumar, Melissa M Rolls
Publikováno v:
PLoS Genetics, Vol 20, Iss 8, p e1011388 (2024)
Most neurons are not replaced after injury and thus possess robust intrinsic mechanisms for repair after damage. Axon injury triggers a calcium wave, and calcium and cAMP can augment axon regeneration. In comparison to axon regeneration, dendrite reg
Externí odkaz:
https://doaj.org/article/483122d715f74004b997f5e787ff4802
Publikováno v:
Developmental Biology. 488:114-119
Axon regeneration in response to injury has been documented in many animals over several hundred years. In contrast, how neurons respond to dendrite injury has been examined only in the last decade. So far, dendrite regeneration after injury has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e3279a08e1c607d32d051c9836011de
https://doi.org/10.1016/j.ydbio.2022.05.014
https://doi.org/10.1016/j.ydbio.2022.05.014
Publikováno v:
Journal of Experimental Biology.
Axon regeneration helps maintain lifelong function of neurons in many animals. Depending on the site of injury, new axons can grow either from the axon stump (after distal injury) or from the tip of a dendrite (after proximal injury). However, some n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23e815b0789cfcdb5f3ce78319afcc8e
https://doi.org/10.1242/jeb.245717
https://doi.org/10.1242/jeb.245717
Autor:
Kavitha Rao, Alvaro Sagasti, Matthew Shorey, Floyd J. Mattie, Melissa M. Rolls, Michelle C. Stone
Publikováno v:
Dev Biol
Dorsal root ganglion (DRG) neurons are the predominant cell type that innervates the vertebrate skin. They are typically described as pseudounipolar cells that have central and peripheral axons branching from a single root exiting the cell body. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7fa0438a745ae129b1b552e861db9f9
https://doi.org/10.1016/j.ydbio.2021.06.007
https://doi.org/10.1016/j.ydbio.2021.06.007
Autor:
Joseph M. Cleary, Chengye Feng, James I. Hertzler, William O. Hancock, Alexis T. Weiner, Melissa M. Rolls, Gregory O. Kothe, Michelle C. Stone
Publikováno v:
J Cell Sci
Axons and dendrites are distinguished by microtubule polarity. In Drosophila, dendrites are dominated by minus-end-out microtubules, whereas axons contain plus-end-out microtubules. Local nucleation in dendrites generates microtubules in both orienta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691add0bf2b4094ed13717d92c0d053d
https://europepmc.org/articles/PMC8214762/
https://europepmc.org/articles/PMC8214762/
Publikováno v:
Dev Biol
Neurons extend dendrites and axons to receive and send signals. If either type of process is removed, the cell cannot function. Rather than undergoing cell death, some neurons can regrow axons and dendrites. Axon and dendrite regeneration have been e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e2f7f9807f669832a5bb672cf44483
https://pubmed.ncbi.nlm.nih.gov/32687893
https://pubmed.ncbi.nlm.nih.gov/32687893
Publikováno v:
Journal of Experimental Biology.
The centralized nervous systems of bilaterian animals rely on directional signaling facilitated by polarized neurons with specialized axons and dendrites. It is not known whether axo-dendritic polarity is exclusive to bilaterians or was already prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efa7e797e0a3a93f4f15e7473d18bd43
https://doi.org/10.1242/jeb.233197
https://doi.org/10.1242/jeb.233197
Autor:
Alexis T. Weiner, Michelle C. Stone, Chaoming Zhou, Edwin S. Levitan, Melissa M. Rolls, Kyle W. Gheres, Kavitha Rao, David L. Deitcher
Publikováno v:
Molecular Biology of the Cell
A Drosophila model system is used to show that the hereditary spastic paraplegia proteins spastin and atlastin help axons but not dendrites regenerate. The endoplasmic reticulum concentrates at tips of regenerating axons but not dendrites, and this d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ffcf026b9b263d99e6e4f84f34dbd7
http://europepmc.org/articles/PMC5170858
http://europepmc.org/articles/PMC5170858